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Jupiter
Joined October 2009
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Joe Springer retweeted
Humans are extraordinarily sensitive to the smell of rain, known as petrichor, primarily due to the compound geosmin.
We can detect geosmin at parts-per-trillion levels, whereas sharks typically detect blood in water at parts-per-million or parts-per-billion concentrations.
This means humans are roughly 200,000 times more sensitive to the scent of rain than sharks are to blood.
Such heightened sensitivity likely evolved because smelling rain helped early humans locate fresh water and fertile environments.
What seems like a pleasant aroma today was once a crucial survival signal.
ALT Humans are extraordinarily sensitive to the smell of rain, known as petrichor, primarily due to the compound geosmin. We can detect geosmin at parts-per-trillion levels, whereas sharks typically detect blood in water at parts-per-million or parts-per-billion concentrations. This means humans are roughly 200,000 times more sensitive to the scent of rain than sharks are to blood. Such heightened sensitivity likely evolved because smelling rain helped early humans locate fresh water and fertile environments. What seems like a pleasant aroma today was once a crucial survival signal.
Joe Springer retweeted
The Arc gene (Activity-regulated cytoskeleton-associated protein) and memory engram cell are both central to the neuroscience of learning and memory, and they are functionally linked.
Arc isn’t just a plasticity gene—it forms virus-like capsids that transfer mRNA between engram cells, helps tag active synapses, and enables memory updating. Precise Arc levels are essential: too much or too little disrupts memory. Dysregulation is linked to Alzheimer’s, but targeted rescue shows promise. (Ashley, 2023; Chen, 2024; Kim, 2024)
Joe Springer retweeted
Little swimming pig and the tiny dive
nitter.gq/visualfeastwang/status…
Joe Springer retweeted
What happens to a #neuron exposed to beta-amyloid, the villain of #Alzheimers disease?🤯😳
Observe how the dendrites' movement and forming of synapses were inhibited by beta-amyloid. We also see an instability in the cells’ general shape
Source: Timelapse Vision
#mondaythoughts
Joe Springer retweeted
Ppl ( the magistrate judge might have missed) should read the recent case “ Medical Property Trust against Viceroy Research” in defamation.
cases.justia.com/federal/dis…
Joe Springer retweeted
Sugar gliders in flight
nitter.gq/froggyups/status/17437…
Joe Springer retweeted
It looks like a dead fish, until you realize those are grizzly bears. The scale of a whale, washed ahore in Larson Bay near Kodiak, Alaska on June 13, 2015
[full story: buff.ly/2sUNw5n]
Joe Springer retweeted
Do viral pathogens increase the risk of neurodegenerative disease?
Recent analysis of more than 400.000
patients across different biobanks point to several straightforward conclusions:
- Increased risk of developing neurodegenerative diseases persists up to 15 years after a single initial virus infection;
- The largest effect association was found between viral encephalitis exposure (caused by many viruses, including coronaviruses) and Alzheimer’s disease.
- Influenza with pneumonia was significantly associated with five of the six neurodegenerative diseases studied.
- The previously reported association between Epstein–Barr virus (EBV) infection and Multiple Sclerosis was also confirmed.
What about vaccines and the risk for neurodegenerative diseases?
(Anti-Vaxxers will love this part)
- Influenza and pneumonia vaccination has been found to reduce the risk for Alzheimer's and Parkinson's disease.
- Shingles (varicella-zoster) vaccination is associated with a reduced risk of dementia in both the United States and Wales.
- Protection against bacterial and viral infection benefits the brain since these infections may activate dormant herpes simplex type 1 (HSV-1) and herpes zoster virus (HZV). HSV-1 and HZV can interact to trigger AD.
Despite these findings, influenza vaccination
coverage in the United States is typically less than 50%, and only about 35% of people over the age of 60 have received a shingles vaccine.
In addition to vaccination, some studies suggest that using antivirals may reduce the risk of dementia. Antiviral target-specific drugs could also provide ways of ameliorating risk or halting neurodegeneration progression, but this remains a goal for future drug development.
References:
Viral pathogens increase risk of neurodegenerative disease nature.com/articles/s41582-0…
Vaccination Reduces Risk of Alzheimer’s Disease, Parkinson’s Disease, and Other Neurodegenerative Disorders ncbi.nlm.nih.gov/pmc/article…
Joe Springer retweeted
Nigerian Christians getting slaughtered and you don’t see the Squad caring about human rights or black lives mattering. The entire discourse is fake. It’s embarrassing to believe anyone is operating under anything close to universally applicable moral principles.
Joe Springer retweeted
What a surprise that, on the Friday before New Years, Prosecutors dropped the case against SBF that would have disclosed all who received his campaign contributions… 🤔🤔🤔
Ok - maybe it’s not so surprising…
nypost.com/2023/12/29/busine…
