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Developmental physiology lab investigating the molecular mechanisms of how mother and child communicate during pregnancy, and the consequences when it goes awry

King's College London
Joined June 2023
Photo by Marika Charalambous Lab (@CharalambousLab)Photo by Marika Charalambous Lab (@CharalambousLab)Photo by Marika Charalambous Lab (@CharalambousLab)Photo by Marika Charalambous Lab (@CharalambousLab)Photo by Marika Charalambous Lab (@CharalambousLab)
Our latest preprint. @L_Lampe, @clarenewell24 and colleagues figured out how metamorphosing #Drosophila avoid drying out. The larva makes a lipid barrier of hyper-long hydrocarbons (>C27 and longer) and stores it in the fat body until needed by the pupa. tinyurl.com/3keukxsz
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Have you heard of ‘pregnancy brain’? Recent research shows that changes in the brain with #pregnancy correlate with successful bonding to the infant! See: nature.com/articles/d41586-0… Created with support from @CamUniEngage and @britsocimm 🙏🏻 #whum #womenshealth
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Marika Charalambous Lab retweeted
We have two new faculty opportunities at QMUL, part of a £3.2M investment by @Barts_Charity to develop genomic and epigenomic liquid biopsy analyses for diagnostics and research applications. More details here: qmulepigenetics.com/jobs Please RT abundantly
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More good news from the lab! Felicitations to the fabulous @RishaAmarsi who successfully passed her PhD viva last night.
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Congratulations to our amazing Dr @LillinaVignola for her successful thesis defence yesterday!
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Marika Charalambous Lab retweeted
Weight gain during nutritional rehabilitation post-childhood malnutrition may influence the associations between adulthood desaturases activity and anthro-cardiometabolic risk factors sciencedirect.com/science/ar…
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Marika Charalambous Lab retweeted
The prevalence of suboptimal affinity binding sites within enhancers creates a vulnerability in genomes whereby single-nucleotide changes that optimize affinity, even slightly, can be pathogenic. doi.org/10.1038/s41586-023-0…
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Marika Charalambous Lab retweeted
Interested in women’s health? Looking to undertake a MSc? Then look no further! Our MSc in women and children’s health covers key topics in reproductive and maternal health, pregnancy, and infant health using novel teaching and assessment approaches kcl.ac.uk/study/postgraduate…
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Marika Charalambous Lab retweeted
Very happy to see our last paper of 2023 is out: The loci of many genes with redundant function (including paralogs) are in close proximity in 3D #Chromatin_loops. We show that such gene-gene loops often involve genes that cross-regulate each other’s expression. 1/4
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Fantastic story about how a primate-specific trancription factor regulates repetitive sequences that control embryonic pancreas fate.
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Marika Charalambous Lab retweeted
🏅We're delighted to announce Dr Matthew Higgs as the winner of the 2023/24 Bruce Cattanach Prize. Funded by Mouse News Letter Ltd, this prize is awarded annually for an outstanding PhD thesis related to the use of non-human in vivo animal models genetics.org.uk/8-november-2…
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Interesting idea, especially coupled to the knowledge that histones and DNA also can act as a major sink for intermediary metabolites.
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Marika Charalambous Lab retweeted
Staring at the Sun - researchers have never before had such detailed views of our nearest star Read the full story: nature.com/articles/d41586-0… This gif shows a snake-like disturbance of relatively cool plasma rippling across the Sun
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This Thursday, an afternoon of discussion about how knowledge of developmental mechanisms can inform us about disease.
Less than two weeks until our next #MedicineAtTheCrick on Thursday 2 November! You can still book tickets for this free event, hosted by @AlexGouldLab and featuring a range of speakers discussing how embryonic development influences adult disease. crick.ac.uk/whats-on/medicin…
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Marika Charalambous Lab retweeted
My main PhD work is now out as a preprint 👇
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Cool paper about genomic imprinting and parenting behaviour from the Isles lab @ProfAntIsles
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