ALT Figure 1. Change in 6-Minute Walk Distance through Week 24. The line graph shows the observed mean changes from baseline in 6-minute walk distance (in meters) in the sotatercept group (solid triangles) and placebo group (solid circles) with 95% confidence intervals (indicated by I bars). Walking distance was recorded at prespecified trial visits (i.e., week 0 [baseline], week 3, week 12, and week 24) during the first 24 weeks of the trial. The data shown are for patients with available data (observed) over time. The imputed median changes from baseline at week 24 for the prespecified and post hoc analyses are plotted as open symbols (open triangle for sotatercept and open circle for placebo). The prespecified and post hoc imputed medians are shown as open symbols with solid and dashed lines, respectively.