
Exclusive news, features, and analysis on the research, tools, regulations, and applications driving precision medicine. From the publisher of @GENBio
New Rochelle, NY
Joined April 2014
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🎧 Behind the Breakthroughs
Step into the minds shaping the future of medicine.
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#PrecisionMedicine #BehindTheBreakthroughs #MedTech #Biotech
Blood Test Identifies Residual Cancer
Microscopic traces of cancer in the bloodstream can identify patients who are high risk of their cancer returning, research suggests
@nyulangone
#biomarkers #hematologictests #NSCLC #lungcancer #ctDNA
hubs.li/Q04C0-890
With In Vivo 'Gene Writers,' Tessera Shows DNA Engineering Differentiation
The all-RNA #genomeengineering platform can permanently insert therapeutic genes and generate functional #CARTcells in vivo, addressing “copycat” criticism
@TesseraTx
#geneediting
hubs.li/Q04C0Bk70
Hussam Al Kateb: Inside Mayo Clinic’s Molecular Diagnostic Revolution
The Clinical Genomics Lab co-director discusses whole transcriptomics-based gene fusion diagnostics and evolving #cancergenomics innovation
@mayocliniclabs
#moleculardiagnostics
hubs.li/Q04BTRRz0
Targeted Brain Ultrasound Could Help Relieve Schizophrenia Symptoms
Low-intensity targeted #ultrasound could be an effective treatment for delusions in people with #schizophrenia or schizoaffective disorder
@ShohamLab @nyugrossman
#Alzheimersdisease
hubs.li/Q04BTPdT0
New Molecular Target for Treating Type 2 Diabetes Identified
Targeting the mitochondrial protein Miro1 could offer a new approach to treating insulin resistance in type 2 diabetes
@LSU @NIH @BrownUniversity
#diabetes #insulinresistance #mitochondria
hubs.li/Q04BTL6K0
IMU Biosciences and UK Biobank to Create Large Immune Dataset
The U.K. biotech IMU Biosciences will help create a large and detailed immune dataset for 80,000 people in the @uk_biobank
@WatersCorp @UltimaGenomics
#biobanks #immunecells #omics
hubs.li/Q04BLGK30
Early Drivers of Autoimmune Kidney Damage Identified, Opening Door to Targeted Treatment
New research reveals how autoimmune kidney inflammation develops and identifies an antibody-based strategy that may prevent lasting damage
@UOsaka_en
#genetics #omics
hubs.li/Q04BLF420
GLP-1 Drugs Linked to Fewer Heart Complications and Infections After Surgery
GLP-1 medications may reduce complications after surgery, with new research linking their use to fewer cardiovascular events and infections
@UTHealthHouston
#diabetes #GLP1
hubs.li/Q04BxXXY0
Breast Cancer Treatment Response Predictors Revealed Through Multi-Omics Analysis
Researchers use #multiomics and spatial profiling to identify potential #biomarkers of treatment response and resistance in breast cancer
@FudanUniversity
#breastcancer
hubs.li/Q04BxWdx0
Magnetic Millirobots Could Deliver Cancer Drugs Directly to Hard-to-Reach Tumors
A modular robotic system uses magnetic guidance to deliver drugs precisely, with potential applications in oncology
@JohnsHopkins
#anticancerdrugs #AI #drugdelivery
hubs.li/Q04BcbgM0
Single-Cell Profiling Exposes Hidden Diversity Within Pancreatic Tumors
Clonal diversity in #pancreaticcancer cells reveals potential biomarkers and targets linked to aggressiveness and immune evasion
@DespinaKalf @nyugrossman
#transcriptomics #scRNAseq
hubs.li/Q04Bc8F40
Advanced Omics Reveal 'Poor Outcome' Marker for Neuroblastoma
A gene signature for those mesenchymal cells that make #neuroblastoma resistant to standard therapy has been revealed
@DrAnandPatel14 @mikedyerlab @StJudeResearch
#omics #genesignature
hubs.li/Q04Bc7DV0
Trapping ecDNA in Micronuclei Improves Cancer Patient Survival
Trapping extrachromosomal (ec)DNA in micronuclei during cell division weakens aggressive cancers with high levels of ecDNA in their cells
@anton_gh @ChariteBerlin
#DNAdamage #cancertherapy
hubs.li/Q04Bc66W0
Whole-Genome Diagnostics Evolve with RNA and Pangenome Integration
@AmbryGenetics' GenomeNext test uncovers rare diseases with more comprehensive sequencing, diverse genomic references, and ongoing reanalysis
#genetictesting #WGS #DNA #rarediseases
hubs.li/Q04BpK790
ADPKD Gene Therapy Development at Newly Launched Estuary Biotherapeutics
As one of the world’s most common genetic diseases, developing treatments for ADPKD is both a daunting and important task
#EstuaryBiotherapeutics
#genetherapy #kidneydiseases #ADPKD
hubs.li/Q04BpJZW0
Metabolomic Aging Clock Predicts Chronic Disease, Mortality Risk
Researchers identify 56 age-associated metabolites to develop aging clocks linked to long-term health outcomes
@sjtu1896
#metabolomics #agerelateddiseases #aging #chronicdisease
hubs.li/Q04BgqZ30
CRISPR-Based Test Improves Detection of HIV and Other RNA Viruses
An engineered CRISPR Cas13a enzyme can detect RNA with 100 times greater sensitivity than its original version
@RiceUniversity
#CRISPR #HIV #diagnostictools
hubs.li/Q04Bgn-c0
Childhood Cancer Linked with Abnormal Antibodies
Children who develop cancer have an unusually high number of #autoantibodies that affect cellular machinery involved in DNA repair
@UiB
#antibodyresponse #pediatriconcology #DNArepair
hubs.li/Q04B8nv_0
Mechanical Pressure Triggers Cancer Cell Death, Revealing Potential New Defense Against Metastasis
Mechanical confinement does more than challenge migrating #cancercells. It may help determine which cells survive
@CAS__Science
#apoptosis #metastasis
hubs.li/Q04B7__g0
Lung and Mouth Bacteria Linked to Long COVID Severity and Symptoms
“What we don’t know is whether these changes came before a COVID infection...” said @ProfJDChalmers, chair of respiratory research at the University of Dundee.
hubs.li/Q04zZsf60
