Medical biologist PharmD, PhD. Associate Professor @CHUToulouse. Passionate about #hematology #immunology hematopoietic stem cell #GATA2 🏔🎿
Toulouse, France
Joined November 2021
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Laetitia Largeaud retweeted
It’s CHO-time! Looking forward to meeting you all there!
🦄🎉 “IT’S TIIIIIIIMEE!”
Researchers Assemble!
It’s the most wonderful time of the year!
En route for the @CHO_HEMATO Annual Meeting! Let’s get ready to rumble about hematopoiesis and related malignancies.
Laetitia Largeaud retweeted
A map of mouse development from conception to birth tracks 12.4 million cells at single-cell resolution as they mature into organs and other tissues go.nature.com/3VtaN9u
Laetitia Largeaud retweeted
📢 Happy to announce our new review on stem cell #aging! We integrate traditional concepts/hallmarks of aging with emerging data on somatic evolution and stem cell competition. @NatureAging
nature.com/articles/s43587-0…
Laetitia Largeaud retweeted
🔬Job Opportunity Alert!🌟
Join our team as a Bioinformatician. If you're passionate about unraveling genomic mysteries and decoding biological data in blood disorders, this role is for you! Apply now! Deadline: 25/02/24 #Bioinformatics #ResearchJobs🧬💻
pro.idibell.cat/Convocatoria…
Laetitia Largeaud retweeted
👋 Hello 2024 - introducing nanoranger! 🐍
Are we ready to use @nanopore for tracking clonal evolution with #singlecell #genomics❓
Our manuscript provides vignettes on how, for example by tracking #AML during #immunotherapy
🔥🔥🔥
@NatureComms
nature.com/articles/s41467-0…
👇1/
Laetitia Largeaud retweeted
1/ 🔉Our lab is looking for two energetic and enthusiastic #postdocs 👩🔬🧑🔬 to study the causes and consequences of auto-Abs to type I IFNs (cell.com/cell/fulltext/S0092…). If you are interested, please write to [email protected] 📧 .
Laetitia Largeaud retweeted
Delighted to see the latest article leaded by @BastienGerby at @crctoncopole out in @JExpMed today. Glad to be part of this fruitful long term collaboration! More to come soon I hope 🤞 rupress.org/jem/article/221/…
Laetitia Largeaud retweeted
For anyone at #ASHG2023 check out our recent work led by superstar student @hamish_macg on modelling the deceleration of clonal haem in #UKBB. Cancer poster session III Saturday AM. Evidence of age-related slow down in HSC dynamics.
Very happy to have taken part in the 10th International symposium on MDS and SAA in Childhood in Lisbon 🇵🇹 with @marlene_pasquet . We are looking forward to seeing all the enthusiasts of these themes again soon. #gata2deficiency #iBMF #pediatricMDS
Thanks to the organizers #EWOG
Laetitia Largeaud retweeted
📢Clonal hematopoiesis driven by mCAs📢What fitness effects do mCAs confer to our blood cells?🩸 How often do they occur? Does an mCA’s fitness correlate with blood cancer risk?🔎Read mine & @jrblundell's latest paper @NatureGenet to find out (& more!):👉🔗rdcu.be/dlRRr
We are delighted to present our pre-print on the consequences of the GATA2 R396Q germline mutation on the hematopoietic stem cell compartment.
From embryogenesis to aging, this mutation quantitatively and functionally impacts HSPCs. 👉
Loss of HSC stemness identity is associated with exhaustion and hyporesponsiveness in GATA2 deficiency syndrome biorxiv.org/cgi/content/shor… #bioRxiv
Laetitia Largeaud retweeted
Today, we get to see IN PRINT what happens when the beauty of megakaryocytes and the brilliance of @nubama combine
I could not be more excited to share our publication, revealing that both MK maturation and platelet production rely on membrane PUFAs. 🧵👇
rdcu.be/dg3aH
Laetitia Largeaud retweeted
📢 Roll out the red carpet for our newest #bioRxiv preprint “Oncostatin M is a Master Regulator of an Inflammatory Network in Dnmt3a-Mutant Hematopoietic Stem Cells” by lead author & fantastic @TuftsGSBS PhD student @Logan_Schwartz1 🙌 1/n biorxiv.org/content/10.1101/…
Laetitia Largeaud retweeted
Labellisation Ligue Contre le Cancer de l'équipe IGAALD du @crctoncopole pendant 5 ans
➡️crct-inserm.fr/labellisation…
Laetitia Largeaud retweeted
🦄📣 Calling all blood-pumping enthusiasts! Join our running group of hematologists! You’re an RBC (Running Blood Cell) or a WBC (Wickedly Balanced Crawler)? There is a pace for everyone to run the extra mile together! #HematologyOnTheMove 🩸🏃♀️🏃♂️ Join here strava.app.link/y63QuoZNYAb
Laetitia Largeaud retweeted
What causes #ageing to our blood🩸?
Read our latest study @MolecularCell showing 🧬 DNA damage from aldehyde metabolites drive blood stem cell ageing via a p53 response.
cell.com/molecular-cell/full…
Wonderful collaboration of @ketanpatelimmo1 and @BertieGottgens labs! More below:
Laetitia Largeaud retweeted
Très heureux de clôturer, sous notre beau soleil sudiste, la 8eme promotion du DU de pédagogie médicale de @UnivLyon1 !
Laetitia Largeaud retweeted
Thank you to @EHA_Hematology for this superb congress #EHA2023 which as usual left us with lots of new ideas and new knowledge! We also made the most of the local culinary customs 🍻! It's also a great way to get together @GuillaumeInALab @Rathana_KIM_
🇪🇸 Madrid next year
