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One of my fav lab hacks: store your E coli pellets in freezer bags. They freeze in 5 mins, resuspend in under 3 mins (in the bag!), take up less freezer space, and don't waste conical tubes!
Haven't been to active on this platform lately but here goes!
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Excited to share our latest preprint!
biorxiv.org/content/10.1101/…
We developed a method to generate high-affinity binders against membrane proteins in their native-like environment!
🧪 #MembraneProteins #Nanobodies
Huge thanks to co-authors Hayley Knox @basicchemist & Brian Cho, mentors Barbara Imperiali & Karen Allen @kna6662, and everyone who made this possible!
Still amazed this worked so well. Check out the full preprint and let me know what you think!
#StructuralBiology #YeastDisplay #Science #CryoEM #NativeMP
@MITBiology @BU_Tweets
So glad this is out in final form! Check the thread below for an awesome story involving structure, bioinformatics, synthesis, and assay dev!
#glycotime
bsky.app/profile/gerg77.bsky…
GERG retweeted
Spacedust: de novo discovery of conserved gene clusters. Combining sensitive Foldseek structure search and conserved neighborhood detection to discover functionally-associated gene clusters in prokaryotic & viral genomes.
🚀github.com/soedinglab/spaced…
📄biorxiv.org/content/10.1101/… 1/6🧵







