Mattia Privitera retweeted
During moderate tonic locus coeruleus activation in mice, noradrenaline release engages cortical regions related to associative processing, while burst-like stimulation biases the brain toward sensory processing
nature.com/articles/s41593-0…
Mattia Privitera retweeted
Out now in @NatureNeuro: "Centripetal integration of past events in hippocampal astrocytes regulated by locus coeruleus", nature.com/articles/s41593-0…
With a great team: @FritjofHelmchen @BohacekLab @SianDuss @cloois and (twitterless) Denise Becker. 1/5
Mattia Privitera retweeted
🔵 Noradrenaline directly regulates gene expression in the brain. 8 years in the making, now finally published in @eLife 🥳
During revisions, we added 32 RNAseq samples and a meta-analysis of 71 RNAseqs to rule out major sex differences. #stress
Please RT
elifesciences.org/articles/8…
🚨🔵🚨
Our work on stress-induced gene expression changes mediated by #LocusCoeruleus #noradrenaline has now been reviewed by @eLife !🥳🤩
We got constructive and positive feedback 🙏, and we're tackling those pesky sex effects once more #revisions
elifesciences.org/reviewed-p…
Mattia Privitera retweeted
I am not on instagram but thanks to @SRF our PROTAC is @BohacekLab @MGazorpak @CarreiraGroup @bel_ethz @MiriamKretschm2 @SelinaJoyFrei
@iivanova0541
@MattiaPri instagram.com/reel/C2fnYdBOK…
srf.ch/play/tv/srf-news-vide…
Mattia Privitera retweeted
The first cellular map of a mammalian brain is here. 🧠✨
Over 6 years and 32 million cells in the making, the complete adult mouse brain cell-type atlas reveals astonishing diversity and regional specificity.
Dive deeper: alleninstitute.org/scientist…
@nature #studyBRAIN #BICCN
Mattia Privitera retweeted
A new review paper led by @mj_dahl, Agnieszka Kulesza and @WB_Markus. We review how deficient #dopaminergic and #noradrenergic modulation of hippocampal plasticity may contribute to memory loss in aging and Alzheimer's disease sciencedirect.com/science/ar… #locuscoeruleus
Mattia Privitera retweeted
That's all folks!
You gave me everything.
I gave you everything.
We did it together.
Mattia Privitera retweeted
🚨In our latest preprint🚨 we propose a radical change to the analysis of rodent #behavior in preclinical research.
Featuring @DeepLabCut ♥️
Check out the manuscript and the 🧵👇
nitter.gq/biorxiv_neursci/status…
Analysis of behavioral flow resolves latent phenotypes biorxiv.org/cgi/content/shor… #biorxiv_neursci
Mattia Privitera retweeted
1st preprint of the Gapplab! Check out our PROTAC tool to mingle with stress hormone receptor signalling A fun collaborative effort by @Carreiralab @BohacekLab @bel_ethz @Meijer_Lab @GermainPl
Lead by stellar students @MGazorpak & Karina Hungentobler biorxiv.org/content/10.1101/…
Mattia Privitera retweeted
🔵 In 2016 I wrote a grant, in which @MattiaPri and I asked a simple question:
Stress triggers massive transcriptional changes, which of them are dependent on noradrenaline (NA) signaling?
Today, we have the answer. But boy was this a journey. 🧵👇
biorxiv.org/content/10.1101/…
Mattia Privitera retweeted
New Nature paper provides evidence that science has become less innovative since the 1950s. The authors suggest reversing the trend by:
1. reading widely,
2. focusing less on quantity of papers, & more on research quality,
3. taking year-long sabbaticals.
nature.com/articles/s41586-0…
Mattia Privitera retweeted
For the first time, farmers in the #Philippines have cultivated #GoldenRice on a larger scale and harvested almost 70 tonnes of grains this October.This nearly never-ending story began at ETH Zurich. #betacarotene #vitaminA #HiddenHunger ethz.ch/en/news-and-events/e…
Mattia Privitera retweeted
The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics biorxiv.org/cgi/content/shor… #biorxiv_neursci
Mattia Privitera retweeted
The locus coeruleus mediates behavioral flexibility biorxiv.org/cgi/content/shor… #biorxiv_neursci
Mattia Privitera retweeted
Locus Coeruleus firing patterns selectively modulate brain activity and dynamics biorxiv.org/cgi/content/shor… #biorxiv_neursci
Mattia Privitera retweeted
NEW PREPRINT FROM THE LAB📢📢: Locus Coeruleus firing patterns selectively modulate brain activity and dynamics! 3y in the making and this work is finally seeing light thanks to a fantastic teamwork! C Grimm, S Duss and @BohacekLab. Short thread ⬇️ biorxiv.org/content/10.1101/…
Mattia Privitera retweeted
Very happy to share my lab’s new paper out in @PNAS. doi.org/10.1073/pnas.2116507…


















