Computer scientist, computational biologist/chemist/physicist/cosmologist; PhD, MIT / Harvard Medical School; former Google AI research scientist; TED Fellow

Planet Earth
Joined May 2009
I created a Claude Code skill that scours every major indexing service on the web to find the source or PDF for scientific papers, so that when you cite a paper, the claims you make around the citation are grounded in the actual content of the cited paper: github.com/lukehutch/allpape…
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What do you say to your family when you don’t know if you’ll ever see them again? In February 2022, he told his wife and children the war had begun. Then he left as Russian forces advanced towards Kyiv, unsure what the coming hours would bring. This is President Volodymyr Zelenskyy. Before politics, he built a successful career in Ukrainian television as a writer, producer and performer, even portraying a president on screen. In 2019, he was elected President of Ukraine. Three years later, Russia launched its full-scale invasion. Sitting down with him was surreal and an enormous responsibility. It was a rare chance to hear his account of the first hours of the war and the decisions that followed. We discussed things like: How he found out Russia had invaded. Why he refused an offer to evacuate Kyiv. The 64km Russian military convoy advancing towards the capital. How Russian forces tried to capture a key airport. His account of discovering hundreds of bodies after Russian occupation. What he believes it will take to end the war. But I also wanted to understand how he’d been coping. One of my first questions was simply, “How are you doing?” His answer was: “It’s hard.” He spoke about meeting parents whose children had been killed. Some, he explained, simply ask him for a hug. And as he spoke, there were tears in his eyes. Whatever your views on the war or the decisions made by those involved, this is a rare opportunity to hear his account of events that have changed millions of lives. Because behind every map, every headline and every political decision, there are real people. Out now on all platforms ❤️👊🏾 (President Zelenskyy was recorded in Ukrainian and dubbed in English.)
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One of the worst spec decisions of all time was for IEEE 754 to treat 0.0 and -0.0 as different numbers.
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Luke Hutchison retweeted
Woooooowww. This is the confirmation we’ve been waiting for! Moderna and Merck’s personalized mRNA cancer vaccine reduced the risk of melanoma recurrence or death by 42% when added to Keytruda after surgery, compared with Keytruda alone! And yes, it uses the same mRNA technology behind the COVID vaccines!
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Two MIT mathematicians have proposed a significant change to the future of mathematical research. In an essay published on 21 October, Pavel Etingof and Slava Gerovitch argue that mathematicians should increasingly be evaluated for their understanding, judgment, and creativity rather than simply for being the first to prove a theorem. They suggest that future PhD theses need not necessarily contain the first proof of a result. Originality could instead come from new ideas, connections, explanations, or methods. They also propose greater emphasis on oral examinations, collaborative research, and AI-assisted mathematical exploration. Their central argument challenges a longstanding academic tradition: mathematical achievement should not be measured primarily by who proves something first.
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Argon getting a little over-excited
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If you love math, CS, and/or physics, seriously, do yourself a huge favor and go watch this video. This is the most sensible and inspiring thing I have heard so far on the positive future that AI is bringing to all of us. youtu.be/LKrwhjOI8Nc
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OK so people keep hating on Antigravity, but show me Claude Code or Codex trying to render complex LaTeX math as ASCII art... (Also Antigravity is still written by humans, whereas the others are vibed -- so this is ultra-impressive...)
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This is EXACTLY why this is the beginning, not the end, of math. Those who will make 100x the typical human impact in the future will be whose who continue to use 100% of their own cognitive effort and creativity, and use AI to amplify their own efforts.
For decades, a key question about the challenges of high-dimensional computation resisted proof. New research resolves the KLS conjecture, removing a major barrier to understanding the efficiency of randomized algorithms used throughout science and computing. msft.it/6011aar01
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Luke Hutchison retweeted
This woman has a message for her fellow Texans.
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I’m very opinionated. So it’s nearly impossible for me to hear someone’s arguments and *not* find something I disagree with. (This includes reading things I myself wrote years - or weeks - ago.) And yet the amazing Grant Sanderson @3blue1brown has put out a long, detailed video on the future of mathematics, in which I cannot find a single flaw. I’ll be sending this to every PhD student and postdoc I know, and strongly recommend everyone watch it. youtube.com/watch?v=LKrwhjOI… (Of course I tried to say many of the same things in my conversation with Thomas Koberda. But Grant’s version, unsurprisingly, does an infinitely better job at communicating those ideas!)
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Luke Hutchison retweeted
the best ones
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Luke Hutchison retweeted
Recently attended an in-person handheld game console hackathon. I wrote a raycaster by hand. Someone wearing a “I ❤️ slop” tshirt saw mine and said “oh I wrote a ray caster too!”. They showed me. It was a ray *tracer* and claude did all the work. The person didn’t know basic graphics terms. They couldn’t answer basic questions about how it worked, could only talk about their prompting harness. Sad how AI is ruining the craft and community for people that actually like to program and have spent their lives getting good at it.
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Luke Hutchison retweeted
"Some U.S. officials say that Musk acted unilaterally and that Trump didn’t specifically order any retribution against Ukraine. But a person familiar with the situation said Musk talked to multiple senior administration officials, including with Trump, before imposing the new speed cap, which Ukrainian officials said had allowed Russian missiles to evade their defenses." Once again, for emphasis: this is Elon Musk unilaterally violating a contract between his company and a paying customer in a mission-critical situation, where lives were at risk and were almost certainly lost as a direct result of his actions, for purely personal reasons that had nothing to do with SpaceX's commercial interests. It's as serious a breach of trust as can possibly be imagined. Who could possibly trust a contract with a Musk-controlled company now?
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Luke Hutchison retweeted
I launched the first image and video generation models at Google, and kept asking why all AI designs look the same. AI has brought us the WORST era of design. It made content creation effortless, but it also made 90% of it look painfully generic. My co-founder and I spent 2 years building in stealth to change that. Meet Vyb, the first AI design model that understands your taste like a designer would. RT + comment your website URL and we’ll make your first design.
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Utter insanity.. how
Portal jumping through gaussian splat worlds with WebGPU. real time. sound on.
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Luke Hutchison retweeted
Introducing Pixel - a library for building GUIs in the terminal - 120 FPS pixel-perfect graphics - Embeddable inside existing TUIs - Built in chromium webview component pixelgui.com
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Pro-tip: never announce vaporware
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Luke Hutchison retweeted
[Original in Polish. Text in the image translated and edited using AI]
🤖 Made with AI
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Luke Hutchison retweeted
the gamma equation in special relativity is objectively the worst way you can write what is clearly an application of the pythagorean theorem. was c/√c^2-v^2 so hard?
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