The NH Senate has again rejected Right to Try, shutting the door on patients seeking experimental treatments. A few state senators have decided that New Hampshire is closed for business to biotech firms offering frontier therapies. Here's what happened and our next steps. This term, a bipartisan majority of the state House passed HB 1734 and HB 1735: two bills to make New Hampshire the best state in America for experimental therapies. The bills were based largely on existing laws in Montana and Florida. Granite Bio Innovation—and the businesses and patients we support—helped build a coalition across every branch of elected state government to support these bills. We also worked for several months to build consensus in the Senate. Senators received calls from patients, businesses, investors, scientists, and healthcare providers supporting the bills. After Senator David Rochefort requested a long list of changes to HB 1734, the biotech firms involved agreed to every change. But these negotiations were not in good faith. Senator Rochefort abruptly decided he would not accept any version of the bills, and the Senate rejected both. The New Hampshire House then attached both bills to Senate Bill 504—this time with an even broader bipartisan vote of 197 to 145. Rather than negotiate a compromise, the Senate decided to fight this bill at any cost. Sadly, there is no pathway for making New Hampshire a commercial-scale hub for experimental therapies until the composition of the NH Senate changes. Until then, Granite Bio Innovation will continue to support New Hampshire's patients and innovators in the following ways: • Shaping other areas of state legislation in a way that facilitates frontier biotechnology in New Hampshire. • Advocating for state and federal regulatory policy that allows New Hampshire's biotech ecosystem to flourish. • Serving as a nexus for innovators and pro-biotech policymakers, including through an annual conference in August and by providing resources to healthcare providers. We are grateful to the many New Hampshire officials who have embraced the state's promise as a biotech hub, including @NHHouseGOP leadership, Governor @KellyAyotte, Mayor @JayRuais, and those senators who supported Right to Try on the Senate floor. We are especially grateful to @NHSpeaker for sponsoring the amendment to SB 504 and to Representatives @KesselringSteve and @cole4nh for their tireless leadership on these bills and courageous stand for patients in need. With a biotech revolution approaching, a US state will soon become a hub for experimental therapies. The only question now is which one.