Director at OerthBio, father of 3, biochemist, runner
Joined July 2021
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- Following70
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Sam Gattis retweeted
Big thank you to @BattlefieldLead and Colonel Kevin Farrell for an enriching workshop. Who knew long-ago decisions on the battlefield could have such relevance today?
#leadershipmatters #oerthlings
Sam Gattis retweeted
Interesting: label recombinant E3s on Cys w/ maleimide + linker + target binder, electroporate into cells, see if degradation ensues. Complementary to covalent fragment screens. Eye-opener was that a tagged CRL adaptor (SKP1) also led to degradation.
cell.com/cell-chemical-biolo…
Sam Gattis retweeted
SCOOP: An insanely well-funded company called Altos Labs is going after "rejuvenation" technology.
Yamanaka factors. Epigenetic clocks. CRISPR.
Offering academics $1 million salaries and more.
Investor rumor mill: Milner, Bezos, ARCH. Musk?
technologyreview.com/2021/09…
Sam Gattis retweeted
Our new review out on the Ligandability of E3 Ligases for Targeted Protein Degradation Applications by @bridgetbelcher & @carlcward in @BiochemistryACS that includes our aggregate chemoproteomic data for cysteines in E3 ligases! pubs.acs.org/doi/10.1021/acs…
Sam Gattis retweeted
Assessing target engagement using proteome-wide solvent shift assays biorxiv.org/cgi/content/shor… #bioRxiv