@ISD_Research

ISD @ Institute for Stroke and Dementia Research (ISD), Ludwig-Maximilians-University (LMU) Director Martin Dichgans Imprint/Privacy Policy on https://xitter.cf/t.co/9UQP7vp5CA

 Munich, Bavaria
isd-research.de/
Joined September 2017
  • Tweets291
  • Following239
  • Followers957
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Incredibly happy and proud to share our newest work in @ScienceTM showing that Aβ promotes neuronal hyperconnectivity, thereby driving tau spread across connected brain regions. Many thanks to to first authors @SebRoemer and Fabian Wagner! science.org/doi/10.1126/scit… Thread below

Amyloid-associated hyperconnectivity drives tau spread across connected brain regions in Alzheime...

Aβ induces neuronal hyperconnectivity, which promotes tau spreading from temporal lobe epicenters to connected brain regions in Alzheimer’s disease.

science.org
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Martin Dichgans among „Highly Cited Researchers 2024” clarivate.com/highly-cited-r… 🙌
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The ISD co-organized the 9th International Conference on Cerebral Amyloid Angiopathy located at the Kardinal Wendel Haus next to English Garden/Munich. Experts presented latest developments in CAA research ranging from basics in research to studies in humans...
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ERC Starting Grant 2024 for Anna-Sophia Wahl and her team for studying fundamental principles of neuronal repair after stroke. isd-research.de/isd-research…
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ISD Research retweeted
Arthur Liesz@ArthurLiesz7 Aug 2024
Did you ever wonder why the risk for subsequent vascular events is increased after a first stroke or MI? Our answer, out now in @Nature nature.com/articles/s41586-0… A story about NETosis, DNA-sensing and inflammasome activation. Spearheaded by @StefanRoth86 and Jiayu Cao.
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Finally out today! Very proud of this story: Innate immune memory after Stroke drives remote organ pathology This study was led by superstar-postdoc @SimatsAlba and X-less Sijia Zhang. @CellCellPress cell.com/cell/fulltext/S0092…
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Authors from @ISD_Research, @unidue_zmb and colaborators develop repair approaches to reverse the effects of pathogenic mutations in protease HTRA1. nature.com/articles/s41467-0…
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Excited to share our newest work showing that neuroinflammation parallels tau spread in 4R tauopathies, suggesting a key role of microglia in tau progression. Many thanks to @M_Malpetti, @RoemerSeb, @johanneslevin, @GunterHoglinger and @matbrendel doi.org/10.1002/mds.29924
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October 15-17 9th ICAA in Munich, ISD co-organizing 9th Interational Conference on Cerebral Amyloid Angiopathy in Munich. Experts will present latest developments in CAA research ranging from basic research to studies in humans. Sign up now: icaaconference.org/registrat…
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ISD teams gathered for annual scientific retreat to present their projects and discuss work. There were presentations from Ph.D. students, a poster session, invited speaker talks, and an amazing three minute thesis competition. @PaquetLab @JekyllSarah @mgeorgakis1
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The 30th ISGC Workshop is in full swing! Thank you to everyone contributing to talks, posters and vivid discussions 🧠🩸🧬🔬 And a big thank you to our host @rainermpg and the @ISD_Research 🎉✨️🎊
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What honor to host the ISGC workshop, here at the preciousLMU St.-Vinzenz-Haus Munich City Great Keynote Lectures and Scientific Sessions and social activities #strokegenetics strokegenetics.org/
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Very excited to share that our DELiVR method is now open access published @NatureMethods. We created a simple, brain-wide cell analysis deep learning tool, no coding needed! Fiji Plugin makes it accessible to all. nature.com/articles/s41592-0… by @Dorie00 @Rami96614090 @moritz_negwer
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Age-related decline in brain endothelial cell (BEC) function contributes critically to neurological disease.(…) A study by isd investigators 👉@katalin_volgyi @Judit_GonzalezG et al. just published on @NatureAging read more here isd-research.de/isd-research
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ISD Research retweeted
Circulation@CircAHA10 Jan 2024
#OriginalResearch: Proteogenomic data integration reveals CXCL10 as a potentially downstream causal mediator for IL-6 signaling on atherosclerosis #AHAJournals ahajrnls.org/47une7c
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ISD Research retweeted
Nico Franzmeier@nfranzme3 Jan 2024
Super happy to share our new work out in @NatureComms, showing that synaptic changes accelerate amyloid-related tau accumulation and spread in #Alzheimer's disease. Many thanks to @_michael_scholl and many others! @ISD_Research, @goteborgsuni doi.org/10.1038/s41467-023-4…
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First results from 2,500 individuals from eMERGE, a study developed to test genomic risk assessment at a population level. Important PRS data for 10 diseases on: 👉performance 👉feasibility 👉medical actionability 👉translatability nature.com/articles/s41591-0…
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Continued dysfunction of capillary pericytes promotes no-reflow after experimental stroke in vivo academic.oup.com/brain/artic…
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A useful resource on the national prevalence of carotid atherosclerosis in China (>10M individuals) @JAMANetworkOpen 👉 increased cIMT (>1mm): 26% | 93% (!) for >80y 👉 plaque: 21% | 87% (!) for >80y 👉 stenosis: 0.6% | 4% for >80y jamanetwork.com/journals/jam…
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We are happy to present the new BRENDA Leducq Website with all information about the project, talks, meetings, and other news #brenda @FondationLeducq brenda-leducq.de/brenda
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