We are a synthetic biology research group in the Bioengineering Department at Rice University.

Joined June 2018
In this new paper, we collaborated with the wonderful @veiseho group to encapsulate engineered bacteria in hydrogel spheres to enhance their survival through the GI tract and ability to diagnose intestinal inflammation. Congrats to the team! doi.org/10.1016/j.biomateria…
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Bacteria phosphorylate response regulator proteins to survive stresses, colonize hosts, and resist antibiotics among other processes. Here, we report an optical method to monitor this process in live cells. Congrats @Rice_BIOE Ph.D. Ryan Butcher. doi.org/10.1073/pnas.2201204…
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We are looking for summer undergraduate researchers to work on a new NSF-funded project to develop a synthetic biology/optogenetics teaching module for high school classrooms, starting ASAP. Please reach out to Jeff Tabor if you are interested! taborlab.rice.edu
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Come check out @hsalis and @PardeeLab talk about new work using synthetic biology to overcome challenges in COVID-19 diagnostics on April 16 at 3:00 pm CDT. Part of the new @Rice_BIOE Frontiers in Bioengineering Research Webinar series.
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Check out our new pre-print on optogenetic control of gut bacterial gene expression and metabolism in C. elegans. Great work by @SynbioLucas & Meng Wang (BCM). biorxiv.org/content/10.1101/…
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Congratulations to newly-minted Dr. Felix Ekness on his outstanding thesis defense! A truly impressive body of work on engineering and developing inhibitors for bacterial two-component systems.
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The first optogenetic tool for B. subtilis! Let us know if you want the strain. More great work by @castillohair. nature.com/articles/s41467-0…
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A new B. subtilis inducible promoter with >10,000 fold dynamic range! It's stringently off without IPTG and 50-fold more inducible than the widely used Phyperspank system. Get it from the Bacillus Genetic Stock Center. Congrats @castillohair! pubs.acs.org/doi/full/10.102…
Fun @LabTabor reunion at Momofuku Ssam Bar at SEED 2019 last night. We should do this every year!
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Check out our new paper about swapping bacterial two-component system DNA-binding domains so that they can be more easily studied and used for synthetic biology. nature.com/articles/s41589-0… Also the Behind the Paper blogpost bioengineeringcommunity.natu… Congrats @felixekness and team!
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