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Nine years. Same conviction. Fund 5.
Gradient | $220M Fund 5
Gradient has been investing in AI since 2017. Announcing our fifth fund: $220M to back the next generation of AI founders at pre-seed and seed.
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Today marks a big milestone for @CollectiveFin
We secured $100M in financing to power the future of solo business.
We are entering a new era of entrepreneurship, one where the size of your ambition is no longer limited by the size of your team. AI is making it possible for a single person to build what once required an entire company. The next generation of great businesses will look radically different from the last.
With AI, we are realizing our purpose faster than ever - setting solopreneurs free to do what they love.
Deepest thanks to our members, team, and investors — new and existing — for supporting us as we build that future for America's 32 million solo businesses.
It's Day 1. Time to build.
@darian314, @VL, @miluntesovic, @gc, @iamjakestream, @pitdesi, @ABaumGates, @SelinaTroesch, @apartovi, @aplusk, @gokulr, @topherc, @scottbelsky, @pbronner, @levie, @nikesharora, @emilmichael, @eladgil, @lennysan, @fintechjunkie, @bonatsos
Collective has raised $100M to build the future of solo business.
We’re building the AI-native financial OS that gives every Business-of-One the back office of a much bigger company.
Thank you to our members, our team and our investors.
Read the full announcement: collective.com/blog/collecti…
As well as our CEO Hooman Radfar's blog post: collective.com/blog/100m-to-…
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Max and Taieb from @verahealthai are featured in WSJ VC today, talking about their global expansion!
Give it a read (h/t @ychernova)
wsj.com/pro/venture-capital/…
Gradient retweeted
1/ Today @CollectiveFin announced they have raised $100M to scale their Full-Stack AI solution for accounting, payroll, and taxes for solo-entrepreneurs nationwide. We @GradientVC bet on @hoomanradfar at the pre-seed and never imagined reaching this milestone!
collective.com/blog/collecti…
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. @katmdavis included me in this story on Anthropic's ambitious drug development plans axios.com/pro/biotech-deals/…
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Today, we're excited to announce that we have raised $10 million in funding and officially launched Sava Trust Company, an AI-native, modern trust company chartered in Nevada, open to clients and their attorneys & advisors nationwide.
Our funding was led by @GradientVC, with participation from @ycombinator, @svangel, @Max, @orangecollectv and @SurgePointCap.
For too long, trust administration has relied on manual processes, disconnected systems, and complex fee structures. Establishing a trust can take weeks or months, with limited visibility for families and their advisors over the life of the trust.
With Sava, we're building a better way.
youtube.com/watch?v=yR2bV3KT…
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We're excited to lead @savatrust's $10M seed round at @GradientVC with participation from @ycombinator @svangel @Max @tomerlondon! @nimit and team are bringing AI to the process of trust administration, funds flow, and compliance. They're also now fully chartered in Nevada. Sign up today!
axios.com/pro/fintech-deals/…
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Vera announced their Series A today. Thrilled to have led their first round of funding
Now, over 800K doctors are using Vera as part of their clinical practice
Up to 1 in 4 doctors in some countries
Special thanks to Daniel for all of the encouragement along the way
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Excited to announce @infisical's $40M Series B at $600M valuation led by @eladgil with participation from Y Combinator, Gradient, Pace Capital, Gallery Ventures, and others!
With new security exploits making headlines every week, security is quickly becoming a top priority for every team and company. AI is only accelerating this trend, making vulnerabilities easier to discover and exploit while introducing new security challenges as agents become increasingly sophisticated actors.
Today, Infisical provides security infrastructure with the core spanning secrets, certificate, and privileged access management. We've also launched Infisical Agent Vault, a new product enabling developers to build secure AI infrastructure where credentials are brokered to agents instead of given directly to them. This is the start to what we believe to be a core infrastructure primitive to be included in every harness engineering effort, giving agents access to needed services and enabling them to work effectively wherever they run.
With this funding round, we're doubling down on our ambition to make Infisical the security infrastructure platform for the agentic era. We want to live in a future where technology is secure by default, and we'll be relentless in our pursuit of making that future a reality.
As for the team, we're growing; we're a group of ambitious people who care deeply about craft, take ownership, and move fast.
Everyone here is a shark, and we're looking for more people who share our thirst for challenge and sense of urgency. If you're up for this kind of challenge and want to help secure the next generation of software infrastructure alongside an exceptional team, we'd love to have you join us.
We're hiring: infisical.com/careers
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Congrats @infisical on their $40M Series B led by @eladgil 🚀
Psyched to be the lead seed investor @GradientVC the leading platform for agent security!
We’re excited to announce we have raised a $40M Series B!
This next round of funding lets us continue to strengthen our secrets, certificate, and access management products.
We'll also expand the capabilities of Agent Vault, so engineers adopting AI agents can give them access without handing over the underlying credentials.
Thank you to @eladgil, @GradientVC, @ycombinator, and our other investors, as well as our customers, community, and team for helping us get here!
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💰Firstwork has raised $15 million in a Series A round led by @EarlybirdVC.
techfundingnews.com/firstwor…
LegionVC, Deel Ventures, and existing investors @GradientVC and @ycombinator joined the round. @SomaCapital, @468Capital and Houghton Street Ventures also participated.
#ai #hrtech #ustech #startups #funding #investment #innovation #vcfunding #technology
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Thrilled to be leading Firstwork $15m Series A alongside @GradientVC, Legion VC, Deel Ventures, @ycombinator and many great angels.
We couldn't be more excited to to be in business with Vardhan Kapoor, Shubham Choudhary and the rest of the Firstwork team.
Firstwork is going after what we believe to be one of the biggest markets in applied AI: frontline workforce operations. They're already processing tens of millions of actions and reducing the time it takes workers get to their first shift from days to minutes.
This is only the beginning, the ambition is much bigger.
@EarlybirdVC
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While hundreds of billions have been spent teaching AI to manipulate words and generate videos, ASI builds AI systems that can manage and control critical physical infrastructure - where there is zero margin for error.
Today we announced our $325M Series C to scale America’s Engine: the automated nervous system keeping the country running.
Respan OSS Gateway: the last AI gateway you ever need.
Because it can connect anything: LLMs, images, video, realtime voice, and MCP tools like web search and long-term memory, all through one endpoint. Each one is just a plugin you switch on.
Against LiteLLM on the same machine:
- 0.08 ms vs 5.9 ms added latency (78x less)
- 61,062 vs 1,348 requests/s with 50 in flight (45x more; LiteLLM on 14 workers)
- 33 MB vs 494 MB memory (15x less; LiteLLM on 1 worker)
Fully written in Rust. MIT/Apache-2.0.
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At @GamowLabs, we are committed to solving rare disease. This means understanding the clinical impact of >9B possible mutations in the human genome.
Computational models like @GoogleDeepMind AlphaGenome, @arcinstitute Evo2, and @biohub ESM3 serve their purpose, but the only way to accomplish our mission is through large-scale collection of experimental data on variant effects.
The only way to collect these data is through robotic labs like ours, which historically have required deep expertise in automation engineering to scale, limiting velocity.
To solve this problem, we are building frameworks to enable AIs to drive our lab robots and just unveiled our first eval showing that we have some work to do!
Can frontier AI agents run a robotic wet lab?
We built LabRobotBench to test how they operate equipment, manage timing, and recover interrupted experiments. LabRobotBench allows models to steer a simulation based on our real wet-lab setup in Boulder, CO!
The best model tested, GPT 6.1 Sol, scores a 46% on our benchmark.
Improving on LabRobotBench implies better robotic control and spatial awareness, as well as biological reasoning.
read more in our latest blog post: gamowlabs.com/lab-robot-benc…
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Huge congratulations to @AirSpaceIntel on raising $325M at a $3B valuation led by @sparkcapital @Citadel @MeritechCapital! We’re thrilled to have led the pre-seed @GradientVC from the beginning and continue to be blown away by @pbuckendorf and team 🚀
bloomberg.com/news/articles/…
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Congrats @gigsdotcom on being named to @TIME’s Best Inventions of 2026 alongside @Starlink for connectivity! time.com/collection/best-inv…
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Back-to-back robot shipments to New Zealand and India this week — have fun in your new homes, Feather!
Congrats @labelbox on raising $100M!
Today we’re announcing our Series E.
We’ve raised $100M+ led by Infinitum Partners. We believe every company will soon run on agents that learn from their own work.
- For frontier labs, Horizon provides RL environments that teach frontier models to do real work.
- For enterprises, Recursion brings managed agents into the apps your teams already use, improving with every run.
labelbox.com/blog/labelbox-s…
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Fragment is automating commerce.
We think there are millions of businesses that haven't been invented yet. Not because folks lack imagination, but because it's too hard to build the financial systems that run them. Fragment removes that constraint.
Today, people run companies. With Fragment, they'll run on their own.
fragment.dev/v2
Gradient retweeted
Nice coverage of @GamowLabs from the @GradientVC portfolio in the Gemini 4 launch!
"Researchers at Gamow Labs used Argon to analyze de-identified genomes from newborns with rare developmental lung disorders. In one case, Argon pinpointed a chromosomal rearrangement that routine software missed for years, and explained why it went undetected. On private Gamow Labs evals derived from real clinical and lab data, Argon topped on RareBench (57% on assistance with rare-disease diagnosis) and LabBench (52.2% on wet-lab reasoning). These advances point to faster diagnosis for families facing rare conditions."
blog.google/innovation-and-a… @GoogleDeepMind























