@IGH_MTP

Institute of #Human #Genetics dedicated to fundamental #research e.g. #genome dynamics, developmental #genetics, #epigenetics, molecular & cellular #pathology

 Montpellier, France
igh.cnrs.fr
Joined April 2017
  • Tweets2.5K
  • Following98
  • Followers1.4K
537Media
InstituteHumGenetics retweeted
ConstantinouLab@ConstantinouL16 May 2025
Our latest work "TopBP1 biomolecular condensates: a new therapeutic target in advanced-stage colorectal cancer" led by Laura Morano, is now out in @eLife! Huge thanks to our collaborators at @IGH_MTP & @ircm_mtl. And a special thought goes to Angelos. 🙏 doi.org/10.7554/eLife.106196

TopBP1 biomolecular condensates as a new therapeutic target in advanced-stage colorectal cancer

Pharmacological disruption of TopBP1 condensation impairs ATR signaling, promotes DNA damage and apoptosis, and enhances the efficacy of FOLFIRI chemotherapy in colorectal cancer.

elifesciences.org
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1 year ago we published that the connection between DNA replication stress and STING-IFN signaling regulates senescence. This work contributes to understanding autoinflammatory disorders, aging and cancers. @paserolab @IGH_MTP @ircaninstitute rdcu.be/etXpD
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👩‍⚕️ Femmes & Filles de Science 🔬🔭Conférence d'Isabelle Regner "Les stéréotypes: des biais cognitifs puissants" à l'occasion du 10e anniversaire de la Journée internationale des femmes & des filles de science 👩‍🔬👩‍💻 📅14.02.2025 à 12h30 📍 Campus Triolet 🔗 umontpellier.fr/agenda/les-s…
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InstituteHumGenetics retweeted
ecomnews_agenda
@ecomnews_agenda12 Jan 2025
📅#Montpellier : Les #Voeux2025 de @umontpellier et de son président @Philippe_Auge auront lieu ce 14 janvier.
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InstituteHumGenetics retweeted
CNRS Biologie@CNRSbiologie1 Jan 2025
🎉 Bonne année 2025 ! Toute l’équipe de @CNRSbiologie vous adresse ses meilleurs vœux pour cette nouvelle année. ✨ Que 2025 soit une année riche en découvertes et avancées en #biologie ! 🌱 📽️dailymotion.com/video/k6aa6g… @CNRS
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InstituteHumGenetics retweeted
CNRS 🌍
@CNRS1 Jan 2025
#BonneAnnée 🌟 Le @CNRS vous présente ses meilleurs vœux pour l'année 2025 ! #HappyNewYear 🌟 The French National Centre for Scientific Research (@CNRS) wishes you the very best for 2025!
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InstituteHumGenetics retweeted
Antoine Petit@antoine_petit_10 Dec 2024
C’est avec une grande tristesse que j’ai appris la disparition d’Alain Fuchs. Nous sommes nombreux et nombreuses à avoir apprécié son engagement et sa force de conviction qui ont été des atouts majeurs pour le CNRS. Chaleureuses condoléances à sa famille et ses proches.
CNRS 🌍
@CNRS10 Dec 2024
Le CNRS a appris avec une grande tristesse le décès d’Alain Fuchs, Président du CNRS de 2010 à 2017. Il a été une personnalité engagée au service de l’enseignement supérieur et la recherche en France. Le CNRS présente ses condoléances à sa famille et ses proches. 👉 cnrs.fr/fr/presse/deces-dala…
There's a new version of this post
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#ENTERO2024 happened almost a month ago & marked our 1⃣st step in addressing early-onset digestive cancer cases! Check out the📽️ recap video below to see some highlights from the event. ⬇️ 👏Thank you to everyone who joined us to discuss this important topic. @EU_Health
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InstituteHumGenetics retweeted
CNRS Biologie@CNRSbiologie6 Nov 2024
#ResultatScientifique 🔎 | Traduction oui, mais compartimentée 🤝 @CNRS @CNRS_OccitaniE @umontpellier @IGH_MTP ✍️ Martine Simonelig 📕 @NatureComms | buff.ly/4feOlrs buff.ly/3YQdFyq
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InstituteHumGenetics retweeted
ConstantinouLab@ConstantinouL29 Oct 2024
We are pleased to inform you that the meeting “From Genome Instability to Cancer: A tribute to Angelos Constantinou” that will take place in Carry-Le-Rouet from March 10th to March 13th 2025 is now open for registration on the link: tribute2angelos.fr/page/home…
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InstituteHumGenetics retweeted
Moreaux Jérôme@moreauxjerome10 Sep 2024
Congrats Caroline👍. Happy to share this collaborative work with the group of Thierry Fest. link.springer.com/10.1007/s1… @IGH_MTP @umontpellier @CHU_Montpellier @InstUnivFr @CarnotCALYM

BHLHE41, a transcriptional repressor involved in physiological processes and tumor development

Cellular Oncology - BHLHE41 is a nuclear transcriptional repressor that belongs to the basic helix-loop-helix protein superfamily. BHLHE41 expression tends to be restricted to specific tissues and...

link.springer.com
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InstituteHumGenetics retweeted
Moreaux Jérôme@moreauxjerome27 Aug 2024
Congrats @Charles_Herbaux 👍 A case of refractory IgG4-related disease successfully treated with daratumumab and lenalidomide pubmed.ncbi.nlm.nih.gov/3918… @IGH_MTP @CHU_Montpellier @umontpellier

A case of refractory IgG4-related disease successfully treated with daratumumab and lenalidomide -...

A case of refractory IgG4-related disease successfully treated with daratumumab and lenalidomide

pubmed.ncbi.nlm.nih.gov
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InstituteHumGenetics retweeted
Moreaux Jérôme@moreauxjerome19 Aug 2024
Happy to have participated in this collaborative work with the groups of Martin Villalba and @gcartron : FCGR3A F158V alleles frequency differs in multiple myeloma patients from healthy population tandfonline.com/doi/full/10.… @IGH_MTP @CHU_Montpellier @InstUnivFr @umontpellier

FCGR3A F158V alleles frequency differs in multiple myeloma patients from healthy population

FCGR3A presents a single nucleotide polymorphism at location 158 (V/F), which affects its binding to the fragment crystallizable (Fc) of antibodies (Abs). FcγRIIIa-158 V allotype has the highest af...

tandfonline.com
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InstituteHumGenetics retweeted
Moreaux Jérôme@moreauxjerome2 Aug 2024
Thrilled to share that our research is featured on the cover of Blood. Integrative single-cell chromatin and transcriptome analysis of human ... sciencedirect.com/science/ar… @IGH_MTP @InstUnivFr @umontpellier @CHU_Montpellier @FacultemedMPL @CarnotCALYM
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Molecular mechanisms of transgenerational epigenetic inheritance go.nature.com/40mNtL0 #Review by Maximilian H. Fitz-James & Giacomo Cavalli @CNRS @umontpellier @IGH_MTP Free to read here: rdcu.be/dBBQc
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InstituteHumGenetics retweeted
MRI@MRI_Montpellier10 Jul 2024
Thrilled to announce the symposium organized by MRI on December 6th at Genopolys. Exciting talks about new imaging technologies and data analysis available on your MRI facility. Detailed program coming soon. Save the date !
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InstituteHumGenetics retweeted
CNRS Biologie@CNRSbiologie4 Jul 2024
#ResultatScientifique 🔎 | Organisation des chromosomes en méiose 🤝 @CNRS @CNRS_OccitaniE @umontpellier @IGH_MTP ✍️ Corinne Grey 📕 @MolecularCell | buff.ly/3VREK1d buff.ly/45RZPNZ
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InstituteHumGenetics retweeted
Shalaka Patil@ShalakaPatil115 Jul 2024
Heartiest congratulations to Marcel MECHALI for getting elected as a member of The Academy of Europe. Very well deserved for you contributions in the field of DNA replication and replication origins! Proud student! @CNRS @IGH_MTP @CNRS_OccitaniE @genopolys ae-info.org/ae/Member/M%C3%A…
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InstituteHumGenetics retweeted
Emile AlGhoul@EmileElGhoul19 Jun 2024
Immense honneur de recevoir aujourd'hui à l’ @InstitutFrance, le prix des "Grandes Avancées Francaises en Biologie 2024" de l' @AcadSciences 🎖🇫🇷 Travail de recherche et compétences scientifiques reconnu par les grands...
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InstituteHumGenetics retweeted
Steffen Fuchs@Steffen_E_Fuchs16 Mar 2024
After a successful 1st #YS2C, we're happy to announce the 𝟐𝐧𝐝 𝐘𝐨𝐮𝐧𝐠 𝐒𝐜𝐢𝐞𝐧𝐭𝐢𝐬𝐭 𝐂𝐚𝐧𝐜𝐞𝐫 𝐂𝐨𝐧𝐠𝐫𝐞𝐬𝐬, October 10+11 '24, at sunny #Montpellier. Present your research next to a fantastic line-up of international keynote speakers. tinyurl.com/YS2C2
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