@JonathanHo23

Resident | Department of Neurosurgery | Johns Hopkins Hospital UPSOM Class of 2025 (PSTP | RNEL)

noto.li/OZwU6H
Joined April 2021
  • Tweets20
  • Following148
  • Followers61
Epilepsy study presents a multimodal approach integrating intraoperative thalamic and sub-scalp electroencephalogram recordings with post-implant reconstructions to define neural targets affected by centromedian nucleus stimulation. nature.com/articles/s41467-0…
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Congratulations to our new PGY-1 class. We’re excited to have you join our family! Jonathan Ho, Sumil Nair, Pranav Warman, Carly Weber-Levine & David Zarrin @dazarrin #Match2025 #MatchDay2025 @hopkinsmedicine
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Brain injury patients gain arm, hand strength with deep brain stimulation, Pitt study finds. post-gazette.com/news/health… @ElviraPirondini @MCapogrosso
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Jonathan Ho retweeted
Pitt Med PSTP@pitt_pstp7 Oct 2024
Congratulations to MS4 @JonathanHo23 on his publication in @NatureComms!! Jonathan studied the use of deep brain stimulation on the motor thalamus for upper-limb motor recovery after cerebral lesions. @ElviraPirondini @RNELabs @PittTweet @PittNeurosurg nature.com/articles/s41467-0…

Potentiation of cortico-spinal output via targeted electrical stimulation of the motor thalamus

Nature Communications - Cerebral lesions result in loss of upper-limb motor functions. Here, the authors show that electrical stimulation of the motor thalamus can immediately and significantly...

nature.com
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Deep brain stimulation may provide immediate improvement in arm and hand strength and function weakened by traumatic brain injury, stroke and other neurodegenerative disorders. bit.ly/3Y3OA2C @MCapogrosso @ElviraPirondini @RNELabs @UPMC_PMR @UPMCPhysicianEd @JonathanHo23
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🚨New #preprints alert!🚨 Excited to share our work on #DeepBrainStimulation of the motor thalamus to enhance speech & swallowing. This continues our research led by @LillyTang & me, with guidance from @ElviraPirondini & Jorge Gonzalez-Martinez. 🧠1/8 medrxiv.org/content/10.1101/…

Targeted deep brain stimulation of the motor thalamus improves speech and swallowing motor functi...

Speech and swallowing are complex motor acts that depend upon the integrity of input neural signals from motor cortical areas to control muscles of the head and neck. Lesions damaging these neural...

medrxiv.org
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An fMRI study on anesthetized macaque monkeys examines how different depths of anesthesia uniquely affect brain networks temporal dynamics @ElviraPirondini @scottensel @dvdevill @JordyTasserie nature.com/articles/s42003-0…

Transient brain activity dynamics discriminate levels of consciousness during anesthesia

Communications Biology - An fMRI study on anesthetized macaque monkeys examines how different depths of anesthesia uniquely affect brain networks temporal dynamics, suggesting that brain dynamics...

nature.com
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Jonathan Ho retweeted
Jordyn Ting@_jting29 Apr 2024
Our team at @PittTweet is participating in the NSF’s Innovation-Corps training program this spring. If you or someone you know has expertise in/uses a DBS system, please reach out via email or QR-code below (lnkd.in/eM-YRjiM) to volunteer for a quick call with us!
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Although movement and imagery share population-wide brain responses in motor cortex, a subset of those exists in orthogonal and unique subspaces. @RNELabs @brian_dekleva @jenpgh @raeedcho @YuLikeNeuro @PittResearch nature.com/articles/s41562-0…
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Jonathan Ho retweeted
Genis@genisprat22 Feb 2024
Hello Twitter world🥳! This might sound crazy but today we share a paper showing that neurostimulation can revert motoneuron dysfunction produced by a neurodegenerative disease!🤯 @scottensel @dona_sere @DrRFriedlander @ElviraPirondini @MCapogrosso medrxiv.org/content/10.1101/…👇

Targeted Stimulation of the Sensory Afferents Improves Motoneuron Function in Humans with Spinal...

Spinal Muscular Atrophy (SMA) is an inherited neurodegenerative disease causing motoneuron dysfunction, muscle weakness and early mortality[1][1],[2][2]. Three therapies can slow disease progression...

medrxiv.org
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Somatosensory cortex and central amygdala regulate neuropathic pain-mediated peripheral immune response via vagal projections to the spleen nature.com/articles/s41593-0…

Somatosensory cortex and central amygdala regulate neuropathic pain-mediated peripheral immune...

Nature Neuroscience - The primary somatosensory cortex and central nucleus of the amygdala project to the spleen via the dorsal motor nucleus of the vagus nerve and regulate the T helper 2 (TH2)...

nature.com
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I really enjoyed working with @natnatkatic @SRaspopovic and @MCapogrosso and am very proud of our results! Restoring natural function through artificial inputs. Does electrical stimulation impact neural processing? We used intraspinal population analysis to answer this question👇
Natalija Katic Secerovic@natnatkatic21 Jan 2024
Finally, the results of many exciting and inspiring hours with @JMBalaguerSerra @SRaspopovic @MCapogrosso spent on analyzing the effects of peripheral nerve stimulation on neural processes in the spinal cord and brain, are out! cell.com/cell-reports/fullte…

Neural population dynamics reveals disruption of spinal circuits’ responses to proprioceptive input...

Katic Secerovic et al. examine the impact of electrical stimulation of cutaneous afferents on the processing of proprioceptive information in the monkey spinal cord. They find that proprioceptive...

cell.com
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Jonathan Ho retweeted
Scott Ensel@scottensel11 Oct 2023
Check out our new #preprint on discriminating levels of #consciousness during anesthesia! We demonstrate that temporal dynamics of functional networks can be a reliable and robust cortical signature of consciousness (1/2) biorxiv.org/content/10.1101/…

Transient brain activity dynamics discriminate levels of consciousness during anesthesia

The awake mammalian brain is functionally organized in terms of large-scale distributed networks that are constantly interacting. Loss of consciousness might disrupt this temporal organization...

biorxiv.org
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Super excited about our new #preprints on #DeepBrainStimulation of the motor thalamus to potentiate motor responses. Huge thank you to our team, especially my co-first author @JonathanHo23 and our mentors @ElviraPirondini and Jorge Gonzalez-Martinez. 1/10 medrxiv.org/content/10.1101/…

TARGETED DEEP BRAIN STIMULATION OF THE MOTOR THALAMUS FACILITATES VOLUNTARY MOTOR CONTROL AFTER...

Cerebral white matter tract lesions prevent cortico-spinal descending inputs from effectively activating spinal motoneurons, leading to untreatable muscle paralysis. However, in most cases the damage...

medrxiv.org
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Jonathan Ho retweeted
NPR
@NPR21 Feb 2023
Two stroke patients have regained control of a disabled arm and hand after researchers delivered electrical stimulation to their spines, paving the way toward a medical device that could aid movement. n.pr/3IgXhNP
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