With AI, we help every scientist reshape biology.

Joined November 2024
Hello World 👋 Today we are unveiling Boltz PBC, a Public Benefit Corporation to advance AI for biology through open science, and make it accessible to every scientist building a healthier future. Follow to stay up to date, and read more on our manifesto: boltz.bio/manifesto
Big news from Boltz today: we’re launching Boltz Lab, a new platform with new small-molecule + protein design agents, announcing Boltz PBC and a $28M seed round, and sharing a multi-year partnership with Pfizer. More below! 🚀
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BMS scientists have long been part of our open-source community. Now we're building together! We're excited to bring our latest models together with decades of BMS science, and put better molecular design tools in the hands of the scientists using them.
Today at GTC, we’re excited to announce our collaboration with Bristol Myers Squibb to bring the latest Boltz models into BMS’s drug discovery workflows. @bmsnews @boltz_bio 🚀🧵
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Well that was something. Means a lot to have the backing of @JensenHuang and the @nvidia team.
Cheers to the UK’s AI builders. 🇬🇧 Tonight in London, @JensenHuang announced new investments in @boltz_bio, @ForesightWorks, @hivergeai, @PrimaMente, and Riverlane. From new medicines to quantum computing, there’s plenty to build.
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Boltz retweeted
Cheers to the UK’s AI builders. 🇬🇧 Tonight in London, @JensenHuang announced new investments in @boltz_bio, @ForesightWorks, @hivergeai, @PrimaMente, and Riverlane. From new medicines to quantum computing, there’s plenty to build.
🤖 Made with AI
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🚀🚀🚀🚀🚀🚀🚀🚀🚀
Boltz on Times Square! Proud to see our team be part of the Disruptors 60 Class of 2026 and to see our work bringing AI-based biomolecular design to every scientist recognized. Thank you to our team, our partners and the scientists building with Boltz!
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Boltz on Times Square! Proud to see our team be part of the Disruptors 60 Class of 2026 and to see our work bringing AI-based biomolecular design to every scientist recognized. Thank you to our team, our partners and the scientists building with Boltz!
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👀 Next up: @pas_saro and @NoahBGetz from @boltz_bio present on their approaches to maximizing performance on structure and affinity prediction in the Boltz model series, and their work on using BoltzMol-1 to identify a target inhibiting DNA damage repair. #MoML2026
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BoltzMol-1 can now design within WuXi GalaXi! Adding new diversity to the virtual space searchable by BoltzMol-1, this 25B sized synthesis-ready compound library is now available in Boltz Lab and using our Boltz API.
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Read our BoltzMol-1 technical report to learn more about how BoltzMol-1 can rapidly and efficiently be deployed for hit-finding through ultra-large virtual libraries. Design new small-molecules today at lab[.]boltz[.]com!
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We’re thrilled to launch the Alzheimer’s Translation Challenge, a global AI competition to discover new therapeutic targets for Alzheimer’s disease and translate them into novel molecules!
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The competition will unfold in two stages: first, participants will use large-scale cell data to build AI models and identify promising therapeutic targets. Then, shortlisted teams will work with Boltz to design and develop novel molecules against those targets, testing them in Prima Mente’s wet lab to validate their therapeutic potential.
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At Boltz we are excited to support this challenge led by @PrimaMente in partnership with the @AlzData, with @nvidia, @huggingface, @nebiusai, Talisman Therapeutics, @ultimagenomics, @Cellanome, @PrimeIntellect, and @GoodfireAI. Registration is open and free to enter!
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Today we're launching the Alzheimer's Translation Challenge, a global AI competition to discover new therapeutic hypotheses for Alzheimer's disease. At its core is a new 150M cell atlas of neurons, astrocytes, and microglia across different genetic backgrounds under combinatorial perturbations, with multi-modal readouts. The data will be made available through the AD workbench, Hugging Face and Prima Mente's modeling platform. The challenge is led by @PrimaMente and @AlzData in collaboration with @nvidia, @huggingface, @nebiusai, Talisman Therapeutics, @UltimaGenomics, @cellanome, @PrimeIntellect, @GoodfireAI, and @boltz_bio. In 1906, Alois Alzheimer described a new disease of the brain. After 120 years of progress, we still don't fully understand what drives this disease. We want to change that. Participants will use the dataset to build AI models, assessed through a series of evals from general benchmarks to more complex tasks. Top teams will be shortlisted, and their experimental hypotheses tested in Prima Mente's wet lab. Teams win when their hypotheses demonstrate the predicted molecular and functional effect.
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I’ll be in Zurich tomorrow and Friday. If you’re interested in the Boltz models and would like to join our team or explore a partnership with Boltz, please reach out. It would be great to meet while I’m there.
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I’ve signed this letter alongside leaders from some of the UK’s best frontier technology startups, calling on the government to end restrictive employment practices that hold back our science and technology ecosystem. 🧵
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1/ Today we’re launching an open letter calling on the government to end unfair restrictions that stop Britain’s best switching jobs or starting companies. UK AI companies that have raised $5bn agree: our best should be free to start and scale. 🧵 @downingstreet @biztradegovuk
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Looking forward to this hackathon on Friday in Zurich co-organized with AI4Science Zurich and @merckgroup! I'll be around helping and brainstorming with teams, I'm excited to hear a lot of cool ideas! Sign up! luma.com/xrohmwdd
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We're excited to announce that @pas_saro, co-founder of @boltz_bio, will be delivering the keynote for #MoML2026! 🎟️ Only 10% of seats remain — register now to secure your spot: moml.mit.edu/
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Since releasing BoltzMol-1 a couple of months ago, we've seen exciting successes with several partners. Today we're sharing another example from our scientific team: a new case study led by @GSmithOfficial on Werner helicase (WRN), a highly dynamic & difficult cancer target 🧪🧬
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Boltz retweeted
boltz.bio -> boltz.com ; expanding beyond pharma
Excited to announce our partnership with @dsmfirmenich to bring @boltz_bio's latest AI models to the discovery and design of new scent and flavor molecules! 🧪
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Boltz Bio’s goal is to put frontier AI in the hands of every scientist working to understand and design the molecules that shape our world. Expanding beyond pharma, @boltz_bio partners with @dsmfirmenich to use these tools to create new flavors and fragrances.
Excited to announce our partnership with @dsmfirmenich to bring @boltz_bio's latest AI models to the discovery and design of new scent and flavor molecules! 🧪
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