We use the model insect Drosophila melanogaster to study totes dope hormonal regulation of growth & development, as well as models of neuropsychatric disorders.
Copenhagen, Denmark
Joined July 2019
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RewitzLab retweeted
Researchers have discovered a cell surface receptor that is essential for adipose #tissue responding properly to #insulin. When the receptor is inactivated, the response to insulin is insufficient. However, a researcher says that it may be possible to stimulate the receptor – thereby protecting against the #development of type 2 #diabetes.
#sciencenewsdk
sciencenews.dk/en/recently-d…
RewitzLab retweeted
Latest from the lab: What are the mechanism by which insects maintain systemic ion and water balance as they interact with their environment? Another great collaboration with @DenholmLab!annualreviews.org/eprint/FXM…
RewitzLab retweeted
Online now! Glycolysis-derived alanine from glia fuels neuronal mitochondria for memory in Drosophila dlvr.it/SyTZ2L
RewitzLab retweeted
Let's try this again - look's like twitter can't handle the video 😂. Really excited to share the lab's first Drosophila paper and it's a big one. Check out our preprint shorturl.at/gqrvO where we present the complete neural connectome of an animal circadian clock
RewitzLab retweeted
New paper: Petsakou, A., Liu, Y., Liu, Y. Comjean, A., Hu, Y. and Perrimon, N. Cholinergic neurons trigger epithelial Ca2+ currents to heal the gut. Nature (2023). doi.org/10.1038/s41586-023-0…
RewitzLab retweeted
Michael Ashburner (1942-2023).
Rubin GM. Curr Biol. 2023 Aug 18:S0960-9822(23)01072-2. doi: 10.1016/j.cub.2023.08.029.
RewitzLab retweeted
Our last review:
Drosophila TNF/TNFRs: At the crossroad between metabolism, immunity, and tissue homeostasis
J. Colombani & D.S. Andersen - FEBS Letters - Wiley Online Library febs.onlinelibrary.wiley.com…
RewitzLab retweeted
Curious about how some beetles have evolved to drink, not with their mouths, but with their rectum? Check out our latest Quick Guide in the current issue of @CurrentBiology. In collaboration with @RobinBeaven @DenholmLab sciencedirect.com/science/ar…
RewitzLab retweeted
If you are interested in how genes are regulated in response to dietary sugar, please check out our recent publication 'Sugar-responsive inhibition of Myc-dependent ribosome biogenesis by Clockwork orange': cell.com/cell-reports/fullte… 1/
RewitzLab retweeted
Fresh preprint! Collaborative work with Chris Wegener's lab looking at the release of clock neuropeptide pigment dispersing factor.
PDF neuropeptide signals independently of Bruchpilot-labelled active zones in daily remodelled terminals of Drosophila clock neurons biorxiv.org/cgi/content/shor… #bioRxiv
RewitzLab retweeted
How do animals weigh competing needs to maintain nutrient and fluid balance? Check out our recent review in #BioEssays in which we aim to provide a framework for understanding the polymodal optimization of homeostasis in insects. Also, pretty pictures... onlinelibrary.wiley.com/shar…
RewitzLab retweeted
Thanks @crisprflydesign!
Nice #CRISPR clones showing that the TNF Receptor wgn plays an important role in lipid metabolism in the #Drosophila intestine.
science.org/doi/10.1126/scia…
RewitzLab retweeted
New paper: split-intein Gal4 provides intersectional genetic labeling that is repressible by Gal80.
Ewen-Campen, Luan, Xu, Singh, Joshi, Thakkar, Berger, White, Perrimon. PNAS. 2023 doi: 10.1073/pnas.2304730120. Epub 2023 Jun 5. PMID: 37276389
RewitzLab retweeted
New paper: Gut AstA mediates sleep deprivation-induced energy wasting in Drosophila.
Li Y, Zhou X, Cheng C, Ding G, Zhao P, Tan K, Chen L, Perrimon N, Veenstra JA, Zhang L, Song W. Cell Discov. 9(1):49. doi: 10.1038/s41421-023-00541-3. PMID: 37221172
RewitzLab retweeted
Do flies dream of protein? How the gut regulates sleep depth dlvr.it/SnjNxl
RewitzLab retweeted
New paper: Chung, Ye., Park, Zuo, Z., Mok, Kanca, Tattikota, Lu, Perrimon, Lee, Bellen (2023) Very long-chain fatty acids induce glial-derived Sphingosine-1-Phosphate synthesis, secretion and neuroinflammation. Cell Metabolism. doi.org/10.1016/j.cmet.2023.…
RewitzLab retweeted
Scientists have long known that beetles can survive in extremely dry conditions — thanks to their unusual ability to suck water from the air through their rear ends. Now biologist Kenneth Veland Halberg can explain how and tells Nil Köksal why it matters. cbc.ca/radio/asithappens/bee…
RewitzLab retweeted
Interested in gut-brain signalling, enteroendocrine cells & sensory cell biology? Then join our fantastic speakers @lbeutler7 , @rituja14 , @VBLu_Lab , @ConiAlcaino , & @LabRewitz at the @NeuroforumNWG symposium no. 1️⃣ tomorrow.
nwg-goettingen.de/2023/uploa…
RewitzLab retweeted
Excited to share the first preprint of the lab! Great work of our first PhD student @ChristianFokdal investigating the role of activins in adapting gut size to food intake and promoting regenerative growth @BIO_UCPH @UCPH_Research
Drosophila activins adapt gut size to food intake and promote regenerative growth biorxiv.org/cgi/content/shor… #biorxiv_physio
RewitzLab retweeted
Out now in @CurrentBiology! Wonder how animals can tell that #WinterIsComing? Here we showed that a circadian neuropeptide is involved in sensing and transmitting seasonal information to trigger seasonal adaptations.@joanna_c_chiu @LatinaNeuroNerd & CAT ❤️
cell.com/current-biology/ful…
