Assistant Prof @uwgenome. Evolutionary dynamics in viruses, bacteria and cancer. she/her @alisonfeder@mstdn.science
Seattle, WA
Joined May 2014
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State-dependent evolutionary models reveal modes of solid tumour growth, now published!
nature.com/articles/s41559-0…
Accompanying News & Views:
nature.com/articles/s41559-0…
Huge congrats to lead author @MayaLewinsohn! Check out her pre-print thread for key takeaways!
Excited to share the first preprint of my PhD with @trvrb, @nicfelm, and @AlisonFeder! We detect boundary-driven growth by analyzing patterns in tumor trees. biorxiv.org/content/10.1101/… 1/13
Alison Feder retweeted
Our paper on the evolution of structural variation at the amylase locus is out today in Nature! nature.com/articles/s41586-0… congrats to co-first authors @joanocha @NicolasLou10 @davidebolo93 @Raveancic & Alma Halgren, co-corresponding author @erikgarrison
Alison Feder retweeted
Join us! The Machado Lab at @Cambridge_Uni is looking for an enthusiastic RA to be a core member of the team and lead the lab's data generation efforts, seeking to understand how tumour and immune cells co-evolve and contribute to cancer progression. jobs.cam.ac.uk/job/47922/
Alison Feder retweeted
Genome Sciences is pleased to announce that Dr. Saori Sakaue and Dr. William DeWitt have accepted our offers to join the department as assistant professors!
gs.washington.edu/
Alison Feder retweeted
Beyond thrilled to announce that I will be starting my research group at Genome Sciences at the University of Washington @UW next spring💫💫My dream place to do genetics & genomics, and such an exciting timing with a lot of new technologies and large-scale datasets emerging! (1/)
Genome Sciences is pleased to announce that Dr. Saori Sakaue and Dr. William DeWitt have accepted our offers to join the department as assistant professors!
gs.washington.edu/
If you're still building your must-visit agenda for the poster session today at #SMBE2024, don't miss Iris Jia's (@tongqiujia) poster at position 44 showing her spatial dissection of lung bacterial persistence through a novel therapy!
Getting ready for #SMBE2024!
Looking forward to learning about #evolution, sharing my work, and meeting you all! See you in Puerto Vallarta!
Alison Feder retweeted
Getting ready for #SMBE2024!
Looking forward to learning about #evolution, sharing my work, and meeting you all! See you in Puerto Vallarta!
Thanks for this nice summary, @sociovirology! Was really fun to get to share awesome work led by @epidememeology, and in collab with @evokerr!
To round off the day, @AlisonFeder talking about dominant drug targeting in poliovirus infection #SocialViruses
Alison Feder retweeted
Go @MayaLewinsohn & @AlisonFeder & all!
"The Prize Committee awarded Honorable Mention to: State-dependent
evolutionary models reveal modes of solid tumour growth, Maya A. Lewinsohn,
Trevor Bedford, Nicola F. Müller & Alison F. Feder, Nature E&E (2023)." isemph.org/Omenn-Prize
Alison Feder retweeted
Congratulations to Feder Lab undergraduate researcher Dylan Clark for being awarded the Thomas Sedlock Icon Scholarship!
expd.uw.edu/scholarships/sto…
Alison Feder retweeted
#TeamMassSpec We're recruiting postdocs to work on new methods to map proteome remodeling due to chemical perturbations, aging, development, and more! If you're interested, see the job posting:
ap.washington.edu/ahr/positi…
and some of the lab's projects: schweppelab.org/projects
Alison Feder retweeted
Really excited to work with @oligopain and @Keribackus on this super exciting project!
We are so thankful to the WM Keck Foundation for supporting this high risk, high reward idea!
Alison Feder retweeted
A new paper published in @MolBioEvol shows that "#HIV populations in people with higher viral loads also have higher rates of viral recombination" which "enables the exchange of genetic information across strains of the virus & drives HIV’s evolution." newswise.com/articles/increa…
Excited to share the published version of this in @MolBioEvol!
Elena Romero developed an approach to quantify recombination from longitudinal short read sequencing, and applied it to measure differences in recomb rate in HIV pops with low and high VL.
academic.oup.com/mbe/article…
Rapid recombination is an important driver of HIV intra-host evolution. Because recombination requires that multiple viruses co-infect a cell, Elena Romero and I wondered if high viral loads increase HIV's recombination rate.
tl;dr: we think they do!
biorxiv.org/content/10.1101/…
Much gratitude to the editor and 3 reviewers for their helpful suggestions. Published version has expanded suite of validation on simulated data and application to additional in vivo data.
Also very cool to be in the MBE 40th anniversary issue! academic.oup.com/mbe/issue/4…
Measles is normally acute & self-limiting, but in rare cases it can enter the CNS and cause fatal encephalitis (SSPE). In a collab with the Cattaneo lab & led by Iris Yousaf (@VIris__) and Will Hannon, we reconstructed the genetic events accompanying MeV brain colonization. 1/
So excited to share my first author publication! 😁 In this unprecedented work, we recreated the history of measles virus evolution in human brain in collaboration with @AlisonFeder and Will Hannon 😊
dx.plos.org/10.1371/journal.…
In sum, really grateful to get to work with Iris and Will, Roberto Cattaneo at the Mayo clinic, Ryan Donohue and others! Check out the paper in @PLOSPathogens: journals.plos.org/plospathog… and see a nice press release here: newsnetwork.mayoclinic.org/d… 14/14