Marwin Gröner (@MedMarwin) header
Marwin Gröner (@MedMarwin) profile picture

Marwin Gröner

@MedMarwin

MD | Rheumatology Fellow at @JHRheumFellows | @YaleIMed & @unifau alumnus | Interested in novel therapeutics

 Baltimore, MD
Joined November 2019
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Photo by Marwin Gröner (@MedMarwin)Photo by Marwin Gröner (@MedMarwin)Photo by Marwin Gröner (@MedMarwin)Photo by Marwin Gröner (@MedMarwin)Photo by Marwin Gröner (@MedMarwin)Photo by Marwin Gröner (@MedMarwin)Photo by Marwin Gröner (@MedMarwin)Photo by Marwin Gröner (@MedMarwin)Photo by Marwin Gröner (@MedMarwin)Photo by Marwin Gröner (@MedMarwin)
One week left to submit your bracket for #RheumMadness ! Check out our scouting report on Bispecific T-cell engagers (tinyurl.com/2kzvsj5e). @jhrheumatology @MaxKonigMD
Bispecific T-cell engagers

Bispecific T-cell engagers

Team: Bispecific T-Cell Engagers (BiTEs), aka "Other Drugs BiTE the Dust" Base article: Alexander T, Krönke J, Cheng Q, Keller U, Krönke G. Teclistamab-Induced Remission in Refractory Systemic Lupus...

sites.duke.edu
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Marwin Gröner retweeted
Max Konig (@MaxKonigMD) profile picture
Max Konig@MaxKonigMD6 Feb 2025
What are the implications for CAR-T cell therapy for autoimmune diseases? 1- we need safety switches 2- we need targeted editing approaches, not just random integration 3- we need to favor therapies that are rejected (e.g., most allogenic CAR-T cells get rejected) All exist.
NEJM (@NEJM) profile pictureNEJM
@NEJM5 Feb 2025
A woman with multiply relapsed multiple myeloma had complete remission with cilta-cel, but a low-grade T-cell lymphoma soon developed in the GI tract that contained an insertion of the CAR construct disrupting expression of p53. Read the Brief Report: nej.md/40Yq3gO
Panel A: A dense lymphocytic infiltrate. Panel B: The infiltrate was positive for CD4 on immunohistochemical analysis. Panel C: p53 staining shows dim or absent expression in T-cell infiltrate. Panel D: Phosphorylated STAT3 (pSTAT3) immunohistochemical analysis shows positive staining.

ALT Panel A: A dense lymphocytic infiltrate. Panel B: The infiltrate was positive for CD4 on immunohistochemical analysis. Panel C: p53 staining shows dim or absent expression in T-cell infiltrate. Panel D: Phosphorylated STAT3 (pSTAT3) immunohistochemical analysis shows positive staining.

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Happy holidays from the @JHRheumFellows! @jhrheumatology #MerryChristmas2024 #HolidaySpirit
Image from Johns Hopkins Rheumatology Fellows (@JHRheumFellows)
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Thanks to our @JHRheumFellows for great #ACR24 wrap-ups at the MSRD meeting! @MedMarwin @RebeccaSlotkin @VishPatelMD
Image from Myma Albayda, MD, RhMSUS (@MymaAlbaydaMD)
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The holidays are in the air! The Rheumatology townhall never fails to put us in the 🎄 spirit! This year's program-- Two Truths a Lie (guess the lie!): 1. The @JHRheumFellows love their fellowship program 2. Rheumatologists are a bore 3. #Baltimore is beautiful in the winter
Image from Johns Hopkins Rheumatology Fellows (@JHRheumFellows)
Image from Johns Hopkins Rheumatology Fellows (@JHRheumFellows)
Image from Johns Hopkins Rheumatology Fellows (@JHRheumFellows)
Image from Johns Hopkins Rheumatology Fellows (@JHRheumFellows)
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Excited to present on the practice of rheumatology in Uganda at #ACR2024 today! Special thanks to @TradIMYale for their Global Health Scholars Program. @JHRheumFellows
Image from Marwin Gröner (@MedMarwin)
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Always such a fun time catching up with @jhrheumatology peeps at the Hopkins reunion at #ACR24! @DrLisaCS never fails to plan an amazing event! #pingpong #hopkins family
Image from Myma Albayda, MD, RhMSUS (@MymaAlbaydaMD)
Image from Myma Albayda, MD, RhMSUS (@MymaAlbaydaMD)
Image from Myma Albayda, MD, RhMSUS (@MymaAlbaydaMD)
Image from Myma Albayda, MD, RhMSUS (@MymaAlbaydaMD)
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Marwin Gröner retweeted
Max Konig (@MaxKonigMD) profile picture
Max Konig@MaxKonigMD17 Nov 2024
Congrats to Jin Liu for being awarded the ACR Emerging Investigator Excellence Award for her work on 9G4-targeted CAR/cTCR-T cells for the treatment of lupus. #ACR24 @jhrheumatology #ProundMentorMoment
https://acrabstracts.org/abstract/precision-targeting-of-autoreactive-9g4-b-cells-in-systemic-lupus-erythematosus-using-engineered-chimeric-antigen-receptor-car-and-chimeric-t-cell-receptor-ctcr-t-cells/

ALT https://acrabstracts.org/abstract/precision-targeting-of-autoreactive-9g4-b-cells-in-systemic-lupus-erythematosus-using-engineered-chimeric-antigen-receptor-car-and-chimeric-t-cell-receptor-ctcr-t-cells/

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We are so proud of our 2024 Hopkins award winners! @jhrheumatology Phil Seo - ACR Distinguished Service Award Kamini Kuchinad - ACR Distinguished Fellow Award Victoria Ruffing - ARP Award of Merit
Image from Myma Albayda, MD, RhMSUS (@MymaAlbaydaMD)
Image from Myma Albayda, MD, RhMSUS (@MymaAlbaydaMD)
Image from Myma Albayda, MD, RhMSUS (@MymaAlbaydaMD)
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Need a power/sample size calculation for a study or upcoming grant? Led by @emil_hs, we built a simple, free, and pain-free (!) shiny app. feedback welcome plz share with interested parties. check it out: powercalc.ca 🦾🤓 @sholzberg @kieranrcampbell @JeffsLianne @aaron_drucker @WallisCJD @NEJMEvidence @JonZipursky @ChanaSacks
Image from Michael Fralick (@FralickMike)
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After a few days of transitioning our new first year fellows through a "Crash Course in Rheumatology", they are off with a bang!@MedMarwin @RebeccaSlotkin @VishPatelMD #AntonioSalas #Rheumfellowship #newbies
Image from Johns Hopkins Rheumatology Fellows (@JHRheumFellows)
Image from Johns Hopkins Rheumatology Fellows (@JHRheumFellows)
Image from Johns Hopkins Rheumatology Fellows (@JHRheumFellows)
Image from Johns Hopkins Rheumatology Fellows (@JHRheumFellows)
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Marwin Gröner retweeted
DFA New Haven (@DFANewHaven) profile picture
DFA New Haven@DFANewHaven15 May 2024
Jimi Hendrix performing with the Isley Brothers at the Jazz Grotto on Howard Avenue in New Haven, circa 1964
Image from DFA New Haven (@DFANewHaven)
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Another interesting example of overcoming rituximab resistance with plasma cell-targeted therapy
Cravedi Lab (@cravedilab) profile pictureCravedi Lab@cravedilab14 Dec 2023
Efficacy of Combined Rituximab and Daratumumab Treatment in Post-Transplant Recurrent FSGS - American Journal of Transplantation amjtransplant.org/article/S1…
Efficacy of combined rituximab and daratumumab treatment in posttransplant recurrent focal segmen...

Efficacy of combined rituximab and daratumumab treatment in posttransplant recurrent focal segmen...

Focal segmental glomerulosclerosis (FSGS) is one of the leading causes of kidney failure and it is characterized by a high rate of recurrence after kidney transplant. Moreover, FSGS recurrence is...

amjtransplant.org
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Smiles all around at @TradIMYale! Congratulations to the @YaleIMed residents who matched into fellowship today and everyone entering GIM careers!
Image from Mark D. Siegel (@MarkDSiegel1)
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Very excited to join Johns Hopkins as a rheumatology fellow next year!
Johns Hopkins Rheumatology Fellows (@JHRheumFellows) profile pictureJohns Hopkins Rheumatology Fellows@JHRheumFellows29 Nov 2023
We are beyond thrilled to welcome a new class of amazing fellows to @jhrheumatology! @HopkinsMedicine We are so excited and look forward to working with all of you! @MedMarwin @VishPatelMD @RebeccaSlotkin @OslerResidency #FellowshipMatch #RheumatologyFellows #MatchDay
Image from Johns Hopkins Rheumatology Fellows (@JHRheumFellows)
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We are beyond thrilled to welcome a new class of amazing fellows to @jhrheumatology! @HopkinsMedicine We are so excited and look forward to working with all of you! @MedMarwin @VishPatelMD @RebeccaSlotkin @OslerResidency #FellowshipMatch #RheumatologyFellows #MatchDay
Image from Johns Hopkins Rheumatology Fellows (@JHRheumFellows)
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Shout out our brilliant #InternalMedicine residents presenting work at national conferences🎉! From cardiology to rheum, from GI to bioethics. Our residents can do it all! 🔬 Students and residents: check the thread for upcoming conferences that still are accepting abstracts!
Image from Yale IM Traditional Residency Program (@TradIMYale)
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Thanks to everyone who stopped by my poster today #ACR23. Looking forward to Day 2
Image from Marwin Gröner (@MedMarwin)
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So excited to attend my first #ACR23 meeting! Come by my poster tomorrow in the Thieves Market section and say hi
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