In LQT2, pa ent-specific modeling iden fied persistent L-type Ca2+ current as a key arrhythmic amplifier and prospec vely guided nifedipine rescue #Epeeps @JohnGiudicessi @MJAckermanMDPhD ahajrnls.org/4hLaCkt
Electrophysiologist-Led Deep Sedation for Pulsed Field Ablation of Atrial Fibrillation Using a Bipolar Contact Force Focal Catheter: The DEEP-PFA Randomized Controlled Trial @paulzei @HanFengGHD #Epeeps ahajrnls.org/4e4Vo7z
AI-ECG may offer a new window into AF recurrence after PFA – tracking risk before ablation and recovery in the first 90 days #AFib #AIECG #PFA @msardana_MD @noseworthypeter @JF_RodriguezR #Epeeps ahajrnls.org/4icLRxF
Uni-LVA and LVEF independently predict end-stage HF at NICM VT ablation. A 3-point risk score identifies highest-risk patients for advanced HF therapies #Epeeps @DrMatthewHyman @ericazado @rdschaller @Yuichiro_Sagawa @Dr_Markman @drhbkmd @ArianAfzalian ahajrnls.org/4yA4od8
NEK7 activates the NLRP3 inflammasome in atrial cardiomyocytes and contributes to postoperative AF, constituting a potential therapeutic target for AF @naliphd #Epeeps
doi.org/10.1161/CIRCEP.126.0…
Standardized Spark-Pattern Cut-Mode Electrosurgical Bailout Workflow for Difficult Left Bundle Branch Area Pacing Lead Advancement: Procedural and Follow-Up Outcomes From a 15-Patient Case Series #Epeeps doi.org/10.1161/CIRCEP.126.0…
Meta-analysis shows lifestyle and risk factor modification clinics reduce AF recurrence after ablation, AF hospitalization and improve quality of life #Epeeps
doi.org/10.1161/CIRCEP.126.0…
Severe or Benign Sinus? AI reclassifies 30-second single-lead ECGs around documented AF recurrence with AUC 0.86. @chanholim @HanFengGHD @AmitabhCPandey @nmarrouche #Epeeps
doi.org/10.1161/CIRCEP.125.0…
In 783 adults with Marfan syndrome, sustained VT/VF occurred in 9.5% & clustered with NSVT, lower LVEF, MR, surgery, & LGE @CNKanaan @masry_hicham #Epeeps doi.org/10.1161/CIRCEP.126.0…
CircEP retweeted
📣Calling all #AHFTC Fellows!📣
@CircHF is proud to launch the 2nd year of the journal's free educational webinar series for current & past AHFTC fellows
📌9 live virtual sessions
📌New topic each session
📅Start Date: November 18, 2026
🔗Learn More: ahajournals.org/circheartfai…
≥6 minutes replaces 30 seconds for AF/AFL/AT recurrence duration as a recommended effectiveness AF endpoint for clinical trials of AF Ablation @JonPicciniSr @EP_mom1 @ed_gerst @atulverma_md @AndreaRussoEP @KLThomasMD @mvperez92 @tjaredbunch @Wanginnovate ahajrnls.org/4rM1PCo
Pulse Field Ablation: From Bench to Blueprint: Mechanistic Insights and Device Engineering and Early Clinical Translation @luigidibiasemd @ElaineWanMD #Epeeps ahajrnls.org/47umrFz
Virtual heart models linked stable PS with stable DF to greater low-voltage burden, steeper restitution, and higher 1-year recurrence after ablation #Epeeps ahajrnls.org/4hy7lUr
CircEP retweeted
📣 #Stroke Bridge Seminar: Advancing Stroke Intervention: From Device Innovation to Clinical Practice
🗓️ Tuesday, October 6, 2026, 12:00-1:00 PM PDT | 19:00-20:00 UTC
🌟 Speakers: @JeremyHeitMDPHD & Matthew J. Gounis
🌟 Hosted by @Chenhsbbb
📎Register: ahajrnls.org/47p4Izo
New variable loop circular catheter waveform, Sequence 2, reduces PFA time 20.6s→3.8s and shows to be safe and effective in a preclinical model #Epeeps @True_EP @JonHsuMD @rahul3000 @JasperZouMD @JorgeERomero.MD @luigidibiasemd ahajrnls.org/46KjS1V
The key glycolytic regulator PFKFB2 is lost with HFpEF, and its loss promotes repolarization prolongation, Ca2+ mishandling, and arrhythmogenesis #Epeeps @stavrosstavrak1 @ChiFungLeePhD @harold_kylene @Ken_Humphries ahajrnls.org/46KcweV
New swine model combines ECMO + Impella to sustain VF without ischemia, enabling high fidelity heart mapping for arrhythmia research #Epeeps @attabehfar @f_delcarpio @nicktanCV @RC_Ward @EzzeddineMD @ikramhaqmd @DrDeese99 ahajrnls.org/4iJmF2K
This pooled analysis showed high agreement and predictive ability of 6-month effectiveness endpoint with 12-month endpoint for AF ablation trials @drjasonandrade #Epeeps ahajrnls.org/4yJcTCc
A high durable isolation rate of the pulmonary veins or roof/posterior wall block may be achieved provided a sufficient PFA application number is performed #Epeeps @SergeBoveda @gergoare @POllitrault @egandj @BeneytoDr ahajrnls.org/4AkOd4F
After PFA, SCL incidence was similar across 4 strategies, but lesion burden differed—suggesting binary assessment may miss key differences #PFA #AtrialFibrillation #CardiacEP #MRI @TakaseTetsuro #StrokePrevention #Epeeps ahajrnls.org/4hdLZLO



















