Dr. Gideon Coster's Genome Replication lab @ICR_London. Studying what happens when DNA becomes its own enemy...
London, England
Joined March 2021
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🧬 The Coster Lab 🔬 retweeted
How do we decide which research applications to fund?
We rely on the expertise and impartiality of our advisory committees – and we’re currently seeking members worldwide.
Find out more about the role and how to apply 👇
wellcome.org/grant-funding/g…
🧬 The Coster Lab 🔬 retweeted
An exciting preprint on the role of nicks in GAA repeat expansions just landed on @biorxivpreprint today! A 🧵.
biorxiv.org/content/10.1101/…
🧬 The Coster Lab 🔬 retweeted
Please RT: The Walter lab at Harvard seeks computational biologists to extend our work using AlphaFold to find new protein-protein interactions. Contact [email protected]
biorxiv.org/content/10.1101/…
predictomes.org/
🧬 The Coster Lab 🔬 retweeted
Just over a week left to apply for the postdoctoral position in our lab. We are an international and supportive bunch, focusing on biochemistry and structural biology of DNA replication. Happy to chat/answer your questions. Have a look and RT pls.
📢Research Fellow wanted to create & contribute to the creation of knowledge by undertaking research specified by BBSRC research grant awarded to @AgaGambus to investigate function of DONSON during DNA replication initiation. shorturl.at/ghnGX
🧬 The Coster Lab 🔬 retweeted
We are looking for DNA replication enthusiast to join our group as a postdoctoral researcher. If you are into biochemistry, cell biology, structural biology in replication and damage, please get in touch, or apply - the link below. Closing date 9th November. RT pls
📢Research Fellow wanted to create & contribute to the creation of knowledge by undertaking research specified by BBSRC research grant awarded to @AgaGambus to investigate function of DONSON during DNA replication initiation. shorturl.at/ghnGX
🧬 The Coster Lab 🔬 retweeted
*Job alert*
We are looking for a chemistry postdoc to work on targeting G-quadruplex DNA in a BBSRC funded project with @VijayChudasama_ and @BakerGroupUCL
It will be a lot of fun- please share!
@School_Pharmacy
@UCLChemistry
ucl.ac.uk/work-at-ucl/search…
🧬 The Coster Lab 🔬 retweeted
🧬Scientists have uncovered key mechanism linking #DNA replication to #Cancer.
This contributes to a better understanding of how cancer develops. It may also open the door to new treatment approaches that could be effective across multiple cancer types⬇️
icr.ac.uk/news-archive/scien…
ALT Photo of Dr Gideon Coster, Team Leader of the Genome Replication team at the ICR, next to the following quote: “certain sequences in the human genome lead to secondary structures that are sufficient by themselves to halt replication”
🧬 The Coster Lab 🔬 retweeted
How do physiological DNA secondary structures affect genome stability?
In vitro reconstitution by @CosterLab @ICR_London shows physiological #G4 or iM #quadruplex formed during #replication stall eukaryotic #replisome by inhibiting leading strand synthesis
embopress.org/doi/full/10.15…
🧬 The Coster Lab 🔬 retweeted
If you are interested in an update on G-quadruplex (G4) structure resolution @QuadruplexPape1, check out our review in the special issue of DNA repair on genome maintenance @DNArepair. Many thanks to Koichi Sato @KoichiS0813 who did most of the work. authors.elsevier.com/sd/arti…
🧬 The Coster Lab 🔬 retweeted
Hi all. Two fully funded four year postdoc positions to study DNA replication initiation using human proteins. Please check out the ad and contact me if you want more info. Closing 30 September.
crick.ac.uk/careers-study/va…
crick.ac.uk/careers-study/va…
🧬 The Coster Lab 🔬 retweeted
Job Alert📢📢
We are recruiting postdocs in Protein Biochemistry bit.ly/45vrx1A & Cell Biology bit.ly/45ijcOX to join our lab @BiochemOxford. Join us to tackle the next big challenges in the Wnt signalling field in a fun, collaborative & supportive environment!
🧬 The Coster Lab 🔬 retweeted
Two weeks left to apply for a 3-years post-doc position in my lab. get in touch if interested and apply !
jobs.ac.uk/job/CZT658/postdo…
🧬 The Coster Lab 🔬 retweeted
Thoughtful and excellent perspective on the issues raised by the unexpected closing of the CPR in Copenhagen by the Novo Nordisk Foundation. Its by our international SAB under the leadership of Angus Lamond. Out in EMBO Reports now.
embopress.org/doi/epdf/10.15…
🧬 The Coster Lab 🔬 retweeted
Last few days to apply for a research assistant position to develop better #AAV constructs for #Crispr Cas9 expression for #GeneEditing for #HuntingtonsDisease, #DM1 and more!
Join us at the @UKDRI at Cardiff Uni!
Closes May 14th. Apply here: tinyurl.com/2p8bmcdw
🧬 The Coster Lab 🔬 retweeted
New preprint! In this work, @kamyaryzd and @srivsesh , both postbac fellows in the lab, study the binding of endogenous proteins, the iMab antibody, and a small molecule to >10k i-motifs from the human genome! biorxiv.org/content/10.1101/…
🧬 The Coster Lab 🔬 retweeted
We're hiring a bioinformatician!
#longread sequencing of expanded tandem repeats! #Huntingtonsdisease #myotonicDystrophy #GeneEditing
In Cardiff!
Contract until March 2028!
Closing date: May 2nd
tinyurl.com/bddbv3mw
Re-tweet!
ALT A schematic of how bioinformatics is magic.
🧬 The Coster Lab 🔬 retweeted
📢JOB ALERT!📢
We are recruiting 2 postdocs, protein biochemistry bit.ly/3KMhMDs, cell biology bit.ly/3L9rl0x and a RA/Lab manager bit.ly/3KKqxO9 to join our lab @BiochemOxford to study mechanisms of Wnt signalling at the cell membrane. Deadline May 16.
🧬 The Coster Lab 🔬 retweeted
Job alert!
We are hiring a #bioinformatician ! Contract until 2028! In lovely Cardiff!
Analyse and develop methods for complex DNA seq datasets - tandem repeats, SNPs, CNVs - using long read and single-cell sequencing.
Apply by May 2nd. Pls RT. krb-sjobs.brassring.com/TGne…
🧬 The Coster Lab 🔬 retweeted
A brilliant thread from @FoglizzoMartina. A bit delayed from me, but really happy to share our results. Led by superstar postdocs @DrHaydenB in Wilson lab and @FoglizzoMartina, a fantastic collaboration with the @zeqiraj lab.
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