Brie Schmidt

@iSeeRacist Please expose this person who thinks that Black people are garbage. See the last screenshot for the final blow.

@RacismDog Please repost this racist who obviously thinks Black people are the scum of the earth.

#dermpath #pathology #dermatology Recent case I had of cutaneous involvement by known granulomatosis with polyangiitis. These were photos I shared with the clinician who was concerned for infection.

3) IHC to confirm (🧦10 and PRAME). I let out an audible gasp when I got saw them, but was also very relieved that I didn’t go down the tubes with this one (I had great training from @MightyDermPath)! Got the PRAME after the 🧦 for re-excision feasibility purposes.

2) Where is the disruption? It’s not at the DEJ like one would see in an interface process. It’s INTRAEPIDERMAL (unzippering). Remember melanocytes lack desmosomes=no adherence Also, see how jumbled and grey the epidermis is? Another clue.

1) Another land mine of a case. TRUST YOUR EYES AND TRAINING. 70 y.o 👩 upper arm. “NUB vs BCC” #dermpath Looks like a BLK, right? What is a big clue that it’s NOT!

I had one, too!

This is a CK5/6 (of course I also got a PAS which was neg for fungi). Look @ how that material lights up! This is keratin-derived amyloid. Since there’s minimal epidermal change, I decided “c/w macular amyloid” (vs lichen).

I believe we can. Now, let’s look on high-power. What’s going on? How would you describe the papillary dermis? What’s your ddx and which stain(s) should you get?

#dermpath for trainees. Middle aged adult, elbow. “Ddx dermatitis vs psoriasis” What is your low-power impression? Can we exclude psoriasis already?