Christopher Gayle

Here to say the @PhorosCloud AI is really good 👍

Over the past few months, Anthropic scientists have engaged in deep research partnerships with six organizations developing new medicines. We've also begun drug discovery efforts of our own. In doing so, we’ve learned much more about how Claude can support the many stages of drug development. In this blog post, we share some early results from these efforts, and describe how this work fits in with our wider ambitions in the life sciences. anthropic.com/research/early…

Just spent the last 7 days on the front lines of the vulnpocalypse fending off an active cyber attack on one of our products. Some thoughts: - Software factories are going to be required equipment for everyone. There’s just no way to keep up with the pace of highly automated adversaries without one. - We were lucky because we had spent the last few months getting our software factory running well. It is nice to have for product development but proved to be absolutely essential this week. - At the minimum you need to have a coding server in the cloud pre-provisioned with read only access to all your logs and all the services you depend on for observability. With that in place you are a prompt away from reasonably good situational awareness, ongoing monitoring with loops, and ability for coding agents to validate fixes against your actual, observed attack patterns. - Shared coding server also unlocks multiplayer incident response where everyone can see every session and jump in as needed. Sharing session links that can be forked is much higher bandwidth than re-explaining things. - You don’t need to be Ramp/Stripe/Uber scale to have a working software factory in the cloud. We are a team of 3. Ours is built with an @opencode server (thanks @thdxr!), a forked version of compound engineering optimized for automated workflows (thanks @kieranklaassen!) and a multiplayer agent in slack that handles crons (we have our own harness but pick your favorite here). - To get our software factory up and running well, we had to stop all new product development for ~6 weeks and just focus on getting the validation systems working that enabled us to reliably shipping PR without human code review. This felt very painful in the moment but was totally worth the eventual speedup in velocity. - KYC for @AnthropicAI & @OpenAI cyber programs is now easy and quick (at least for defensive access), but a day felt like a lifetime this week. Submit your app now before you really need it. - Getting Mythos access unlocked a deeper level of analysis that helped us shift from reactive mitigation to proactive patching. Wish we had done this a few weeks earlier. Get started now!

there is no moat

We’re releasing a broad range of new mathematical results produced by an internal frontier model. We’ve been consulting with the independent Advisory Group on Mathematics and Artificial Intelligence at the Institute for Advanced Study, and we have drawn on their advice and public recommendations to inform how we release these results. github.com/openai/math

A French engineer who lives quietly in Paris has spent 30 years writing software that the entire internet now runs on without knowing his name. He wrote the code that streams every YouTube video, every Netflix show, every TikTok clip. He wrote the code that runs the virtual servers underneath AWS, Google Cloud, and Microsoft Azure. He calculated more digits of pi than anyone in history. He has no Twitter. He has no marketing. He just keeps shipping. His name is Fabrice Bellard. Here is the story, because almost nobody outside the systems programming world knows what one man has built. Fabrice was born in 1972 in Grenoble, France. He studied at École Polytechnique, the top French engineering school. He never went to Silicon Valley. He never built a startup empire. He just wrote code. In 2000 he started a project called FFmpeg, an open-source multimedia framework for encoding, decoding, and streaming video. He was 28. The project did one thing nobody else had done well. It handled every video and audio format that existed, in one library, on every operating system. He led it himself for years. Today FFmpeg is the invisible engine of the internet. YouTube uses it. Netflix uses it. VLC uses it. Chrome and Firefox use parts of it. Every Android phone, every iPhone, every smart TV, every video editing tool you have ever touched runs FFmpeg somewhere underneath. If you have watched a video on a screen in the last 20 years, Fabrice's code processed it. He was not done. In 2003 he started QEMU, a machine emulator and virtualizer. He wrote it solo until version 0.7.1 in 2005. QEMU lets you run any operating system on any other operating system. It became the foundation of modern virtualization. KVM, the Linux kernel hypervisor, runs on top of QEMU. Every major cloud provider, AWS, Google Cloud, Microsoft Azure, IBM Cloud, runs virtual machines on infrastructure built around it. The Quick Emulator is the most cited piece of cloud infrastructure code on Earth. He kept going. In 2001 he won the International Obfuscated C Code Contest with a small C compiler that grew into TCC, the Tiny C Compiler. TCC can compile and boot a Linux kernel from source in under 15 seconds. In 2004 he calculated the most digits of pi ever computed at the time, using a personal desktop computer and an algorithm he derived himself called Bellard's formula. In 2011 he wrote a complete PC emulator in pure JavaScript that runs Linux in your browser, a project called JSLinux that engineers still cannot believe is real. In 2019 he released QuickJS, a small but complete JavaScript engine that fits where V8 cannot. In 2021 he released NNCP, a neural network based lossless data compressor that immediately took the lead on the Large Text Compression Benchmark. Then he turned his attention to large language models. He built TextSynth Server, a web server with a REST API for running LLMs locally. He released ts_zip and ts_sms, compression utilities that use language models to compress text and short messages at ratios traditional algorithms cannot reach. He released TSAC, a very low bitrate audio compression system. In December 2025 he released Micro QuickJS, a new JavaScript engine for microcontrollers, separate from QuickJS, designed for environments with almost no memory. Fabrice co-founded a telecom company called Amarisoft in 2012, where he serves as CTO. Amarisoft builds 4G and 5G base station software used by carriers and labs around the world. He has been running it for over a decade while continuing to ship personal projects from his own home page at bellard dot org He has no Twitter. He has no Instagram. He gives almost no interviews. His personal website is a flat list of projects with no styling, no fonts, no marketing copy. Just titles and links. A quiet French engineer who never moved to Silicon Valley wrote the code that quietly runs the internet. He is still shipping.

When you look back, you’ll wish you’d just done the long-term version of everything.