Matt Bielski (@DefianceCEO) header
Matt Bielski (@DefianceCEO) profile picture

Founder, CEO @Defianceinvest ($11 Billion AUM) | Firefighter 🧑‍🚒| Autism Dad & Advocate | @YamoPharma Investor & Advisor

New York, USA
Joined October 2015
Congrats to the team 🔥
Defiance Quantum ETF has crossed $6 billion in AUM 🎉 Listed on the @Nasdaq, $QTUM is the first and largest US-listed pure-play quantum computing ETF. It offers direct exposure to the companies building the next computing paradigm, including IBM, D-Wave, Rigetti, and IonQ. $IBM $QBTS $RGTI $IONQ Learn More: defianceetfs.com/qtum/ Distributor: Foreside Fund Services, LLC. Investing involves risk and principal loss is possible.
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More CDS ETFs Filed • Defiance AI Infrastructure Credit Hedge ETF - $AICS • Defiance $CRWV Credit Hedge ETF • Defiance $META Credit Hedge ETF • Defiance $ORCL Credit Hedge ETF Eff: Jan 19, 2027 Fees: [tba] Exposure to the credit risk of underlying securities by buying protection through credit default swaps (CDS) that reference their debt obligations. Designed to gain in value when the market perceives the creditworthiness of those companies to be deteriorating. Notional amount of CDS positions at 5-10x of net assets. Filing: sec.gov/Archives/edgar/data/… #ETF #NewETF @defianceinvest
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Quantum
IBM $IBM JUST UNVEILED ITS MOST ADVANCED QUANTUM COMPUTER IN CHICAGO
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Matt Bielski retweeted
$IBM UNVEILS ITS FIRST QUANTUM COMPUTER IN ILLINOIS The IBM Quantum System Two, powered by Nighthawk, the most powerful quantum processor IBM has built, is now running at the University of Chicago's Hyde Park Labs. It will later move to the Illinois Quantum and Microelectronics Park on the former U.S. Steel site on Chicago's South Side, where it will anchor the National Quantum Algorithm Center. Illinois has committed $500 million to the park, including $200 million for a shared cryogenic plant, and IBM has pledged 750 jobs at its innovation center there.
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Crypto income ETF Filed • Defiance Coindesk Crypto Revenue Leaders ETF Eff: Jan 20, 2027 - Fees: [tba] Tracks the CoinDesk Revenue Leaders Index which is designed to measure the performance of up to ten crypto assets associated with blockchains or protocols that generate the highest on-chain revenue and use mechanisms to transfer economic value to token holders, with constituents weighted in proportion to their on-chain revenues over the preceding 180 days subject to a 40% cap. Filing: sec.gov/Archives/edgar/data/… #ETF #NewETF @CoinDesk @CoinDeskMarkets @defianceinvest
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Matt Bielski retweeted
🇦🇷 🇦🇷 Tesla Argentina!! 🇦🇷 🇦🇷
Llegamos a Argentina el 20 de Noviembre
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Nearly $2 billion authorized for autism research. So why are promising medications still struggling to reach clinical trials?
Nearly $2 billion authorized for autism research. So why are promising medications still struggling to reach clinical trials? The answer reveals a funding gap most families never hear about. Our latest Substack explores where public research funding goes, why private investment still matters, and what it takes to turn promising science into real answers. #AutismResearch #Autism #ClinicalTrials #L179 #asd
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🚨 Shield AI is acquiring radar maker Echodyne in a $5.3 billion deal, expanding its capabilities in counter-drone defense technology. The company is also raising $2.5 billion in financing at a $28.8 billion valuation, more than doubling its $12.7 billion valuation from March. bloomberg.com/news/articles/…
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Black Thursday 🩸
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Excited for this one
🎉 We're excited to announce the launch of Defiance Mag7 UCITS ETF on London Stock Exchange (ticker: $ MAGZ LN, £ MAGP LN), Deutsche Börse (ticker: € MA9S GY), Borsa Italiana (ticker: € MAGZ IM), and Euronext Paris (ticker: € MAGZ FP). This material does not constitute a marketing document. It is not an invitation to invest and is for educational purposes only. #MagnificentSeven #MAG7 #NewLaunch #ETF #Investing #HANetf
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The world's first AI hyperscalers ETF is live ☁️ $AIHY invests in companies building and operating the compute backbone of AI, targeting those that are scaling profitably rather than simply attached to the AI narrative: a substantial AI business, revenue growing faster than operating expenses, positive year-over-year revenue growth, and a positive gross profit margin. The Defiance AI Hyperscale Leaders ETF allows investors to express a view directly on hyperscaler earnings through a single ticker. Now trading on @NYSE. Learn More: defianceetfs.com/aihy
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Matt Bielski retweeted
Writing this in my personal capacity, but I have been flying these types of aircraft for more than 20 years, with over 8,000 hours, and have reasonable familiarity with how the charter world operates. I feel compelled to post after seeing commentary about the Lear 60 crash, from missile strikes to DEI to critiquing this poor woman’s final radio calls. That last part is what I find most troubling. She was the second-in-command (SIC), and while she was empowered to point out mistakes as part of good crew resource management, she was doing her job, communicating with ATC right to the end in a terrifying situation. She likely knew before many of those calls that she was going to die. I have heard final calls from friends, from military pilots with thousands of hours in fighter aircraft, and they are just as heartbreaking because they know the end is approaching. I understand the public interest given the footage and audio. But you do not know the aircraft’s maintenance history, whether there was a structural failure, if any failure was induced by turbulence, overspeed, or overcontrol, or everything happening in that cockpit. I am sure weather will be part of the investigation, but beyond that, it is speculation. The charter industry routinely hires commercial pilots very early in their careers to gain experience alongside an ATP-qualified captain before they move up to the airlines. She would still have the appropriate training, qualifications, and checkouts by an FAA examiner or designee. Let people investigate, learn, and share the facts. Be respectful to those who perished and the families who carry their memories. God bless them and their loved ones.
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🤹‍♀️My son Lev is profoundly autistic. The progress I’ve seen with Yamo’s investigational L1-79 is why I invested and became an advisor. Families deserve more options. I’m committed to helping fund the trials needed to find out whether this drug can help others. @elonmusk @realDonaldTrump @RobertKennedyJr @DrOz globenewswire.com/news-relea…
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Matt Bielski retweeted
"When I say the drug was life-changing, it was life-changing..for my 4yr old son Lev who is profoundly autistic" - Matt Bielski Defiance CEO (and issuer of $ASD) on Yamo Pharma's L1-79, a potential groundbreaking drug which is in phase 2 clinical trial but poised to be first FDA-approved therapy for autism, which 1 in 31 children are diagnosed with in US (incl my youngest son, so this segment def hit home. This is as emotional as ETF IQ gets, but really glad we could have this discussion) w/ @scarletfu @BloombergTV
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Matt Bielski retweeted
Miracle new 'Ozempic of autism' drug cured my son's worst symptoms... just days after taking his first pill: Breakthrough treatment poised to explode across globe as clinical trial leader says he 'almost fainted' at the results trib.al/lX1gux1
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*ANTHROPIC PUBLICLY FILES FOR NASDAQ IPO UNDER SYMBOL $ANT *ANTHROPIC $80.7B NET LOSS FOR SIX MONTHS ENDED JUNE 30, 2026
Introducing Defiance’s 2X Anthropic ETFs: $ANTC: 2X Long $ANTQ: 2X Short Built to seek 2X and -2X the daily move of Anthropic stock. Stay up to date: defianceetfs.com/anthropic-e…
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Matt Bielski retweeted
BREAKING: Anthropic reveals it is developing its own experimental drugs using Claude, targeting rare childhood diseases & various cancers.
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Matt Bielski retweeted
On this day in 2010: Tesla opened its first factory. It was an old GM-Toyota plant. Today, Tesla’s worth more than 5x GM and Toyota combined.
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Defiance Quantum ETF has crossed $6 billion in AUM 🎉 Listed on the @Nasdaq, $QTUM is the first and largest US-listed pure-play quantum computing ETF. It offers direct exposure to the companies building the next computing paradigm, including IBM, D-Wave, Rigetti, and IonQ. $IBM $QBTS $RGTI $IONQ Learn More: defianceetfs.com/qtum/ Distributor: Foreside Fund Services, LLC. Investing involves risk and principal loss is possible.
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We will never stop fighting to find real clinical solutions for the millions of children and families living with profound autism. Whether it is this specific therapeutic or the next, we must take bolder risks and direct capital toward late-stage drug development that can truly change lives. Consider this: Out of The National Institutes of Health (NIH) budget of roughly $47 billion dollars, hundreds of millions are allocated toward autism research each year, yet virtually zero federal funding reaches the most advanced companies entering Phase 3 trials. Early-stage discovery is critical, but translational medicine dies in the gap between lab research and commercial readiness. Innovative companies like Yamo Pharmaceuticals should not have to carry late-stage clinical risk entirely alone. Private equity continues to pour billions into standard ABA therapy franchises, while pharmacological breakthroughs targeting root biological challenges remain severely underfunded. Lev’s journey is our own, but what we witnessed firsthand altered our lives forever. It proved that real therapeutic progress is possible when we back science that aims higher. I will continue to invest my own capital and resources into this space, supporting teams willing to take on high risk, high impact therapeutics. Moving the needle at scale requires the entire community, including private investors, biopharma leaders, and federal agencies, to step up and fund late stage clinical trials that actually deliver.
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