Mathini Vaikunthan (@MathiniVai) profile picture

Mathini Vaikunthan

@MathiniVai

Princeton 2019 | BME Columbia

Joined July 2021
  • Tweets5
  • Following26
  • Followers17
2Media
Photo by Mathini Vaikunthan (@MathiniVai)Photo by Mathini Vaikunthan (@MathiniVai)
Mathini Vaikunthan retweeted
Lingting Shi (@shi_lingting) profile picture
Lingting Shi@shi_lingtingMar 3
Tumor immune evasion is programmable🛡️🧠. Our integrated single-cell CRISPR screening framework maps kinase control of T cell–driven tumor states in Glioblastoma(GBM) 🧬and nominates druggable nodes 💊 (e.g., EPHA2/PDGFRA) that blunt evasive programs and boost T cell killing 🔥.
Image from Lingting Shi (@shi_lingting)
3
40
3
132
13,302
Excited to share some of my PhD work! Here we present Targeted Reverse Transcription-Linker (TRTL), a modular method for scalable, targeted, combinatorial single-cell RNA-seq: biorxiv.org/content/10.64898…
Image from Mathini Vaikunthan (@MathiniVai)
2
4
4
14
1,827
We show how TRTL enables targeted-sci-Plex for massively multiplexed combinatorial indexing—enabling low-cost single cell profiling while maintaining the ability to resolve cell types and dynamic T-cell trajectories and clonotypes
Image from Mathini Vaikunthan (@MathiniVai)
Image from Mathini Vaikunthan (@MathiniVai)
1
2
217
Endlessly appreciative to my PI, @joselmcfaline , for always saying "go for it," and the co-authors on the study, especially Anna Schoonen, for all the long days brainstorming and implementing this method! biorxiv.org/content/10.64898…
3
117
Load more