@MahulALM
 Switzerland
Joined December 2018
  • Tweets94
  • Following32
  • Followers41
Big thanks to @ionicwoman & @ozgungokce for helping shape my thoughts here. Also thanks to @DrNeuroChic @MahulALM & @MarkusBritschgi for all their input. And of course, thank you thank you @Hlashuel for the brilliant #latsis conference last week @EPFL tmrwedition.com/2022/09/05/r…

Re-Thinking The Multi-Hit Hypothesis of Neurodegenerative Diseases

And The Power of Patient Involvement

tmrwedition.com
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I'm in love ❤️😍🥰💞 ;) Seriously, thank you @MahulALM and to all here at the #Latsis symposium @EPFL who have embraced the call to put patients first.
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🎆 #Latsis symposium Patient Events!🎆 Meet the human faces of #neuro diseases and learn about the latest advances on treatments and disease modifying strategies More info: go.epfl.ch/Latsis Free Zoom seminars: go.epfl.ch/LatsisZoom See you at the Rolex Center @EPFL
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The Brain Mind Institute of the EPFL School of Life Science @epflSV is seeking to recruit two Tenure Track Assistant Professors with interest in brain (dys)function, neurodegeneration, regeneration, stem cells or organoids. 👉epfl.ch/about/working/facult… Please retweet.
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A novel mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein fibrils and recapitulates its pathological diversity biorxiv.org/cgi/content/shor… #biorxiv_neursci
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ALMahul retweeted
EPFL@EPFL16 Nov 2021
Une nouvelle étude de l’EPFL, annonce de nouvelles perspectives quant aux stratégies de traitement de à la maladie de Huntington. go.epfl.ch/ae92a3
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Replying to @Francoise_Clar @francetvsport @stade2
Merci Françoise🙏. C’est un travail d’équipe et la télévision suisse nous a beaucoup aidés. Le sujet doit surtout à la personnalité et au combat inspirant d’Yves Auberson @DefiParkinson 💪
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The structural basis of huntingtin (Htt) fibril polymorphism, revealed by cryo-EM of exon 1 Htt fibrils biorxiv.org/content/10.1101/…

The structural basis of huntingtin (Htt) fibril polymorphism, revealed by cryo-EM of exon 1 Htt...

The lack of detailed insight into the structure of aggregates formed by the huntingtin protein has hampered efforts to develop therapeutics and diagnostics targeting pathology formation in the brain...

biorxiv.org
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ALMahul retweeted
EPFL@EPFL21 Jul 2021
Why do @EPFL_en's scientists sometimes have to work with animals? This new site presents EPFL's animal facilities, how researchers work there, and under what conditions mice, rats and fish are housed. go.epfl.ch/10c3e0 @epflSV
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We are committed to help solve grand challenge of #ParkinsonsDisease through 🧠excellent, open, inclusive science 🧠collaborations with partners 🧠listening to #PwP and their families 🧠communicating our science to community #ParkinsonsDay youtu.be/za4AMS8gSWc

World Parkinson's Disease day 2021 - Lashuel lab (EPFL)

From understanding the pathology and how it forms, the Lashuel lab ...

youtube.com
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Postdoc position available in my lab to work on the regulation of proteostasis in the endoplasmic reticulum. Feel free to contact me directly or apply via the link below #Proteostasis #postdoc researchgate.net/job/950606_…
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Just out! 📃 Towards deciphering the Nt17 code: How the sequence and conformation of the first 17 amino acids in Huntingtin regulate the aggregation, cellular properties, and neurotoxicity of mutant Httex1 biorxiv.org/content/10.1101/…

Towards deciphering the Nt17 code: How the sequence and conformation of the first 17 amino acids in...

The first 17 N-terminal amino acids (the Nt17 domain) flanking the polyQ tract of the Huntingtin protein (Htt) play an important role in modulating its aggregation, life cycle, membrane binding, and...

biorxiv.org
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Towards deciphering the Nt17 code: How the sequence and conformation of the first 17 amino acids in Huntingtin regulate the aggregation, cellular properties, and neurotoxicity of mutant Httex1 biorxiv.org/cgi/content/shor… #bioRxiv
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#NYON Vous avez nommé Yves Auberson personnalité La Côte 2020. Nous sommes allés lui faire la surprise avec un cadeau chocolaté de Tristan de Perroy. Retrouvez sa réaction émue en vidéo. @EPFL @epflSV @DefiParkinson @LashuelLab @RegiondeNyon lacote.ch/dossiers/personnal…
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Lewy bodies are not just protein clumps, with complexity nicely shown by ⁦⁦@Hlashuel⁩ - and they occur in other rare diseases. What does this tell us? - link.springer.com/article/10…

Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders

Acta Neuropathologica - Accumulation of the protein α-synuclein into insoluble intracellular deposits termed Lewy bodies (LBs) is the characteristic neuropathological feature of LB diseases,...

link.springer.com
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💪⛰️ Malgré la maladie de Parkinson, Yves Auberson a relevé un incroyable défi: parcourir plus de 1000 km dans les Alpes suisses. Rencontre avec ce héros que rien n'arrête, demain dans #Stade2. 🔜 L'intégralité de ce reportage est à découvrir ce dimanche à 20h05 sur @France3tv.

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@DefiParkinson
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Dans Stade 2, ce dimanche à 20h05 sur @France3tv ⛵️@YannickBestaven et @CharlieDalin invités exceptionnels 🤾 Une troisième place pour les bleus ? 🏔 Yves Auberson : l’incroyable défi 🎙Matthieu @lartot @LaurentEric @FlorianRinguede @lefortmanu @pgolomer @guillaumepapin
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