@BarbBauerCT

Science Research Specialist at CaaMTech. Advancing the knowledge and therapeutic uses of #psychedelic and non-psych natural compounds. #prodrugs #Cats love me.

caam.tech
Joined January 2019
  • Tweets392
  • Following1.1K
  • Followers3K
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Remembering Albert Hofmann on #BicycleDay! #LSD #psychedelics psychedelicreview.com/5-fast…
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Are #psychedelic medicines the reset for chronic pain? Preliminary findings and research needs 👇 sciencedirect.com/science/ar…
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Out now! Potential non-5-HT receptor targets of various #psychedelic tryptamines #Psilocybin-like effects and potency of 4-PrO-DMT in mice consistent with reports of its subjective effects 5-HT1A activity influenced 5-HT2A mediated HTR pubs.acs.org/doi/10.1021/acs… @ACSBioMed
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Structure–Activity Relationships for Psilocybin, Baeocystin, Aeruginascin, and Related Analogues to Produce Pharmacological Effects in Mice: loom.ly/-26TjX4
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Barb Bauer retweeted
CaaMTech@CaaMTechInc15 Nov 2022
Psilacetin is More Potent than Psilocybin: @CaaMTechInc, @NIDAnews, @usonainstitute, @ResearchUGent, @UMassD and @UWyonews researchers directly compared #psilocybin with understudied #magicmushroom molecules, and synthetic analogs such as psilacetin caam.tech/psilacetin-is-more…
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This was truly an amazing team effort by many folks from @usonainstitute, @CaaMTechInc, @christophestove, Manke lab, Hulley lab, and NIDA IRP DDRU. Keep an eye out for many more publications from us investigating the #pharmacology of #psychedelics !
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Barb Bauer retweeted
CaaMTech@CaaMTechInc22 Sep 2022
New paper by @CaaMTechInc @marilyn_naeem @BarbBauerCT @UMassD @AndrewChadeayne! 4-HO-DiPT has been proposed as a more clinically-optimized alternative to #psilocybin #psychedelic #science #chemistry #crystallography caam.tech/caamtech-creates-t…
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BREAKING: DEA Withdraws Proposal to Schedule 5 Psychedelic Tryptamines The challenge was led by co-counsel Matt Zorn and @calyxlaw for @TactogenInc and @MindstateDesign, with many others involved. This is a remarkable and unprecedented outcome.
Graham Pechenik@graham_pechenik22 Jul 2022
5 psychedelic tryptamines, kept off schedule I? DEA scheduling proceedings—terminated: “DEA is withdrawing the proposed rule…canceling the public hearing & terminating the pending hearing proceedings” Unprecedented outcome—a result of extraordinary lawyering by Matt Zorn 1/2
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The Doors of Expression: LSD Alters Epigenetics and Protein Induction psychedelicreview.com/the-do… #psychedelics #science

The Doors of Expression: LSD Alters Epigenetics and Protein Induction

Psychedelics have demonstrated the potential for rapid, dramatic, and enduring therapeutic effects in people with psychiatric disorders as well as in animal models of these conditions. However…

psychedelicreview.com
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Barb Bauer retweeted
ACS_Omega@ACS_Omega19 Jul 2022
▶️ Synthesis, Structural Characterization, and Pharmacological Activity of Novel Quaternary Salts of 4-Substituted Tryptamines 👥 Grant C. Glatfelter, David R. Manke & coworkers go.acs.org/1H7 @UMassD @NIDAnews @CaaMTechInc #Pharmaceuticals #SAR #CNS
Synthesis, Structural Characterization, and Pharmacological Activity of Novel Quaternary Salts of 4-Substituted Tryptamines

ALT Synthesis, Structural Characterization, and Pharmacological Activity of Novel Quaternary Salts of 4-Substituted Tryptamines

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On the shoulders of giants indeed. #Shulgin #psychedelics @CaaMTechInc #psychedelicresearch benzinga.com/markets/cannabi…
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Hot off the press. Researchers tested quaternary tryptammonium analogs at 46 receptors and transporters. No affinity for 5-HT2A but SERT stood out in binding affinity and SAR testing. #psychedelics #tryptamines #psychedelicscience #psychedelicresearch pubs.acs.org/doi/10.1021/acs…

Synthesis, Structural Characterization, and Pharmacological Activity of Novel Quaternary Salts of...

Abstract. Aeruginascin (4-phosphoryloxy-N,N,N-trimethyltryptammonium) is an analogue of psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine) that has been i

pubs.acs.org
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A creative strategy for producing #5-MeO-DMT and other potentially beneficial #psychedelic compounds found in #toad secretions. 🐸Further research will help determine if usable quantities can be produced. @HamiltonMorris #psychedelicscience biorxiv.org/content/10.1101/…

Incilius alvarius cell-based synthesis of 5-MeO-DMT

There is growing interest in the therapeutic potential of 5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine) for psychiatric disorders. While 5-MeO-DMT can be chemically synthesized, the parotoid gland...

biorxiv.org
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We shall not cease from entourage effecting And the end of all our entourage effects Will be to arrive where we started And know the entourage effect for the first time.
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Are you interested in the #chemistry of the #psilocybin derivative #baeocystin found in #magicmushrooms? CaaMTech has solved its crystal structure! @CaaMTechInc journals.iucr.org/e/issues/2…

The crystal structure of baeocystin

The crystal structure of the `magic' mushroom natural product baeocystin is reported for the first time.

journals.iucr.org
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Hallucinating Long After the Trip is Over: HPPD – Part 2 psychedelicreview.com/halluc… #psychedelics #science

Hallucinating Long After the Trip is Over: HPPD - Part 2

Potential causes, risks, and ongoing research for Hallucinogen Persisting Perception Disorder (HPPD).

psychedelicreview.com
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Hallucinating Long After the Trip is Over: HPPD – Part 1 psychedelicreview.com/halluc… #psychedelics #science

Hallucinating Long After the Trip is Over: HPPD - Part 1

An overview of the symptoms of Hallucinogen Persisting Perception Disorder (HPPD), how it differs from flashbacks, and how common it might be.

psychedelicreview.com
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Our recent paper in @npp_journal re SARs for cannabinoid-like effects of 5F-MDMB-PICA and 5F-pentylindole analogs in mice is featured as the NIDA IRP paper of the month 🙌😎 👇 irp.drugabuse.gov/featured-p…

Structure-activity relationships for 5F-MDMB-PICA and its 5F-pentylindole analogs to induce...

Structure-activity relationships for 5F-MDMB-PICA and its 5F-pentylindole analogs to induce cannabinoid-like effects in mice

irp.nida.nih.gov
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Psychedelic science opportunity🚨 We at @JHPsychedelics are hiring a postdoc who will work with me & Roland Griffiths. Having gone through the postdoc program myself, I can vouch for the the excellent scientific training and wonderful people at the lab. Please share widely!
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