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MelanomaResearchPapers

@MelanRes_papers

Searching #PubMed for new publications from researchers studying novel therapeutic strategies for treating malignant melanoma. #Melanoma #Immunotherapy

 United States
Joined February 2018
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Microtubule destabilising activity of selected 7-methoxy-2-phenylbenzo[b]furan derivative against primary and metastatic melanoma cells dlvr.it/T0ZL3f
Microtubule destabilising activity of selected 7-methoxy-2-phenylbenzo[b]furan derivative against...

Microtubule destabilising activity of selected 7-methoxy-2-phenylbenzo[b]furan derivative against...

Herein, we report the results of anticancer screening of two 2-phenylbenzo[b]furan derivatives functionalised at the 3-position with 4-hydroxy-3,5-dimethoxybenzoyl (BF2) or 3,4,5-trimethoxybenzoyl...

pubmed.ncbi.nlm.nih.gov
40
c-Met+ Cytotoxic T Lymphocytes Exhibit Enhanced Cytotoxicity in Mice and Humans In Vitro Tumor Models dlvr.it/T0Z93H
c-Met+ Cytotoxic T Lymphocytes Exhibit Enhanced Cytotoxicity in Mice and Humans In Vitro Tumor...

c-Met+ Cytotoxic T Lymphocytes Exhibit Enhanced Cytotoxicity in Mice and Humans In Vitro Tumor...

CD8+ cytotoxic T lymphocytes (CTLs) play a crucial role in anti-tumor immunity. In a previous study, we identified a subset of murine effector CTLs expressing the hepatocyte growth factor (HGF)...

pubmed.ncbi.nlm.nih.gov
28
Targeting of the NOX1/ADAM17 Enzymatic Complex Regulates Soluble MCAM-Dependent Pro-Tumorigenic Activity in Colorectal Cancer dlvr.it/T0Z2BJ
Targeting of the NOX1/ADAM17 Enzymatic Complex Regulates Soluble MCAM-Dependent Pro-Tumorigenic...

Targeting of the NOX1/ADAM17 Enzymatic Complex Regulates Soluble MCAM-Dependent Pro-Tumorigenic...

The melanoma cell adhesion molecule, shed from endothelial and cancer cells, is a soluble growth factor that induces tumor angiogenesis and growth. However, the molecular mechanism accounting for its...

pubmed.ncbi.nlm.nih.gov
25
Prevalence of RAF1 Aberrations in Metastatic Cancer Patients: Real-World Data dlvr.it/T0YtPv
Prevalence of RAF1 Aberrations in Metastatic Cancer Patients: Real-World Data - PubMed

Prevalence of RAF1 Aberrations in Metastatic Cancer Patients: Real-World Data - PubMed

We demonstrated that approximately 2.0% of patients with metastatic solid cancers have RAF1 aberrations according to NGS of tumor specimens.

pubmed.ncbi.nlm.nih.gov
18
CD200/CD200R: Bidirectional Role in Cancer Progression and Immunotherapy dlvr.it/T0YjwS
CD200/CD200R: Bidirectional Role in Cancer Progression and Immunotherapy - PubMed

CD200/CD200R: Bidirectional Role in Cancer Progression and Immunotherapy - PubMed

As an immune checkpoint molecule, CD200 serves a foundational role in regulating immune homeostasis and promoting self-tolerance. While CD200 expression occurs in various immune cell subsets and...

pubmed.ncbi.nlm.nih.gov
30
Desmoid Tumors in the Active Surveillance Era: Evaluation of Treatment Options and Pain Relief in a Single-Center Retrospective Analysis dlvr.it/T0YVfl
Desmoid Tumors in the Active Surveillance Era: Evaluation of Treatment Options and Pain Relief in a...

Desmoid Tumors in the Active Surveillance Era: Evaluation of Treatment Options and Pain Relief in a...

In patients with desmoid tumors (DTs), active surveillance has been increasingly preferred over surgery, while treatment (including pharmacological therapy, radiotherapy, and/or surgery) is performed...

pubmed.ncbi.nlm.nih.gov
29
Do Tumor SURVIVIN and MDM2 Expression Levels Correlate with Treatment Response and Clinical Outcome in Isolated Limb Perfusion for In-Transit Cutaneous Melanoma Metastases? dlvr.it/T0YG3y
Do Tumor SURVIVIN and MDM2 Expression Levels Correlate with Treatment Response and Clinical Outcome...

Do Tumor SURVIVIN and MDM2 Expression Levels Correlate with Treatment Response and Clinical Outcome...

Isolated limb perfusion (ILP) involves the local administration of high doses of anticancer drugs into a limb affected by unresectable locally advanced tumors (with special regard to in-transit...

pubmed.ncbi.nlm.nih.gov
32
Evaluation of the Antitumor Activity of Quaternary Ammonium Surfactants dlvr.it/T0Y20G
Evaluation of the Antitumor Activity of Quaternary Ammonium Surfactants - PubMed

Evaluation of the Antitumor Activity of Quaternary Ammonium Surfactants - PubMed

Quaternary ammonium surfactants, due to their diverse chemical structure and their biological properties, can be used in medicine as DNA carriers, disinfectants, and antimicrobial and antitumor...

pubmed.ncbi.nlm.nih.gov
16
Current Status and Molecular Mechanisms of Resistance to Immunotherapy in Oral Malignant Melanoma dlvr.it/T0XpMt
Current Status and Molecular Mechanisms of Resistance to Immunotherapy in Oral Malignant Melanoma -...

Current Status and Molecular Mechanisms of Resistance to Immunotherapy in Oral Malignant Melanoma -...

Immune checkpoint inhibitors (ICIs), including anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and anti-programmed death-1 (PD-1) antibodies, have initiated a new era in the treatment of...

pubmed.ncbi.nlm.nih.gov
28
Photodynamic Therapy Directed to Melanoma Skin Cancer by Thermosensitive Hydrogel Containing Chlorophyll A dlvr.it/T0XVBN
Photodynamic Therapy Directed to Melanoma Skin Cancer by Thermosensitive Hydrogel Containing...

Photodynamic Therapy Directed to Melanoma Skin Cancer by Thermosensitive Hydrogel Containing...

Melanoma, a severe form of skin cancer intricately linked to genetic and environmental factors, is predicted to reach 100,000 new cases worldwide by 2040, underscoring the need for effective and safe...

pubmed.ncbi.nlm.nih.gov
29
The predictive efficacy of programmed cell death in immunotherapy of melanoma: A comprehensive analysis of gene expression data for programmed cell death biomarker and therapeutic target discovery dlvr.it/T0XLhw
The predictive efficacy of programmed cell death in immunotherapy of melanoma: A comprehensive...

The predictive efficacy of programmed cell death in immunotherapy of melanoma: A comprehensive...

In this study, genes linked to prognosis in skin cutaneous melanoma (SKCM) involved in programmed cell death (PCD) were identified and confirmed and prognostic models based on these genes were...

pubmed.ncbi.nlm.nih.gov
27
MDSC suppresses T cell antitumor immunity in CAC via GPNMB in a MyD88-dependent manner dlvr.it/T0X9Bv
MDSC suppresses T cell antitumor immunity in CAC via GPNMB in a MyD88-dependent manner - PubMed

MDSC suppresses T cell antitumor immunity in CAC via GPNMB in a MyD88-dependent manner - PubMed

MyD88 signaling pathway plays an essential role in GPNMB+MDSC-mediated tumor immune escape during CAC development and is a promising focus for revealing the mechanisms of MDSC that facilitate...

pubmed.ncbi.nlm.nih.gov
29
Electrochemical Nanopipette Sensor for In Vitro/In Vivo Detection of Cu2+ Ions dlvr.it/T0WxSC
Electrochemical Nanopipette Sensor for In Vitro/In Vivo Detection of Cu2+ Ions - PubMed

Electrochemical Nanopipette Sensor for In Vitro/In Vivo Detection of Cu2+ Ions - PubMed

In vitro/in vivo detection of copper ions is a challenging task but one which is important in the development of new approaches to the diagnosis and treatment of cancer and hereditary diseases such...

pubmed.ncbi.nlm.nih.gov
18
Cancer risk with biologic and targeted synthetic DMARDs in patients with rheumatic diseases and previous malignancies: Results from the BIOBADASER register dlvr.it/T0Wh1q
Cancer risk with biologic and targeted synthetic DMARDs in patients with rheumatic diseases and...

Cancer risk with biologic and targeted synthetic DMARDs in patients with rheumatic diseases and...

We did not find differences in the risk of incident cancer in patients with rheumatic diseases and a previous malignancy between TNFi and other b/tsDMARDs. While incident cancers in our cohort were...

pubmed.ncbi.nlm.nih.gov
13
Selection of patients with malignant melanoma for pelvic lymph node dissection (PLND) using CT-PET dlvr.it/T0WQnt
Selection of patients with malignant melanoma for pelvic lymph node dissection (PLND) using CT-PET...

Selection of patients with malignant melanoma for pelvic lymph node dissection (PLND) using CT-PET...

The 2010 guidelines remain broad and contributed to negative PLND in a third of our patients (9/26). Hence, the indications for performing PLND need to be revisited. Our series supports PET-CT as...

pubmed.ncbi.nlm.nih.gov
25
Iodine-125 brachytherapy for choroidal melanoma by using Ocuprosta seeds with indigenous non-collimated plaques: Our initial experience dlvr.it/T0WBV5
Iodine-125 brachytherapy for choroidal melanoma by using Ocuprosta seeds with indigenous non-coll...

Iodine-125 brachytherapy for choroidal melanoma by using Ocuprosta seeds with indigenous non-coll...

Iodine-125 brachytherapy with uncollimated indigenous gold plaques is an effective treatment modality for choroidal melanomas in Asian patients.

pubmed.ncbi.nlm.nih.gov
28
Expression of Preferentially Expressed Antigen in Melanoma, a Cancer/Testis Antigen, in Carcinoma In Situ of the Urinary Tract dlvr.it/T0Vzr4
Expression of Preferentially Expressed Antigen in Melanoma, a Cancer/Testis Antigen, in Carcinoma...

Expression of Preferentially Expressed Antigen in Melanoma, a Cancer/Testis Antigen, in Carcinoma...

Carcinoma in situ (CIS) of the urinary tract comprises 1-3% of all urothelial malignancies and is often a precursor to muscle-invasive urothelial carcinoma (UC). This study aimed to examine the...

pubmed.ncbi.nlm.nih.gov
26
Objective response rate and progression-free survival as surrogates for overall survival treatment effect: A meta-analysis across diverse tumour groups and contemporary therapies dlvr.it/T0VqKn
Objective response rate and progression-free survival as surrogates for overall survival treatment...

Objective response rate and progression-free survival as surrogates for overall survival treatment...

ORR and PFS were poor trial-level surrogate markers of OS. The surrogacy performance of ORR and PFS differed by treatment and malignancy sub-type.

pubmed.ncbi.nlm.nih.gov
10
Kazachstania pintolopesii in Blood and Intestinal Wall of Macrophage-Depleted Mice with Cecal Ligation and Puncture, the Control of Fungi by Macrophages during Sepsis dlvr.it/T0VfVB
Kazachstania pintolopesii in Blood and Intestinal Wall of Macrophage-Depleted Mice with Cecal...

Kazachstania pintolopesii in Blood and Intestinal Wall of Macrophage-Depleted Mice with Cecal...

Although macrophage depletion is a possible emerging therapeutic strategy for osteoporosis and melanoma, the lack of macrophage functions can lead to inappropriate microbial control, especially the...

pubmed.ncbi.nlm.nih.gov
19
Porokeratoses-A Comprehensive Review on the Genetics and Metabolomics, Imaging Methods and Management of Common Clinical Variants dlvr.it/T0VQc5
Porokeratoses-A Comprehensive Review on the Genetics and Metabolomics, Imaging Methods and Manage...

Porokeratoses-A Comprehensive Review on the Genetics and Metabolomics, Imaging Methods and Manage...

Porokeratosis is a heterogeneous group of keratinising disorders characterised by the presence of particular microscopic structural changes, namely the presence of the cornoid lamella. This structure...

pubmed.ncbi.nlm.nih.gov
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