London based data analytics company that enables at least 6 fold higher clinical success rates and shortens development life cycles by at least 4 years
London, England
Joined April 2020
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Biological intelligence (BI): a biology first approach that de-risks and accelerates preclinical and clinical drug discovery and development without deep learning steps associated with artificial intelligence (AI).
Learn more about #BiologicalIntelligence➡️linkedin.com/pulse/biologica…
BRAINCURES LTD retweeted
Happy to share BRAINCURES @BraincuresLTD's cancer case study. See lnkd.in/eF62uSKt to learn how neuroscience and biological intelligence open new treatment avenues for oncology indications
🧵To mark World Alzheimer's Month, we present how our foundation model can navigate over 270 thousand Alzheimer's linked publications to identify and prioritize highly networked hub targets that carry high predicted preclinical/clinical success rates. See lnkd.in/eHCnfAvZ
linkedin.com/posts/how-to-va… highlights how BRAINCURES @BraincuresLTD's synaptic plasticity powered foundation model can turn Insilico Medicine @InSilicoMeds' TargetBench outputs for Parkinson's disease into actionable intelligence for high success preclinical and clinical investment
BRAINCURES LTD retweeted
BRAINCURES @BraincuresLTD proprietary targets and connectivity/hub rules enable the prioritization of high scoring druggable targets for Parkinson's disease that were prioritized by experts brought together by @MichaelJFoxOrg
linkedin.com/posts/braincure…
BRAINCURES LTD retweeted
🧵Can AI do scientific research? Billions are pouring in to find out by @AndrewE_Dunn @endpts and Programming biology: next-gen AI firms raise billions to design better medicines by @RealEndptsMel @NatureBiotech with comments from @biogerontology @joshim5
linkedin.com/posts/krzysztof…
BRAINCURES LTD retweeted
The BRAINCURES Discovery Engine prioritization of 229 Parkinson targets identifies 34 BDE targets, 11 BDE hubs, 2 BDE masters. Additionally, 83 of 229 community-led targets have hub protein properties. See michaeljfox.org/grant/target… for more on @MichaelJFoxOrg's Targets to Therapies
BRAINCURES LTD retweeted
@BraincuresLTD virtual phenotypic screening to accelerate the Drug Prioritization of Disease Modification Trials in Parkinson’s Disease: The International Linked Clinical Trials Initiative-iLCT by Richard Wyse @CureParkinsonsT, @ScienceofPD, @BrundinPatrik
linkedin.com/posts/braincure…
🧵12 Years of Drug Prioritization to Help Accelerate Disease Modification Trials in Parkinson’s Disease: The International Linked Clinical Trials Initiative
Drug Repurposing for #Parkinsonsdisease: The iLCT experience by @ScienceofPD, Wyse, @BrundinPatrik
linkedin.com/posts/krzysztof…
BRAINCURES LTD retweeted
🧵 The @BraincuresLTD Discovery Engine (BDE) foundational model leverages proprietary targets, compounds and connectivity rules to prioritize known or novel targets/drugs that have a high probability of preclinical/clinical success for Parkinson's disease
linkedin.com/posts/braincure…
BRAINCURES LTD retweeted
🧵Brain Awareness Week 2026: A Trillion Dollar Challenge that is a Hard Pill to Swallow for Pharma and Venture Capital linkedin.com/posts/krzysztof…
#BrainAwarenessWeek
1) Pharma ins and outs neurology linkedin.com/pulse/pharma-in…
2) Neuroscience pipeline tracker linkedin.com/pulse/neuroscie…
BRAINCURES LTD retweeted
A key review on the synaptic tagging and capture hypothesis behind learning and memory
Making memories last: the synaptic tagging and capture hypothesis by @Neuroger Richard Morris reviews how new behavioral studies have experimentally translated the hypothesis to learning & the consolidation of newly formed #memories
pubmed.ncbi.nlm.nih.gov/2117…
nitter.gq/BrainPrize/status/1416…
🧵Altered hippocampal LTP/LTD is a major driver in aging. BRAINCURES' prioritization of age-associated gene expression in the human and rat dentate gyrus reveals 17 highly novel human-rat synaptic plasticity targets for brain health and healthy longevity
linkedin.com/posts/braincure…
🧵The BRAINCURES Discovery Engine (BDE) prioritizes 66 of 748 schizophrenia genes as BDE Targets by applying biological intelligence to "The druggable schizophrenia genome: from repurposing opportunities to unexplored drug targets" by Lago and Bahn. See linkedin.com/posts/krzysztof…
Applying the BRAINCURES Discovery Engine (BDE) Target, Hub and Master prioritization to 141 aging clock drug targets compiled by Chen et al highlights that investigational compounds linked to 19 BDE aging clock hubs have a high clinical success probability
linkedin.com/posts/krzysztof…
BRAINCURES LTD retweeted
The biological intelligence that powers the @BraincuresLTD Discovery Engine (BDE) platform leverages novel biology insights and target connectivity to deliver a 69 to 97 percent Phase III Clinical Failure elimination rate. Apply BI to get more out of foundation models/LLMs/agents
🧵 The BRAINCURES Discovery Engine-BDE can help you drive biomarker discovery and prioritization. See linkedin.com/pulse/biologica… to discover how our biological intelligence approach can increase your preclinical and clinical success rates while reducing/refining/replacing animal use
🧵 The BRAINCURES Discovery Engine-BDE can help you drive biomarker discovery and prioritization. See linkedin.com/pulse/biologica… to discover how our biological intelligence approach can increase your preclinical and clinical success rates while reducing/refining/replacing animal use
BRAINCURES LTD retweeted
🧵The @BraincuresLTD Discovery Engine provides a novel approach to further experimental validation and extension of the TxGNN foundation model for clinician-centered drug repurposing. Discover how biological intelligence enables a new era in drug discovery
linkedin.com/posts/braincure…
🧵Can we bring more cures for brain diseases by 2030? Two Steps Forward, One Step Back: The Long Road to Success in Central Nervous System (CNS); Trends in Neuroscience Drug Discovery and Development; Pharma Ins & Outs Neurology provide excellent insights linkedin.com/pulse/pharma-in…
BRAINCURES LTD retweeted
@brittanytrang reports that @EliLillyandCo’s TuneLab includes 18 models, 12 aimed at predicting small-molecule drug properties and six for assessing whether antibodies are amenable to further development. Possibly more qualitative (in vitro/vivo) statistics are behind the paywall
Lilly is opening up its proprietary AI models to biotech companies that want to use them to jumpstart their science. trib.al/uvhRT5S
BRAINCURES LTD retweeted
How do you build a winning hand in drug discovery? Like poker, success depends not just on a strong starting hand but on how the game unfolds. The challenge now: how do we scale insights to discover even more winning hands?
—Robert Plenge, EVP @bmsnews
linkedin.com/posts/robert-pl…
BRAINCURES Discovery Engine-BDE Neuromap Navigates LLM Generated Outputs to Increase Success Rates in Parkinson's disease. Of note, 7 LLMs-BioGPT, Grok3, DeepSeek R1, Claude Opus 4, OpenAI’s GPT4o, GPT4.1 & GPT-o3-failed to identify 425 of 632 BDE Targets linkedin.com/posts/braincure…
