Retrotransposons, nucleolar biology, and more! @berkeleyMCB (account run by trainees)
Joined February 2024
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Collins Lab retweeted
Beyond thrilled to present our O-MAP—now *published* @naturemethods (!!!)
O-MAP is a powerful new method for biochemically "dissecting" the subcellular microenvironment around an RNA of interest, using off-the-shelf parts and standard manipulations. 🧵
nature.com/articles/s41592-0…
Collins Lab retweeted
Vertebrate retrotransposons are the future of gene therapy. But how do they insert their genes? 🔥🔥
Thrilled to present part 2 of my postdoctoral work with @NogalesLab @CollinsRNPLab @berkeleyMCB where we investigate this using #CryoEM and transgene insertion in 🧪 and cells!
Collins Lab retweeted
Harnessing eukaryotic retroelement proteins for transgene insertion into human safe-harbor loci - @CollinsRNPLab go.nature.com/3utPERu
Collins Lab retweeted
Groundbreaking study by the @CollinsRNPLab demonstrating the use of R2 proteins from multiple species for genome editing!
Today starts a new era of genome engineering!
We use RNA-only delivery to safely and efficiently deliver genes of interest to the human genome! @CollinsRNPLab @berkeleyMCB
A thread 🧵:
nature.com/articles/s41587-0…
Collins Lab retweeted
Did you ever wondered how "jumping genes" actually jump? 2 papers now published in @Nature show the 3D structure of the enzyme responsible for human LINE-1 retrotransposon (links 👇). Congrats to the authors !
A @NatureNV to recap the many new insights nature.com/articles/d41586-0…