@LabNir

Studying sleep, anesthesia, neuromodulation, memory, and sensory processing, combining human and animal models, Tel Aviv University | @labnir.bsky.social

yuvalnirlab.com/
Joined February 2019
  • Tweets1.3K
  • Following655
  • Followers1.8K
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Yuval Nir 💔 retweeted
Massimo
@Rainmaker1973Sep 18
Arthur C. Clarke on BBC's Horizon in 1964, when he gave some astonishing predictions about the future.
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A sleeping octopus changing colors as she dreams.
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BryanRoth
@zenbrainestJun 4
Memory reactivation underlies experience-dependent adaptive regulation of sleep | Science Another win for chemogenetics science.org/doi/10.1126/scie…

Memory reactivation underlies experience-dependent adaptive regulation of sleep

Recent memories are consolidated during sleep by spontaneous reactivation. However, whether and how memory reactivation affects sleep dynamics remain unclear. By tracking and modulating memory...

science.org
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Ready to expand your neuroscience expertise? Join one of the world’s leading neuroscience communities. 🧠 150+ labs 🎓 Research thesis 💰 Tuition exemption + stipend 📅 Deadline: March 12, 2026 🔗information and registration- international.tau.ac.il/Neur… #Neuroscience #tau #Students
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Yuval Nir 💔 retweeted
CLaE
@leafs_sJan 30
Nature Cholinergic modulation of dopamine release drives effortful behaviour nature.com/articles/s41586-0…

Cholinergic modulation of dopamine release drives effortful behaviour

Nature - In the nucleus accumbens, acetylcholine boosts dopamine release to promote effortful behaviour.

nature.com
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Episodic memory consolidation by reactivation of human concept neurons during sleep reflects contents, not sequence of events biorxiv.org/content/10.64898… #biorxiv_neursci

Episodic memory consolidation by reactivation of human concept neurons during sleep reflects...

How do our brains manage to store our everyday experiences into memory? Neurons in the human temporal lobe that respond to the concept of an individual person or object have been shown to provide the...

biorxiv.org
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Yuval Nir 💔 retweeted
ESRS@ESRS_Sleep18 Sep 2025
Join Prof. Dr Marcello Massimini at #eSleepEurope2025 as he explores “Local sleep and the emergence of sleep-like activity in specific states such as brain damage.” ➡️ 9 October, 13:00–13:45 CEST 🔗 Register here: ow.ly/lN8X50WXtUs #eSleepEurope2025 #ESRS
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A new study shows that a small cluster of neurons called the locus coeruleus has a specialized pathway to the brainstem that controls sound-evoked awakening with the release of norepinephrine. @LabNir @NMatosevich scim.ag/4n7G8t9
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Anticipatory eye movements during repeated movie viewing reveal when and what is remembered. Gaze patterns correlate with explicit reports, offering a method to detect memory for events. @LabNir @FlavioSchmidig @YaminEtAl @omerxsharon @CharanRanganath nature.com/articles/s44271-0…

Anticipatory eye gaze as a marker of memory

Communications Psychology - Anticipatory eye movements during repeated movie viewing reveal when and what is remembered. Gaze patterns correlate with explicit reports, offering a method to detect...

nature.com
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Cortical closed-loop electrical stimulation can prevent pathological hippocampal-cortical communication and preserve long-term memory in focal epilepsy @dk2955 @AhnafRHassan @UCIEngineering @NeuroE_C @UCIrvine @UCI_EpiCenter nature.com/articles/s41593-0…

Closed-loop electrical stimulation prevents focal epilepsy progression and long-term memory...

Nature Neuroscience - Pathological neural communication drives the spread of the epileptic network and contributes to memory impairment in focal epilepsy. The authors show that closed-loop...

nature.com
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Our latest work, published in @CellCellPress, identifies a rare soluble #tau species in human #Alzheimer’s brain that suppresses CA1 complex-spike bursting, a hippocampal neuronal firing pattern that is critical for learning and memory. cell.com/cell/fulltext/S0092…

Alzheimer’s disease patient-derived high-molecular-weight tau impairs bursting in hippocampal...

In mouse models, tau impairs neuronal complex spike bursting and associated network processes in hippocampus CA1 alongside CaV2.3 downregulation. Soluble high-molecular-weight tau species drive these...

cell.com
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Yuval Nir 💔 retweeted
Dion Khodagholy@dk295530 Apr 2025
How to develop network-level interventions to address cognitive comorbidities of epilepsy? Here is our take! nature.com/articles/s41583-0…
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Yuval Nir 💔 retweeted
David Omer@DavidOmer_15 Apr 2025
Nachum's new book Natural Neuroscience is out! A fresh take on how brains work in the real world—well worth a read.
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Yuval Nir 💔 retweeted
David@dav1dcg13 Apr 2025
Very cool video! Every Eye In The Animal Kingdom youtube.com/watch?v=2vjmQooF…
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Deficient synaptic neurotransmission results in a persistent sleep-like cortical activity across vigilance states in mice: Current Biology cell.com/current-biology/ful…

Deficient synaptic neurotransmission results in a persistent sleep-like cortical activity across...

Using a mouse model of altered neurotransmission (Vamp2rlss), Guillaumin et al. show that differences typically observed between vigilance states in neural dynamics and spectral signatures can be...

cell.com
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Yuval Nir 💔 retweeted
Anita Luthi@anita_luthi17 Mar 2025
👉👉New paper alert from @LabLuthi ! Newly promoted Dr. Cherrad, with @GFoustoukos, @FernandezLmj and others combines stimulation of sensory neurons from the #vagus nerve with #sleep, #heartrate, temperature and #locuscoeruleus recordings @unil #FBM #Neuro
bioRxiv Neuroscience@biorxiv_neursci16 Mar 2025
Vagal afferent activation induces a NREM-sleep-like state with brain-body cooling, but locus coeruleus activation biorxiv.org/content/10.1101/… #biorxiv_neursci

Vagal afferent activation induces a NREM-sleep-like state with brain-body cooling, but locus...

Parasympathetic nervous system activity, vital for restorative sleep, is influenced by vagal sensory afferents, but how these shape brain-body correlates of sleep remains open. We investigated this...

biorxiv.org
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Visualizing Effective Connectivity in the Human Brain Preprint: biorxiv.org/content/10.1101/… Code: github.com/ComaRecoveryLab/S… YouTube video: youtu.be/V0hqs-noYNg Download video & figures: zenodo.org/records/14974861 Led by #XanderAtalay & #TeoFecchio @MGH_CNTR @MGHMartinos @MGHNeuroICU
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Yuval Nir 💔 retweeted
Tal Laviv@LavivTal21 Feb 2025
Very excited to share the first paper from my lab. We engineered a new PTEN sensor that permits dynamic imaging in living cells. We showed that this allows to visualize PTEN activity with subcellular resolution in the intact brain. Now published in Nature Methods
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Increased slow wave activity in response to sleep deprivation is highest immediately after micro-arousals | bioRxiv biorxiv.org/content/10.1101/…

Increased slow wave activity in response to sleep deprivation is highest immediately after micro-...

Non-rapid eye movement (NREM) sleep is not uniform but characterized by brief intrusions of wake-like brain activity, known as micro-arousals or brief awakenings. Although micro-arousals are an...

biorxiv.org
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Yuval Nir 💔 retweeted
Noa Matosevich@NMatosevich30 Jan 2025
Excited to share our new preprint out on biorxiv! We found a specific LC pathway that influences sensory evoked awakenings from NREM sleep. ⁦@LabNir⁩ biorxiv.org/content/10.1101/…

An early surge of norepinephrine along brainstem pathways drives sensory-evoked awakening

The locus coeruleus norepinephrine (LC-NE) system regulates arousal and awakening; however, it remains unclear whether the LC does this in a global or circuit specific manner. We hypothesized that...

biorxiv.org
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