Research Fellow, Uni of Bham, UK. Immunology, virus and cancer.
Joined February 2012
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Alex Dowell retweeted
1/ Our preprint on immune responses of kids to #SARSCoV2 #Omicron is online
Top line: Primary Omicron infection induces poor antibody responses in unvaccinated kids, but robust T cell responses which will protect against severe #COVID19 in the future🧵
👉biorxiv.org/content/10.1101/…
Don't understand rational, surely aSy where likely hood of false POS is highest is exactly where PCR should confirm. Sympto even if not Covid still not bad to isolate. Surely this just risks healthy people being stuck at home, making short staffing worse!
UKHSA has confirmed that the requirement for asymptomatic people testing positive on lateral flow to do confirmatory PCR will be suspended - from Jan 11 in England - devolved administrations possibly sooner.
Early Christmas present having this finally come out, thanks to everyone that helped make this possible @Meg_Butler96 @jmzuo73 @VivaldiBham @ShamezLadhani @paulmos63832199 nature.com/articles/s41590-0…
Alex Dowell retweeted
🆕A new study by #UKCIC researchers from @UniBirmingham found that 98% of people aged 80+ who had 2 doses of the Pfizer #COVID19 vaccine produced a strong antibody immune response
Read more on our website👉uk-cic.org/news/dual-dose-pf…
Alex Dowell retweeted
The contribution of T cells to the SARS-CoV-2 response remains an important and unresolved question. Moss and colleagues examine T cell and antibody kinetics in a large cohort of patients with COVID-19 and find robust and durable T cell responses rdcu.be/cgobr
Alex Dowell retweeted
Alex Dowell, @low_helen, Paul Moss and colleagues @unibirmingham find that PD-1 is imprinted on #cytomegalovirus-specific CD4+ T cells and attenuates Th1 cytokine production whilst maintaining cytotoxicity.
buff.ly/3v7ofjI
Alex Dowell retweeted
Prof Van Tam showing the backbone that we have desperately needed to see over the past week
“In my opinion the rules are clear and they have always been clear...they are for the benefit of all...and they apply to all”
Please RT if you agree with him
Just had an email saying you're cost for credit card use REDUCED, so you have to decrease cashback. Highlights the complete shambles nationwide have become thought you were the best 12mths ago now near the worst! @AskNationwide
Losman et al EglN prolyl-4-hydroxylases needed by IDH1 TET2 mutants for myeloid transformation, @Kxh879
