We study stem cells- germline stem cells and intestinal stem cells- in different organisms to understand conserved mechanisms that regulate their behavior
San Francisco
Joined April 2020
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JonesLabUCSF retweeted
Excited to welcome new names to our speaker line up!
Our speakers will share cutting edge work on several mechanisms of aging, plus, the promise & challenges of translating them into interventions to improve human health during aging.
Keep updated & learn how to join us in Albania, May 2027➡️bit.ly/3SZZGpb #FusionAgingResearch
JonesLabUCSF retweeted
Fatty infiltration after muscle injury is a major clinical problem. BARI’s Brian Feeley & colleagues identify distinct human fibroadipogenic progenitor subpopulations and show that DLK1 helps restrain them from turning into fat. New therapeutic angle for muscle injuries!
JonesLabUCSF retweeted
We’re hiring! BARI is looking for a highly motivated Chief Strategist who loves aging biology and wants to lead community building across our research network. Help connect faculty, trainees, and ideas that advance the science of aging.
JonesLabUCSF retweeted
New ineNeuro, BARI’s Jeanne Paz shows that deleting c-Maf in somatostatin interneurons reduces their synaptic excitation and triggers spontaneous absence-like epileptiform activity. Important refinement of interneuron genetics in epilepsy. eneuro.org/content/13/7/ENEU…
JonesLabUCSF retweeted
Check out Dengke Ma in Science Advances: His team built a sensor (GENTIS) that tracks ionic stress in living animals and discovered that proton buildup in the gut drives sleep during molting in C. elegans. A striking link between cellular ion dynamics and behavioral quiescence.
JonesLabUCSF retweeted
Our conference chairs @JonesLabUCSF @OphirKlein are busy adding the final touches to the first draft of our #stemgastro programme! It's shaping up to be a fantastic meeting, don't delay in joining us in Mexico this November ➡️bit.ly/43wSRNZ
JonesLabUCSF retweeted
Congrats to BARI’s Roarke Kamber on being named a 2026 Pew-Stewart Scholar! His work exploring how macrophages team up (or battle) with cancer cells could open powerful new paths for treatments! geroscience.ucsf.edu/news/pi…
JonesLabUCSF retweeted
What an inspiring week at #JPM2026! It was energizing to connect with so many innovators pushing the frontiers of healthy aging. From all of us at BARI, thank you, stay safe on your journeys home, and see you soon!
JonesLabUCSF retweeted
How do Arctic ground squirrels thrive in extreme hypoxia? BARI member Dengke Ma and his team reveal in @emboreports conserved downregulation of triglycerides boosts resilience to low oxygen & aging, protecting mitochondria & extending lifespan. bit.ly/3NKhiCE
JonesLabUCSF retweeted
Congrats to BARI’s Tien Peng on this groundbreaking study in @CellStemCell! Identifying senolytic-sensitive fibroblasts that rewire lung cancer metabolism opens new doors for targeting aggressive tumors. A major step in cancer & aging research. Read more: bit.ly/3L7ATfr
JonesLabUCSF retweeted
Research from @ishahjain and colleagues published in @CellCellPress shows that HypoxyStat, can prevent or reverse #mitochondrial disease in a preclinical mouse model. bit.ly/4kh0csc
JonesLabUCSF retweeted
“It’s a paradigm shift to know that the silent X doesn’t stay asleep,” says Dena Dubal, a neuroscientist and neurologist at the University of California School of Medicine in San Francisco, who led the study.
go.nature.com/3Di2d6K
JonesLabUCSF retweeted
Have you seen the latest @Nature Index Ratings for Aging research in 2025? BARI’s innovations helped propel @UCSF to #2 globally! Incredibly grateful for our collaborators working with us to push boundaries against age-related decline. Full list here: bit.ly/4aInvZq
JonesLabUCSF retweeted
Exciting breakthrough in Parkinson’s research! BARI scientist Ken Nakamura and lab show in @ScienceAdvances how CHCHD2 mutation-induced mitochondrial dysfunction in DA neurons leads to α-synuclein aggregation in vivo. #Parkinsons #Neuroscience bit.ly/4aWt4n4
JonesLabUCSF retweeted
Congrats to BARI postdoc Jarin Tusnim (Piao Lab), on securing Cure Alzheimer’s Fund award! Jarin investigates how ADGRG1 enables microglia to protect against tau spreading, unlocking new ways to boost microglial resilience and target therapies for AD. Proud of our BARI talent!
JonesLabUCSF retweeted
JonesLabUCSF retweeted
Have you had a chance to check out BARI’s Xian Piao and her team’s paper in @NeuronJournal? They show how microglial ADGRG1 activates MYC to drive protective responses against Alzheimer’s – boosting phagocytosis & reducing amyloid. A major step forward in AD research! #Alzheimers
JonesLabUCSF retweeted
In case you missed it: BARI researcher John Greenland and team show frailty in lung transplant recipients links to shorter telomeres and anemia, but not epigenetic age or inflammation. Selective aging hallmarks at play! #Frailty #Transplant amjtransplant.org/action/sho…
JonesLabUCSF retweeted
1/ Can we find more precise and even safer ways to rejuvenate vision?
As a step towards this goal, I am excited to share this preprint of my 1st postdoc work from @JswLab with amazing collaborators, esp. @Bruce_Ksander! Using functional genomics, we discovered GSTA4 as a key OSK effector for oxidative resilience—overexpressing it alone rejuvenates RPE & restores vision.
A breakdown👇biorxiv.org/content/10.1101/…
