@Mech_Morph_Lab

We study the molecular and biophysical mechanisms underlying tissue morphogenesis @PoLDresden @tudresden_de @ERC_Research @EMBO_YIP

 Arnoldstraße 18, 01307 Dresden
physics-of-life.tu-dresden.de/research/core-groups/barriga
Joined March 2020
  • Tweets1.6K
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  • Followers1.7K
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Our work on the role of endogenous electric fields in guiding collective cell migration in vivo is finally out @NatureMaterials ! nature.com/articles/s41563-0… Congrats to all the authors, specially Fernando and @Sofia__Moreira from my lab #bioelectrics #devbio #cellmigration #xenopus

Stretch-induced endogenous electric fields drive directed collective cell migration in vivo

Nature Materials - Electric fields guide collective cell migration in developing embryos of Xenopus laevis via a voltage-sensitive phosphatase.

nature.com
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📢 New ISRB Webinar — Morphogenesis and pattern formation Zone 1: Australia, East and South Asia 🗓 November 10, 2026 at 14:00 Asia/Shanghai 🎤 Kana Aoki 🎤 Toshimichi Yamada More info: isrbio.org/webinars
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Si eres entusiasta y riguros@, te interesan la genética y la evolución bacterianas, y tienes buen expediente (>8.5), considera solicitar un contrato FPU 2026 para unirte a nuestro laboratorio en @unisevilla. Si eres doctor, puedes optar a un contrato Juan de la Cierva. Enlaces:
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Bioengineering's gift to AI isn't another algorithm. It's more life-like cell cultures to learn from. LigHTS, now out in Advanced Science, makes soft, microstructured hydrogels directly in standard 1536-well plates, every well in a single 16-min light exposure. 🧵
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Barriga Lab retweeted
Xenbase@XenbaseOct 15
Xenopus oocytes contribute to the 2026 Nobel Prize in Medicine or Physiology. Drs. Nagel and Hegemann expressed channelrhodopsin-2 from single-celled algae in the oocytes. Light induces membrane channels to open. xenbase.org/xenbase/doNewsRe… #science #devbio #cellbio #xenopus #frogs
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Barriga Lab retweeted
Adam Cohen@AdamEzraCohenOct 13
We posted a preprint on all-to-all functional mapping of a cortical microcircuit in vivo. biorxiv.org/content/10.64898… Yitong Qi developed molecular tools, optics, and protocols for massively parallel optogenetic stimulation and voltage imaging during animal behavior.
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New Online! Towards a systematic understanding of the diverse subtypes, biogenesis and functions of large extracellular vesicles dlvr.​it/TVnJ7B
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Recently, preparing a talk made me think @ the impact of AI in #DevBio and led me to ask AI what would it do to explain the SM #organizer expt just w/ data w/o conceptual input from human interpretation of experiments. Its answer below 🧵
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📢 2027 ERC Consolidator Grant call for proposals is now open 📢 Have an excellent research idea and ready to build the team to pursue it? This funding could be for you! Deadline: 12 January 2027 👉 link.europa.eu/g4NrCc
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🚨I have open PhD positions to join my new lab at #NIMSB🚀!! nimsb.unl.pt/join-us/ 🌟I'm looking for motivated candidates, eager to join a multidisciplinary team + study the intracellular dynamics driving cancer cell migration with advanced computational methods & microscopy👾
🤖 Made with AI
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Barriga Lab retweeted
Peter Walentek@WalentekLabSep 20
Replying to @Nature
@Nature : why are you writing such misleading and wrong posts? Nobody thought there is only one cell, nobody thought all npcs are the same, so if you need that level of wrong to promote the paper, it's either nit novel enough or you have not understood what you are promoting. 👎
nature
@NatureSep 18
Many scientists have long thought that a single type of starter cell gives rise to the entire brain. But experiments now challenge that fundamental picture, providing evidence that it takes not one but two flavours of progenitor cell to make the complex organ. go.nature.com/4dJKmnY

How to make a brain: new experiments challenge existing picture

Nature - Research also uncovers an efficient way to grow hindbrain cells from stem cells — a difficult feat.

nature.com
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Congratulations @JoanaESaraiva and @SandraEdwJor on their new review on @embojournal we discussed few points about the coordination of cell state transitions in #embryo and #regeneration Also welcome to “X” @JoanaESaraiva link.springer.com/article/10…

Dynamic control of cell state transitions during tissue morphogenesis

The EMBO Journal - Morphogenesis, the process by which cells, tissues, and organs acquire and maintain their form, is essential for embryogenesis, regeneration, and disease progression. During...

link.springer.com
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Barriga Lab retweeted
Joel Boerckel@jboerckelSep 9
Our latest preprint, from @eerinberr is live: Cytoskeletal disassembly by optogenetic control of RhoA signaling termination. biorxiv.org/content/10.64898…
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Miki Ebisuya@EbisuyaMikiSep 9
I've just started my 2nd lab at RIKEN BDR in Kobe, Japan! This small, focused group will compare and manipulate species-specific time and shape, in collaboration with our Dresden lab. Interested in the stem cell zoo? Get in touch! bdr.riken.jp/en/research/lab…

Miki Ebisuya | Laboratory for Stem Cell Zoo

bdr.riken.jp
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Qian, @buenoscience et al reveal that proper spatial patterning of zygotic genome activation is required for embryogenesis & the existence of a surveillance system for embryo quality control exquisitely tuned to spatiotemporal ordering of genome activation hubs.la/Q04wXP8C0
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Miki Ebisuya@EbisuyaMikiSep 2
New paper from the lab! We developed a self-organizing muscle and blood vessel-like network from bovine ES cells, bringing us one step closer to creating structured cultured beef steak! 🥩🔬 nature.com/articles/s41467-0… 1/
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Adriano Aguzzi@AdrianoAguzziSep 1
Very honored and happy to serve as a Panel Chair for the current ERC AdG round. It's going to be a lot of work, but I will be seeing a lot of excellent science and will learn a mountain of new exciting things. erc.europa.eu/system/files/2…
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Jennifer Young@nano_jennSep 1
Excited to share our lab's new preprint led by Ting @huanting_ong introducing paired-surface spatial mechanomics! We link nanoindentation stiffness maps with #SpatialTranscriptomics to connect local tissue mechanics with molecular state. 🔗biorxiv.org/content/10.64898… 🧵1/7
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A developmental biologist's guide to mechanics | Development | The Company of Biologists journals.biologists.com/dev/…

A developmental biologist's guide to mechanics

Summary: A guide to mechanics in development: unlock how forces, material properties and geometry shape the forms of life.

journals.biologists.com
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🤔How does nature solve difficult physics problems? 🔬The group of Helmut Schießel studies the solutions to hard physics problems in the cell nucleus — from nuclear organization, to how DNA gets copied & sorted during cell division Watch our new video 👉youtube.com/watch?v=NrZXIjpB…
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Dr. Magdalena Sutcliffe and team at @CamBioCampus discovered a chemical chromatin restoration approach that reverses differentiation defects in hPSCs, restoring their ability to generate diverse cell types and brain #organoids. 📃 go.nature.com/4qhwOW8 Listen now: bit.ly/4xRQmD3
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