🇧🇷 Postdoctoral Fellow, University of Illinois at Urbana-Champaign/@BeckmanIllinois

Champaign, IL
Joined September 2020
New paper alert! 🚨 In this study we explored how interactions between the locus coeruleus (LC), basolateral amygdala (BLA), and the ventromedial prefrontal cortex (vmPFC) affect freezing behavior and extinction learning. 🧵(1/5) pnas.org/doi/10.1073/pnas.25…
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These results reveal a circuit mechanism by which LC–NE biases activity of BLA→vmPFC to generate a heightened fear state. The better understanding of this circuit may help explain stress-related impairment of fear extinction in disorders such as PTSD. 🧵(5/5)
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Thanks to all the amazing collaborators who made this work possible!
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Congratulations to the newly minted Dr. Hugo Bayer (@HugoBayer1 ) !! Great work and super cool story ! 🍾👏🥳🎉
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We looked at evidence from all sorts of fear memory reconsolidation studies and tried to determine what is known about the temporal dynamics of different systems that contribute to memory reconsolidation and persistence after recall.
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Most neurotransmitter systems and intracellular elements are most important during and immediately after memory recall, while others are more involved at later time points, especially those supporting long-term persistence mechanisms triggered by memory recall.
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Today, our 🐭lab celebrates 18 years — congratulations and a big thank you to members and alumni! @CristinaStern, @HugoBayer1, @Isabeus_,@Lgazarini
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📣 New Cai Lab paper in @CellReports! We show that a stressful experience can produce different types of memories! We also find that the basolateral amygdala (BLA) & ventral hippocampus (vHC) differentially contribute to these memories 🧠 cell.com/cell-reports/fullte… More ⬇️ (1/6)
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Hugo Bayer retweeted
Connectome: anatomy Network: a bunch of connected neurons circuit: a bunch of connected neurons PCA: beginner level magic Manifold: advanced magic neural dynamics: neural activity dynamical system: anything that changes attractor: stable state in neural activity
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🌟Review Alert! Excited to share our latest article, where we explore the effects of serotonergic #psychedelics and related substances (e.g., MDMA) on extinguishing and reconsolidating aversive memories, expressing fear/anxiety, and locomotion in rodents. authors.elsevier.com/a/1jq5G…
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Heading to Chicago for #SfN24 ? Come check out the awesome stuff happening in the lab! It is bright and early on Monday morning, so don't stay out too late :)
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Academic publisher Elsevier's profit margin compared to Apple, Google, and Microsoft Apple: 28% Google: 25% Microsoft: 34% Elsevier: 37% with a revenue of $3.9 billion. Elsevier's payment to academic authors and reviewers: $0
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These findings suggest that during the initial stages of *fear* memory consolidation, a trace that *opposes fear* is established in the IL, which is counterintuitive or perhaps paradoxical.
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The work continues, and I hope to understand more exciting things about IL and fear memory consolidation in the near future!
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