Building a comprehensive, standardized knowledge repository of SARS-CoV-2 virus-host interaction mechanisms, guided by domain experts, based on published work.
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ALT FIGURE 3 Protein-pathway network of 69 changed pathways in COVID-19 patients. Pathways are shown as rectangles and the proteins present in a pathway are connected to the pathway node and shaped as circles. The pathway nodes visualize the heatmap of pathway activity change in COVID-19 patients from thyroid, lung, heart, liver, spleen, kidney and testis in that order. Blue indicates a lower pathway activity in COVID-19 patients (protein abundance distribution shifted to the left) and red indicates an increased activity (protein abundance distribution shifted to the right). Most of the pathways are highly connected with many proteins in common.
ALT An overview of the areas of focus of the C19DMap biocuration. Go to covid19map.elixir-luxembourg.org for an interactive version. Full list of diagrams and browsing instructions are available online at covid.pages.uni.lu/map_contents.
ALT List of 33 pathway updates in 2 hours by 8 group members.
ALT Figure 2 from the preprint, showing the structure and content of all COVID-19 disease maps.
ALT Figure 2 from the preprint, showing the structure and content of all COVID-19 disease maps.
