Senior Advisor @EliLillyandCo · ex @Pfizer · PhD @UCSanDiego @kjgaulton lab · Genetics and Genomics
Boston, MA
Joined August 2020
- Tweets12
- Following49
- Followers79
- Likes60
Josh Chiou retweeted
Out today: @kjgaulton and @msanderlab study of T1D risk mediated by beta cell survival in response to pro-inflammatory cytokines cell.com/cell-genomics/fullt…. Special congrats to first authors Han Zhu and Mei-Lin Okino!!
Josh Chiou retweeted
Our pre-print describing the @uk_biobank Pharma Proteomics Project (UKB-PPP) is now online!
biorxiv.org/content/10.1101/…
We identify 10k+ genetic associations w/ protein concentrations; 85% are new.
The data should help drive discovery of new biomarkers, diagnostics & medicines.
Josh Chiou retweeted
Single cell chromatin accessibility atlas of ~1.2M cCREs in 222 human cell types, invaluable resource for annotating complex disease variants. Congrats to Kai, @jamesdhocker, @CEpigenomics, @JoshChiou, Ren lab
- w/ support from @FNIH_Org #AMPT2D
cell.com/cell/fulltext/S0092…
Josh Chiou retweeted
Our latest work in @CellCellPress is a cell atlas of chromatin accessibility in 30 human tissues, integrated with prior data from 15 fetal tissues:
- 222 cell types, ~1.2 million cCREs
- Cell type & adult/fetal-specific elements
- Interpretation of GWAS
cell.com/cell/fulltext/S0092…
Josh Chiou retweeted
#pfizer has an active and robust post-doc program. Check out this opportunity in our Rare Disease Genetics group!
Please reach out to my colleague @joanneberghout for more information!
I know some of you are here for careers! Check this out and say hello if you're interested #ASHG21 Postdoctoral Fellow, Rare Disease Research Unit #genetics #rare #industry careers.ashg.org/jobs/156316…
Josh Chiou retweeted
Our paper out in @Nature - genetic association and single cell epigenomics reveal novel T1D signals and cell type-specific regulatory programs - which together implicate exocrine pancreas in T1D risk. Led by @JoshChiou and thanks to our great collaborators nature.com/articles/s41586-0…
Josh Chiou retweeted
🤩Out today @NatureGenet
Single-cell chromatin accessibility identifies pancreatic islet cell type– and state-specific regulatory programs of diabetes risk | go.nature.com/31Br2Ef
Josh Chiou retweeted
Out today! Insights into islet cell type- and state-specific gene regulatory programs from genetics, single cell-resolved islet chromatin maps, hESC-beta cell models. Monumental team effort together with @kjgaulton @CEpigenomics spearheaded by @JoshChiou
doi.org/10.1038/s41588-021-0…
Josh Chiou retweeted
Our study combining T1D GWAS in ~500k samples and discovery of many novel signals with cell type-specific chromatin maps of pancreas and blood - multiple T1D signals map in exocrine sites, incl. one w/ distal regulation of CFTR in ductal cells
biorxiv.org/content/10.1101/…
