@MetaStem_Center

Centre of Excellence in Stem Cell Metabolism 2018-2025 @KatajistoLab @HTyynismaa @HietakangasLab @OtonkoskiL @JetteLeng https://xitter.cf/t.co/xszN6BWQvl

 Helsinki, Finland
bsky.app/profile/metastem.bsky.social
Joined October 2017
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139Media
Welcome to the PhD defense of @_HienBui Age-selective segregation of organelles in asymmetric stem cell division, on Fri 7 Nov at 1 pm, Biocenter 2, 2041. Opponent Prof Carien Niessen, University of Cologne @helsinkiuni @HiLIFE_helsinki @MIBS_Helsinki #publicdefense #phddefense
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Proudly presenting Simon’s paper on asymmetric apportioning of old mitochondria biasing intestinal stem cells for the Paneth cell linage through aKG-dependent metabolism @NatMetabolism nature.com/articles/s42255-0… @helsinkiuni @HiLIFE_helsinki @SuomenAkatemia @MetaStem_Center

Old mitochondria regulate niche renewal via α-ketoglutarate metabolism in stem cells

Nature Metabolism - Andersson et al. show that intestinal stem cells enriched for old mitochondria are metabolically distinct and have enhanced ability to regenerate the epithelial niche.

nature.com
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Happy to present Hien’s paper on age-selective apportioning of peroxisomes as a fate determinant in adult stem cells nature.com/articles/s41467-0… @MetaStem_Center @helsinkiuni @karolinskainst @BIOTECH_UH @MIBS_Helsinki @SuomenAkatemia out now in @NatureComms Congrats @_HienBui et al!

Glucose-6-phosphate-dehydrogenase on old peroxisomes maintains self-renewal of epithelial stem...

Nature Communications - Peroxisomes are essential but their role in cell fate regulation remains understudied. Here, the authors reveal that young and old peroxisomes are not equally distributed in...

nature.com
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Next Stem Cell Seminar April 23rd, welcome! bsky.app/profile/metastem.bs… @HelsinkiUniMed @HiLIFE_helsinki @STEMMProgram @BIOTECH_UH @FIMM_UH
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The @KatajistoLab modeled #epithelial regeneration using small intestinal scaffolds and identified #asporin is a mediator of fetal-like reprogramming. Read the @CellStemCell article: bit.ly/41LJbhn Listen to the conversation: bit.ly/3FBkNHR
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Welcome to the next Metabolism seminar, March 18th at 9-11 am in Meilahti. Excellent speaker lineup with and @DrPietilainen and Robin Cristofari groups presenting about #obesity #adiposetissue #diet #aging in humans and penguins @STEMMProgram @BIOTECH_UH @HelsinkiUniMed
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Online Now! Fetal-like reversion in the regenerating intestine is regulated by mesenchymal asporin dlvr.it/TJMj7h #stemcells
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Proudly presenting Sharif’s paper on the role of Asporin in intestinal regeneration through TGF-B-dependent fetal-like reversion sciencedirect.com/science/ar… out now in @CellStemCell @helsinkiuni @SuomenAkatemia @BIOTECH_UH @MIBS_Helsinki @PekkaKatajisto Read our thread on Bluesky🦋
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Welcome @ChristianGoritz on Jan 23rd. Excited to hear about your research on perivascular fibroblasts, scarring and regeneration of the central nervous system. The seminar is part of the Stem Cell Seminar series and open to all @LifeSciHelsinki @HelsinkiUniMed @HiLIFE_helsinki
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💥Postdoc position open for highly motivated enthusiast of hematopoietic stem cells at Karolinska Institutet @karolinskainst in Sweden 🇸🇪Link here: ki.varbi.com/what:job/jobID:… Please RT We are excited for your application!😃

Postdoctoral Researcher in human stem cells

Do you want to contribute to top quality medical research? Are you interested in how human stem cells contribute to aging and disease? The failure to regenerate tissue with age is a major health issue

ki.varbi.com
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💥Technician position open for highly motivated enthusiast of hematopoietic stem cells at Helsinki University @BIOTECH_UH @HiLIFE_helsinki in the happiest country of the world: Finland! 🇫🇮Link here: lengefeldlab.com Please RT 😃
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Finishing the year with 1st preprint from the lab! Together with @KatajistoLab and @ValerioIzzi we investigated the role of basement membrane protein Lama5 and found it is critical for luminal breast cancer initiation and growth biorxiv.org/content/10.1101/…

Tumour-derived LAMA5 is critical for tumour initiation and controls progression and phenotype in...

Basement membrane (BM) supports and regulates the structural integrity, function and differentiation of epithelial tissues and protects against stromal invasion of breast cancer cells. Here we show...

biorxiv.org
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One of three #postdoc openings available in the lab. Funded by @FIMM_UH @NordicEMBL and by @Syopasaatio @HiLIFE_helsinki
FIMM HelsinkiUni@FIMM_UH16 Dec 2024
FIMM is seeking a postdoctoral researcher in functional cancer microbiome to join the @Rafabolism lab, in collaboration with Chinmay Dwibedi’s group at @mims_umea, through the NORPOD program of the @NordicEMBL partnership. jobs.helsinki.fi/job/Helsink… #postdocposition #sciencejobs
A large blue chromosome and the logos of FIMM, University of Helsinki & the Nordic EMBL Partnership, with the title of the open position and text "Apply by 24 Jan".

ALT A large blue chromosome and the logos of FIMM, University of Helsinki & the Nordic EMBL Partnership, with the title of the open position and text "Apply by 24 Jan".

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📣 Job alert! We are recruiting for a #postdoc in functional #genomics and #cancer research together with @Sahu_B lab. Chance to work in Helsinki&Oslo.
NCMBM@NCMBMnews6 Dec 2024
📣 Job alert! The @Sahu_B group is recruiting for a #postdoc in functional genomics and cancer research and #NORPOD #postdoc in cancer epigenomics: a collaboration with @Rafabolism @FIMM_UH 👉tinyurl.com/eb2vpxxx @NordicEMBL @NordicEMBL
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Excited to share our latest paper on IER3IP1 role in ER-to-Golgi trafficking of proinsulin in human beta cells! Using SC-islets and high-resolution live-cell imaging, we’ve uncovered the pathogenic mechanism behind IER3IP1 mutations causing #diabetes. doi.org/10.2337/db24-0119
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I am grateful to @novonordiskfond for funding a project grant to understand the mechanism for differential vulnerability of alpha and beta cells in #T1D through stem cells islets; looking for a motivated #postdoc ! @HelsinkiUniMed @helsinkiuni #Type1diabetes
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What an unforgettable day! Successfully defended my PhD after an inspiring examination by Prof. Raphael Scharfmann. Grateful for this huge milestone, and for the incredible support of my supervisor, colleagues, family and friends. #PhDComplete #OnToTheNextChapter
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Swetha @SwethaGopalakr2 and Emilia @EmiliaKuul representing the lab at @Fusion_Conf Metbolism in Health and Disease #MHD24 Swetha has a talk later today on organelle asymmetry and metabolism in stem cell fate regulation @MetaStem_Center
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🥳🥳The whole lab is thrilled and thankful for the prestigious @SuomenAkatemia project funding to study size-related stem cell functions and @EHA_Hematology Innovation Grant funding for our MorphoSCREEN project!! @HiLIFE_helsinki @karolinskainst
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#HiringNow: #Postdoc positions open for enthusiasts of pancreas development, #stem cell-derived islets and #diabetes at our new lab @helsinkiuni @HelsinkiUniMed @STEMMProgram . Join our team in Finland 🇫🇮, happiest country in the world! Apply by 15.10.24: jobs.helsinki.fi/job-invite/…

Postdoctoral Researcher on Genome Regulation of Islet Cell Development

Postdoctoral Researcher on Genome Regulation of Islet Cell Development

jobs.helsinki.fi
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