Kade π§π»βπ¬π retweeted
Clinical case study by Malcolm Tran et al.
Diagnostic Challenges in Gamma Heavy Chain Disease: A Case of Overestimated Immunoglobulin G Concentration
buff.ly/NRFVIT8
Commentaries:
Rebecca Treger buff.ly/oUKWdtp
Kade Flowers buff.ly/GUtHESz
@KadeF96
Kade π§π»βπ¬π retweeted
I just don't understand the people that aren't completely obsessed with space... look at what my 12" telescope is looking at right now. INSANE.
I cannot eay this enough. A 'negative' tumour marker result NEVER excludes malignancy and a 'positive' never diagnoses malignancy in its self. And yes, this includes CA 125 and PSA. Tumour marker fishing is also a bad idea. Pre-test probability is extremely important.
Kade π§π»βπ¬π retweeted
For doctors, most diagnoses come from the history and examination. In many non-medical pathways, it can feel like the reverse: very little diagnosis from history/exam, and a heavy reliance on tests or onward referral, sometimes with no working diagnosis at all. If someone doesnβt understand what history and examination are for, itβs easy to skip them and default to βdo testsβ or βadmit/refer so a specialist can diagnoseβ.
The problem is that tests are then interpreted without a Bayesian βa prioriβ anchor. Without a pre-test probability built from a good story, a focused exam, and an understanding of how common conditions are so youβre left with results that can mislead, over-diagnose, or generate incidental findings. And if you donβt have a detailed grasp of disease patterns, you donβt know which questions to ask or what to look for to diagnose dementia or depression or diabetes or diphtheria. You canβt form a meaningful differential if you donβt know whatβs common, whatβs dangerous, and whatβs discriminating.
So the whole process drifts into secondary referrals and scanning as the default route to certainty. In parallel, some non-medical exams donβt require a deep knowledge base, so people are expected to βlook it upβ in real time under pressure. That isnβt the same as understanding, and itβs hard to expect consistently good outcomes from it.
The final issue is that often one doesn't know what one doesn't know. This can lead to overconfidence or a very defensive position.
Finally if you want to be seeing patients and making good diagnoses there is course for this called Medicine. Exams do expect knowledge.
Kade π§π»βπ¬π retweeted
If you think extremism only comes from one side, you are part of the problem
Kade π§π»βπ¬π retweeted
This dog already saw this week's news and decided her dad didn't need to know all that. 14/10 (Sasha via ViralHog)
Kade π§π»βπ¬π retweeted
This is Parker. He will not eat until he receives a forehead kiss. 13/10 would give him so many smooches
SPACE FACT #6: Magnetars - a type of neutron star - have a magnetic field a TRILLION times stronger than the field surrounding Earth. This is so powerful that if you found yourself 1,000 km away from one, you would die as the electrons in your body's atoms would be distorted π€―.
Kade π§π»βπ¬π retweeted
By far the most beautiful launch Iβve seen to date.
This is one of thousands of photos I captured across 7 cameras. I canβt wait to share more with you!
If we can't afford to pay good doctors and all other NHS staff the global market rate to keep them here to maintain a world class health service, then we cannot afford the NHS. It's as simple as that.
Kade π§π»βπ¬π retweeted
My wife cheated on me at a Linkin Park concert but in the end, it doesnβt even matter.
Absolutely delighted to have passed the module 1 and module 2 exams for part 2 of the Royal College of Pathologists. I never have to sit another exam again! Now to becoming a fellow and paying the RCPath Β£600 a year π
USS Callister: Into Infinity was an absolute masterpiece! I loved it even more than the first one! As sequels go, that was pretty amazing. #BlackMirror #USSCallister
This is very concerning. X isn't perfect, but one thing it is good for is allowing everybody to speak their mind and critique, which is essential for organisations as important as this. You can't just run away from criticism - listen and do better (your job) instead.
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Kade π§π»βπ¬π retweeted
A positive troponin is not an MI. A positive BNP is not heart failure. A positive lactate is not sepsis. Please for the good of society can this be properly taught in all medical training programs?
















