Paul Crichton (@CrichtonLab) header
Paul Crichton (@CrichtonLab) profile picture

Group leader, Norwich Medical School (UEA)... membrane proteins, mitochondria in health and disease, bioenergetics

Norwich, England
Joined March 2013
Photo by Paul Crichton (@CrichtonLab)Photo by Paul Crichton (@CrichtonLab)
Paul Crichton retweeted
This year the Xmas Bioenergetics meeting is in York! It's a friendly one-day meeting around anything to do with bioenergetics. Please retweet and share
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Excited to share our work on how ECF #transporters use ATP binding to charge a molecular spring and tune the #membrane shape to expel membrane-embedded substrate-binding proteins from the docking site into the membrane. #cryoEM #Biochemistry #MDsimulation rdcu.be/dhJvy
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Delighted with our latest work published @JAMAInternalMed led by @justvick #WIC @uniofeastanglia @NNUH on Risk Factors for Long Covid. Reduce the risk by getting vaccinated & HEALTHY LIFESTYLE #vaccines #work Full article: jamanetwork.com/journals/jam… VACCINES WORK @medtwitter #epeeps
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A huge thank you to our scientists from UEA who taught the year 5s about growth, reproduction and energy🔬They especially enjoyed the explosion… more photos to follow …
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Amazing work by Vasso & colleagues @Mitocarriers mapping the substrate binding site of the mitochondrial ADP/ATP #carrier by exploiting elegantly substrate-induced shifts in thermostability assays doi.org/10.1038/s41467-022-3… @STavoulari @thecarrierking @MRC_MBU
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Our paper is in press! The human mitochondrial pyruvate carrier (MPC) was a hard nut to crack. We provide critical insights on the protein composition and inhibitor binding to facilitate drug discovery efforts. sciencedirect.com/science/ar…
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Paul Crichton retweeted
If you're an undergraduate medical student thinking of intercalating, come along to our Intercalation Evening on 25 November on West Campus to find out more. bit.ly/3bT0xiy
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Dr Justin O'Grady (@Justin_OGrady) will be on @BBCLookEast this evening with @BBCwestcott to discuss the new variants of #coronavirus and how scientists at the Quadram are mapping the spread of the virus in #EastAnglia through genome sequencing. 📺 Tune in from 6.30pm!
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Meet my neighbor Noreen. Proudly announced she got a XMAS 🎁 from 🎅 in the form of a @pfizer #VACCINE from @anasCUH_NHS. Posted with permission. BE LIKE NOREEN 😊 Please RT #covid #getavaccine @NHSMillion @exerciseworks @mmamas1973 @purviparwani @DrMarthaGulati @hvanspall @Hragy – at Cambridge, England
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Paul Crichton retweeted
Congratulations to four pioneering female members of our UEA community for awards in the Queen's Birthday Honours! 👏 Laura McGillivray, Prof Laura Bowater, Prof Gillian Schofield & Prof Amelia Fletcher; we're proud of all four of them. Read more here: uea.ac.uk/news/-/article/uea…
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Paul Crichton retweeted
"He demonstrates all that can be achieved in a scientific career and serves as a great example for all students at UEA today." Read about UEA grad Dr Michael Houghton, jointly awarded the Nobel Prize for Medicine yesterday for his life-saving work 🔬 bddy.me/36z1yep
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Paul Crichton retweeted
Say hello to 'Home' The weather might be turning, but you can still get outside & enjoy our campus during the day in this new social space. Find Home on the grassy area beyond the SU shop 🏠🍃 Remember, social distancing rules apply, & you must attend in groups of 6 or less.
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Paul Crichton retweeted
The Tate group @MRC_LMB is happy to contribute to our collective understanding of arrestin-coupling to #GPCRs. We present a #cryoEM model of the β1AR-βarr1 complex bound to formoterol, an arrestin-biased agonist, in nanodisc. @JGarciaNafria @arshukla nature.com/articles/s41586-0…
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Paul Crichton retweeted
Publicly accessible via SharedIt. rdcu.be/b40Ze
The Tate group @MRC_LMB is happy to contribute to our collective understanding of arrestin-coupling to #GPCRs. We present a #cryoEM model of the β1AR-βarr1 complex bound to formoterol, an arrestin-biased agonist, in nanodisc. @JGarciaNafria @arshukla nature.com/articles/s41586-0…
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Paul Crichton retweeted
Hundreds more people can be tested for #coronavirus every day in #Norfolk thanks to new kit from UEA's Medical School (@UeaMed) A huge thank you to @NNUH @EarlhamInst and @TheQuadram for their support 🙏 #ThinkingWithoutBorders #WeAreTogether ow.ly/aH3I50zmbZY
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Paul Crichton retweeted
Researchers at UEA have launched a project to 3D print ventilator parts, masks and other critical equipment to battle the #Covid19 virus. The project is being led @dr_aramsaeed and supported by @Ben_garrod: ow.ly/cBXA50yTgBj #ThinkingWithoutBorders #Coronavirus
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This is amazing - thank you! 💙
Technicians in our New Science Building are hard at work creating hand sanitiser gel for #NHS partners and we’re still keen to hear from any organisations who can share ethanol or bottling containers: ow.ly/BNzb50ySOm4 #ThinkingWithoutBorders #COVID19
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