Nodes of Ranvier

topical skincare tier list. 𝗦 𝗧𝗜𝗘𝗥 (essentials) > tazarotene cream: the undisputed king of anti-aging. a final form retinoid that binds to receptors for aggressive cell turnover. if you only run one topical for the rest of your life, make it this. > ghk-cu serum: a copper peptide that upregulates human genes across 31.2% of the genome. provides collagen, elastin & glycosaminoglycan synthesis. best combined with microneedling. > pure vitamin E oil: a healing antioxidant that halts lipid peroxidation caused by UV radiation & pollution. > korean SPF 50 PA++++ sunscreen: formulated with UV filters that defend against cellular dna damage & collagen degradation. 𝗔 𝗧𝗜𝗘𝗥 (𝗮𝗺𝗮𝘇𝗶𝗻𝗴) > grass-fed beef tallow: an ancestral moisturizer i use packed with vitamins (A, D, E & K). > azelaic acid: clears vascular redness & blocks hyperactive melanocytes. > niacinamide (vitamin b3): stimulates endogenous ceramide synthesis. > vitamin c serum: free-radical scavenger that assists collagen synthesis. 𝗕 𝗧𝗜𝗘𝗥 (𝗼𝗸𝗮𝘆) > estriol gel: reverses skin thinning locally on estrogen receptors. > standard OTC retinol: weak, inefficient two-step cellular conversion that completely fails to remodel deep tissue like tazarotene/tretinoin. 𝗖 𝘁𝗶𝗲𝗿 (𝗰𝗼𝗽𝗲) > rosehip oil: nourishing bodily oil yet oxidises too quickly to deliver real anti-aging results. > jojoba oil: great healing properties but greasy & overrated for facial skincare. 𝗗 𝘁𝗶𝗲𝗿 (𝗮𝗯𝘀𝗼𝗹𝘂𝘁𝗲 𝘁𝗿𝗮𝘀𝗵) > almost everything else. marketing gimmicks designed to do absolutely nothing for long-term skin architecture. recommended sourcing below. not medical advice.