Based at the University of Sussex, we are working on understanding motor neurone diseases to help improve diagnosis and lead to new treatments.
University of Sussex, England
Joined February 2019
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Delighted to share our latest paper 'Severe dynein dysfunction in cholinergic neurons exacerbates ALS-like phenotypes in a new mouse model'. Read at doi.org/10.1016/j.bbadis.202…
Funded by MND Association @mndassoc
Hafezparast Lab retweeted
🚀 Exciting new publication from the Hafezparast Lab! @ProfHafezparast
📄They explore how an ALS-associated TDP-43 mutation affects microglia-derived miRNAs after LPS stimulation.
Read the full paper here:
journals.biologists.com/dmm/…
#ALS #SussexRNA #RNA #Neuroscience
Delighted to share our latest @DMM_Journal paper 'The ALS-associated TDP-43M337V mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner'. Read at journals.biologists.com/dmm/…
Hafezparast Lab retweeted
#ResearcherSpotlight💡
PhD student Sarah Gornall is investigating whether small changes in a combination of several genes can lead to the development of #MND #ALS. 🧬
Learning more about genetics in MND could lead to new potential therapies.
Read more: mndassociation.org/research/…
ALT Person in a laboratory wearing a lab coat
Are you interested in discovering non-coding RNA biomarkers for early diagnosis of motor neuron disease? If yes, apply for a postdoc with us on a @LifeArc funded project @SussexNeuro @SussexLifeSci
jobs.sussex.ac.uk/job/af9d5c…
Hafezparast Lab retweeted
Our Sussex Neuroscience 4-year PhD Programme is open for applications! Deadline Feb 19th, for Sept 2024 entry. Brilliant community of students and supervisors, and a choice of >50 labs for rotations- come and join us by the sea! sussex.ac.uk/research/centre…
Hafezparast Lab retweeted
We have a fully funded @SoCoBioDtp studentship advertised, together with my wonderful colleagues @TheWangLab and @HafezparastLab. If interested, you can find out more here:
southcoastbiosciencesdtp.ac.…
Deadline: 8th January 2024
Just a reminder that you have one week left to apply for this position in our group! Why not come join us on the South Coast to investigate biomarkers for MND?
How would you like to come to @SussexLifeSci @SussexNeuro and work on a @mndresearch-funded project looking at identifying ncRNA biomarkers in MND using a clinical trial cohort? If that interests you, then come apply for a postdoc with us for two years!
sussex.ac.uk/about/jobs/rese…
How would you like to come to @SussexLifeSci @SussexNeuro and work on a @mndresearch-funded project looking at identifying ncRNA biomarkers in MND using a clinical trial cohort? If that interests you, then come apply for a postdoc with us for two years!
sussex.ac.uk/about/jobs/rese…
After seven years of incredible research into MND, Dr Greig Joilin is starting a new path as a lecturer. It has been an absolute pleasure to have him in my team & witness his exceptional talents & dedication to make a difference. Thank you Greig and all the very best for future!
Proud to share our latest @tandfonline paper “Aberrant Dynein Function Promotes TDP-43 Aggregation and Upregulation of p62 in Male Mice Harboring Transgenic Human TDP-43.” Investigates axonal transport in #ALS. Read it at doi.org/10.1080/21678421.202…
In work done by @EleniVChristof as part of her PhD, she investigated whether mice with mutations in both TDP-43 and dynein would cause TDP-43 cytoplasmic mislocalisation and protein aggregation, which although is a key ALS pathology, is not observed in most TDP-43 mouse models.
Hafezparast Lab retweeted
A great pleasure to supervise our fantastic Sussex Neuroscience PhD student Eleni Christoforidou @EleniVChristof and to celebrate her graduation with her. Many congratualtions Eleni @SussexNeuro @SussexLifeSci
Hafezparast Lab retweeted
Great opportunity to join our Neuroscience faculty (Research and Education Lectureship) at the University of Sussex: Deadline extended to August 15. sussex.ac.uk/about/jobs/lect…
Hafezparast Lab retweeted
Last night at the #ENCALS2023 poster session, the team caught up with a number of @mndassoc funded researchers!
Amazing to see so many of our #MND #ALS researchers presenting their work and making new connections! 👩🔬👨🔬
Here are just a few we caught on camera 📷
ALT Calum Harvey stood in front a poster
ALT Greig Joilin stood in front of a poster
ALT Sarah Roscoe stood in front of her poster
Hafezparast Lab retweeted
We've been catching up with @DrGreigJoilin & @hellychayts at ENCALS about their projects that were supported by the Foundation 🔬
Thank you both for your continued work in MND research and helping us to make our vision a reality.
And so our time at #ENCALS2023 comes to an end. A great few days of networking, sharing our work, learning about the exciting work being done everywhere else, and enjoying the sunshine and hospitality in Barcelona!
We are at #ENCALS2023 and ready to share some of the work that we have been doing over the last couple of years with three posters over the next two evenings!
And lastly, we have @DrGreigJoilin who is presenting his @MNDoddie5 and @mndresearch funded work looking to find prognostic and progression non-coding RNA biomarkers using a longitudinal results and has some promising results.
So please come along, see what we found and have a chat with us - we'll try to be there while trying to catch a look at all the other exciting posters at #ENCALS2023!