Montagne lab @EdinburghUni. We 🇲🇽🇸🇰🇺🇸🇬🇧🇭🇺🇨🇿🇨🇴🇮🇪🇪🇸🇪🇨🇦🇺🇫🇷🇲🇴🇳🇴🇳🇬🏴🇲🇦🇦🇷🇺🇦 study the blood vessels 🩸 in the brain 🧠
Edinburgh
Joined April 2021
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Montagne Lab retweeted
Thrilled to share our new study showing how CSF crosses through arachnoid fenestrations to olfactory meningeal lymphatics: Cell cell.com/cell/fulltext/S0092… A major step toward understanding CSF exit from subarachnoid space.
Montagne Lab retweeted
Disease causing mutations in each of these 11 genes are implicated in at least three different chronic diseases or lifespan in humans. #Aging #Longevity #Genetics
nature.com/articles/s41576-0…
Montagne Lab retweeted
🚨 New preprint
11,000+ human brain microvessels in cSVD
• Early bimodal pericyte loss
• Later endothelial activation w/ a venous-like inflammatory shift
• ↑ capillary density with disease
💡 Suggests sequential vascular pathology, not parallel
🔗 shorturl.at/KZapP
Montagne Lab retweeted
Here is the FindAPhD weblink to our BHF-DRI PhD programme!
Deadline: *April 14*
Please spread the word!!
eur02.safelinks.protection.o…
Montagne Lab retweeted
🚨 PhD Programme – Vascular Dementia Research
New 4-year PhD funded by BHF & UK DRI.
Training across UCL, Oxford, Leicester & Edinburgh with lab rotations.
📅 Deadline: 14 April
🎓 Start: Sept 2026
Apply: CV + statement + 2 refs > [email protected]
Please share!
Montagne Lab retweeted
The “exerkine” GPLD1 confers cognitive benefit by removing an alkaline phosphatase from blood vessel walls, keeping brain vasculature youthful. #alzheimersdisease @UCSF ow.ly/wAS050Yngak
Montagne Lab retweeted
Scientists identified 49 proteins genetically linked to cerebral small vessel disease. This common co-pathology with #alzheimersdisease contributes to risk for ARIA. @wustl @UTokyo_News ow.ly/OrKw50XxE0n
Montagne Lab retweeted
Excited to share our @CurrentBiology Primer written with @AudreyChagnot in the Brain-Body Interactions special issue!
We discuss how the BBB works, what happens when it breaks down, and why this matters for brain and body health.
@UKDRI @TheBHF
shorturl.at/NNc57
Montagne Lab retweeted
🎉 This week, we’re proud to officially launch the BHF-UK DRI Centre for Vascular Dementia Research, in partnership with @TheBHF.
The centre will explore how changes in vascular health contribute to dementia - paving the way for new treatments👉 buff.ly/5ZEjQx8
Montagne Lab retweeted
🌟 New job opportunity 🌟
Based within the UK DRI at Edinburgh, the Rajani Lab investigates the mechanisms of white matter damage in vascular and other dementias.
Find out more and apply via the link
🗓️ Apply by 22 October 2025
📌 Full details 👉 tinyurl.com/22y73642
Montagne Lab retweeted
✨ Preorders are OPEN ✨
My amazing wife just finished her very first children’s book, and I couldn’t be prouder 💛
📚 Preorder until Sept 7
📦 Shipped w/ tracking
🔗 etsy.com/shop/ElodieWho
She’s poured her heart into this — every preorder, share, & boost means the world 🙌
Montagne Lab retweeted
The first patient in Phase 1b trial for Alzheimer's disease has been dosed with the fibrin-targeting immunotherapy. I am deeply grateful to the patients, clinical centers, the team at Therini Bio, and all the scientists in my lab making the foundational discoveries on fibrin in neurological diseases and the first-in-class fibrin-targeting antibody. globenewswire.com/fr/news-re…
Montagne Lab retweeted
🚨 Review Alert
*Walking on the tightrope: the shared roles of the bridging pericytes in the brain*
Congratulations Audrey Chagnot!! 🥳
Bias aside, this feels like a really meaningful piece for the cerebrovascular field! 😊
frontiersin.org/journals/cel…
Montagne Lab retweeted
Well done @DanyJaimeGarcia 👏🤩
Blood biomarkers of vascular dysfunction in small vessel disease progression: Insights from a longitudinal neuroimaging study - Jaime Garcia - 2025 - Alzheimer's & Dementia - Wiley Online Library alz-journals.onlinelibrary.w…
Montagne Lab retweeted
We have a @TheBHF funded postdoc position to work on a novel treatment option to improve cerebral blood flow in a model of vascular dementia. Application deadline 14th April. @GJBrainResearch @DCVS_UoM. Please RT jobs.manchester.ac.uk/intern…
Montagne Lab retweeted
Another @wysscoray & @StephenQuake labs collaboration! 🔬 With @HenzeDoug, we identify a subtype of disease-associated microglia with a ramified morphology, challenging conventional assumptions between cellular morphology and microglial states.🧠#Microglia biorxiv.org/content/10.1101/…
Montagne Lab retweeted
Fascinating new research by @adrianisaacslab reveals that enhancing levels of “healthy fats” like omega-3s in the brain could be beneficial in motor neuron disease🧠
The study offers new understanding to back up previous epidemiological studies in MND👉 buff.ly/3XeVQI4
Montagne Lab retweeted
We are excited to begin our international search for a new Centre Director at the UK DRI at Cardiff University! 🏴
Help shape scientific priorities alongside your own research programme in neurodegeneration
🗓️Closing date: 20 March
Find out more 👉 ukdri.ac.uk/vacancies/centre…
Montagne Lab retweeted
🚨 Check out our latest contribution where we delve into the dementia-related snRNA-seq data and spotlight the signature changes in brain #endothelialcells and #pericytes!
Very proud of the effort led by Dr. Michael Sewell and Nela Fialova @fialovanel.
alz-journals.onlinelibrary.w…
Montagne Lab retweeted
Brain macrophages in vascular health and dysfunction sciencedirect.com/science/ar…