@IkonenLab

The Ikonen group is interested in the cell biology of cholesterol and related lipids and has developed tools to visualize their distribution and traffic.

 Helsinki, Finland
helsinki.fi/en/researchgroups/lipid-trafficking-lab
Joined January 2019
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🎉Thrilled to share our most recent work on how the lipid environment finely regulates the Golgi V-ATPase. A big THANK YOU to everyone in the Ikonen lab @IkonenLab @MiesvdStoel @rollingmeow, and our collaborators. 🔬Read more: biorxiv.org/content/10.1101/…

Control of Golgi- V-ATPase through Sac1-dependent co-regulation of PI(4)P and cholesterol

Sac1 is a conserved phosphoinositide phosphatase, whose loss-of-function compromises cell and organism viability. Here, we employed acute auxin-inducible Sac1 degradation to identify its immediate...

biorxiv.org
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New paper from our lab on how boosting homozygous knock-in efficiency enables robust generation of human auxin-inducible degron cells, by @ShiqianLi1 et al. in @GenomeBiology 🥳
Shiqian Li@ShiqianLi126 Feb 2024
Excited to share that my last paper at Ikonen Lab @IkonenLab was finally published at Genome Biology. It is interesting journey and thank to the great supports from friends, collaborators and my supervisor Elina Ikonen. @MiesvdStoel @rollingmeow @RaivioTaneli @_YZlab @OlkkonenVesa link.springer.com/article/10…
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