Jesús Loarce (@JesusLoarce) header
Jesús Loarce (@JesusLoarce) profile picture

Jesús Loarce

@JesusLoarce

Rheumatology, Ramón y Cajal University Hospital. Interested in idiopathic inflammatory myopathy and interstitial lung diseases associated to CTD.

Joined March 2019
  • Tweets1.3K
  • Following281
  • Followers872
Aunque tuviese otros planes, este jueves 16, yo no me perdería esta jornada. Ideal para reumatólogos e inmunólogos. Os esperamos en el Ramón y Cajal. X Jornada de enfermedades autoinmunes sistémicas.
Image from Carlos Guillén (@Carlosguillenas)
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🔔 Recuerda que todavía te puedes apuntar al #webinar de @JOVREUM junto a la @SPReumatologia. 🗓️ Fecha: 14 de abril 🕜 Hora: 18:00 CET (17:00 hora de Portugal) ➡️us06web.zoom.us/webinar/regi…
Image from Soc.Esp.Reumatología (@SEReumatologia)
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Os invitamos a nuestra jornada de puertas abiertas para futuros residentes de Reumatología 👨‍⚕️🧑‍⚕️ el lunes 23 de marzo en el Hospital Ramón y Cajal 🏥 ¡Os esperamos! #MIR2026
Image from Reumatología Ramón y Cajal (@ReumatologiaRyC)
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1) Scleroderma lung study III (SLS-III), Phase II RCT ▶️ Mycophenolate (MMF) vs MMF + pirfenidone ▶️ 51 patients randomized (34% of intended recruitment, ⚠️underpowered) ▶️ No significant differences in FVC% at 18 months ▶️ Overall improvement in both groups (MMF effect)
Image from Jesús Loarce (@JesusLoarce)
Image from Jesús Loarce (@JesusLoarce)
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▶️ Differences in PROMIS-29 favouring MMF + pirfenidone ▶️ Trends towards improvement in quantitative HRCT metrics (non-significant) ▶️ More AEs with pirfenidone + MMF: GI disorders (55.6% vs 20.8%), photosensitivity (11.1% vs 0%) #SystemicSclerosis #ILD pubmed.ncbi.nlm.nih.gov/4129…
Combining Pirfenidone With Mycophenolate Mofetil for Systemic Sclerosis-Related Interstitial Lung...

Combining Pirfenidone With Mycophenolate Mofetil for Systemic Sclerosis-Related Interstitial Lung...

In this underpowered study, there was no statistically significant treatment difference in overall change in FVC-% between groups. MMF+PFD was not as well tolerated as MMF+PLA.

pubmed.ncbi.nlm.nih.gov
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Jesús Loarce retweeted
Cristina Macía (@reumacia) profile picture
Cristina Macía@reumacia29 Oct 2025
Tercer día de resúmenes #ACReview25 de @SEReumatologia que tengo el gusto de coordinar ¡Equipazo de revisores TOP! 🔝 Link 👉🏻 acr-review.ser.es
Image from Cristina Macía (@reumacia)
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Roxana González (@RoxOsler) profile picture
Roxana González@RoxOsler29 Oct 2025
Feliz y agradecida por haber compartido este #ACReview25 con un equipazo y una coordinación impecable. Un lujo trabajar con vosotros 💙@a_lois_ @montesa_maria @JesusLoarce @LuisCorTar @reumacia @SEReumatologia #ACR25
Image from Roxana González (@RoxOsler)
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Cristina Macía (@reumacia) profile picture
Cristina Macía@reumacia28 Oct 2025
Segundo día de resúmenes #ACReview25 de @SEReumatologia que tengo el gusto de coordinar ¡Equipazo de revisores TOP! 🔝 Link 👉🏻 acr-review.ser.es
Image from Cristina Macía (@reumacia)
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David Liew (@drdavidliew) profile picture
David Liew@drdavidliew27 Oct 2025
Screening for ILD in RA patients: CXR and PFTs by themselves are close to a waste of time. When it comes to screening (high-risk) RA patients, it’s HRCT (or lung USS) or nothing really. (in keeping with EULAR, ACR guidelines) #ACR25 ABST1335 @RheumNow
Image from David Liew (@drdavidliew)
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Cristina Macía (@reumacia) profile picture
Cristina Macía@reumacia27 Oct 2025
Primer día de resúmenes #ACReview25 de @SEReumatologia que tengo el gusto de coordinar ¡Equipazo de revisores TOP! 🔝 Link 👉🏻 acr-review.ser.es
Image from Cristina Macía (@reumacia)
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Cristina Macía (@reumacia) profile picture
Cristina Macía@reumacia12 Oct 2025
Espero veros a todos siguiendo el #ACR25 review 🇺🇸 de @SEReumatologia que tengo el gusto de coordinar Revisores TOP 🔝 - @RoxOsler ➡️ AR - @montesa_maria ➡️ EspA - @a_lois_ ➡️ LES, Sjögren, esclerodermia - @JesusLoarce ➡️ vasculitis, miopatías - @LuisCorTar ➡️ miscelánea
Image from Cristina Macía (@reumacia)
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Systematic review/meta-analysis ➡️treatments for rheumatoid arthritis interstitial lung disease 💊 Methotrexate ⬇️ mortality, FVC and composite progression 💊 Abatacept⬇️ HRCT and composite progression 💊 RTX/MMF/JAKi stabilize FVC #rheumatology #RAILD sciencedirect.com/science/ar…
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Update of the ATS/ERS Multidisciplinary Classification of the Interstitial Pneumonias🫁 ▶️Histological and radiological patterns (idiopathic, secondary) ▶️Interstitial vs alveolar ▶️New pattern (BIP), reclassification of old patterns (DIP➡️AMP, AIP➡️DAD) publications.ersnet.org/cont…
Image from Jesús Loarce (@JesusLoarce)
Image from Jesús Loarce (@JesusLoarce)
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Two recent articles ➡️ lung trasplant results in patients with connective tissue disease associated interstitial lung disease #ILD: ▶️Observational study, Johns Hopkins Hospital cohort, focused in #myositis pubmed.ncbi.nlm.nih.gov/4080… ▶️Systematic review pubmed.ncbi.nlm.nih.gov/4042…
Lung transplantation for connective tissue disease-related interstitial lung disease: Clinical...

Lung transplantation for connective tissue disease-related interstitial lung disease: Clinical...

Lung transplant recipients with CTD-ILD and IPF had similar rates of allograft failure, all-cause mortality, in-hospital complications, and acute rejection. However, these outcomes varied by CTD...

pubmed.ncbi.nlm.nih.gov
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Dr. John Cush (@RheumNow) profile picture
Dr. John Cush
@RheumNow11 Aug 2025
Novartis announced top line results of its ianalumab (VAY736;B cell inhibitor) in primary Sjögren’s dz. 2 RCTs, NEPTUNUS-1 and NEPTUNUS-2, met met primary endpoints w/ statistically significant improvements in disease activity in Sjögren’s patients. buff.ly/c6COFPw
Image from Dr. John Cush (@RheumNow)
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Subanalysis of the proDerm study: ▶️Predictors of response to IVIG: ⬆️cutaneous activity and anti-TIF1-γ➕ pubmed.ncbi.nlm.nih.gov/3991… ▶️Efficacy of IVIG on systemic manifestations: 🔝Skeletal, also in pulmonary, gastrointestinal and constitutional domains pubmed.ncbi.nlm.nih.gov/4061…
Predictors of response to intravenous immunoglobulin in patients with dermatomyositis: the ProDERM...

Predictors of response to intravenous immunoglobulin in patients with dermatomyositis: the ProDERM...

ClinicalTrials.gov, http://clinicaltrials.gov, NCT02728752.

pubmed.ncbi.nlm.nih.gov
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Two recent studies on rheumatoid arthritis associated interstitial lung disease (RA-ILD): ▶️ Review of lung ultrasound as a screening tool in RA-ILD pubmed.ncbi.nlm.nih.gov/4064… ▶️ Peripheral biomarker signatures in RA-ILD: analysis of the VARA registry pubmed.ncbi.nlm.nih.gov/4003…
Lung ultrasound as a screening tool for interstitial lung disease in patients with rheumatoid...

Lung ultrasound as a screening tool for interstitial lung disease in patients with rheumatoid...

LUS has shown a good performance in ILD detection. Further research and standardization efforts are needed to fully integrate LUS into routine RA screening protocols.

pubmed.ncbi.nlm.nih.gov
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🎥¡Seguimos difundiendo el conocimiento! Ya puedes ver la ponencia: “¿Qué hago con mis úlceras y calcinosis?”, a cargo de la Sra. Patricia García, enfermera de @ReumatologiaRyC del Hospital Ramón y Cajal. 👉youtube.com/watch?v=8PNI0dUO… #aeecongreso2025 #Esclerodermia #Reumatología
Image from A. E. Esclerodermia (@AEEsclerodermia)
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Cristina Macía (@reumacia) profile picture
Cristina Macía@reumacia8 Jul 2025
Primera revisión sistemática de la literatura 📚 de @FragoulisGeorge et al. sobre la combinación de FAMEb en enfermedades inmunomediadas (¡1200 pacientes!). Combinaciones más frecuentes: TNFi+IL/23i, JAKi+bDMARDs, y vedolizumab+TNFi. Acceso abierto 🔑 sciencedirect.com/science/ar…
Image from Cristina Macía (@reumacia)
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Nuestra enfermera Patricia García, habla del abordaje en la cura de las úlceras en pacientes con esclerosis sistémica. Fundamental el papel de la enfermera especializada en el cuidado de los pacientes.
A. E. Esclerodermia (@AEEsclerodermia) profile pictureA. E. Esclerodermia@AEEsclerodermia7 Jul 2025
#AEECONGRESO2025: PARTE 2 : Patricia García, enfermera de reumatología @ReumatologiaRyC y Dra.@MaykaFreire, del CHU Santiago de Compostela. Resumen completo de nuestro II Congreso Nacional de #esclerodermia para pacientes en:👇youtube.com/watch?v=vsX6Q8PA…
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