Translational Pain Research Laboratory | Chronic Primary Pain Conditions | β3-adrenergic Receptor | Account does not represent opinion of Duke

Durham, NC
Joined July 2021
For more information on our lab's work to understand the mechanisms of chronic pain, visit our lab website at: tinyurl.com/NackleyLab
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Congratulations to Osman on being awarded the Laffitte Undergraduate Research Grant in Psychology and Neuroscience! 🎉 We’re proud to see his dedication to research recognized and look forward to seeing where his work takes him in his senior thesis! psychandneuro.duke.edu/lafit…
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Please join us in welcoming Dr. James Coy-Dibley, our newest postdoc! James recently completed his PhD in Neuroscience at Northwestern, studying extracellular vesicles and painful diabetic neuropathy. We’re thrilled to welcome him and his family to the area and our lab! 🎉
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🏆 Big congratulations to Dr. Nackley on an incredible finish at the OBX Olympic Distance Triathlon this past Saturday! She took 1st place overall among women in the Olympic-distance race! 🏊‍♀️🚴‍♀️🏃‍♀️
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More exciting news from our lab! 🎉 We’re thrilled to share our latest paper in JCI, identifying adipocyte-derived miR-133a-3p as a regulator of chronic primary pain. Increasing its expression reversed pain hypersensitivity in mice! Read the full study: jci.org/articles/view/197345
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Excited to announce that the Nackley Lab has been awarded a $3 million NIH R01 grant, building on research led by our own Dr. Nathaniel Hernandez (right)! Learn about the team’s work on how fat cells communicate with the nervous system to influence pain: anesthesiology.duke.edu/news…
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🎉 Congratulations to our two undergraduate researchers, Sunny and Osman, on successfully completing the Summer Neuroscience Program! We’re proud of your hard work and contributions to the lab. Wishing you continued success in your future research and academic endeavors! 👏🧠
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New publication! 🎉 Why do some older adults experience more chronic pain after surgery than others? Our latest paper found that higher preoperative cerebrospinal fluid TRAIL was associated with lower 1-year postsurgical pain severity. Read more here: qa-hub2.ovid.com/10.1213/ANE…
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We’re proud to share that Sara Lin presented her Biology senior thesis from our lab: “Molecular and Clinical Features Associated with Comorbid Chronic Primary Pain in Obesity.” Wishing you the best as you head to medical school at WashU! Congratulations!
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We were honored to have our very own Dr. Nackley speak at the Center for Advanced Pain Therapeutics & Research (CAPToR) at @UF. Thank you to Dr. Raj Khanna (@KhannaLabUF) for the award, and to Rana and the CAPToR team for an amazing visit.
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Dr. Andrea Nackley was featured in the 2026 Benign Urology Symposium at Duke School of Medicine—an exciting opportunity to share the lab's work in vestibulodynia!
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Check out our Special Issue in Pain Reports on the Epigenetic Regulation of Chronic Pain, with Dr. Nackley as the guest editor! journals.lww.com/painrpts/pa…
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More great news from the lab! 🎉 Sunny Hsiung, a sophomore, was accepted to Duke’s Summer Neuroscience Program: bassconnections.duke.edu/sum… She’ll lead a project on adrenergic sensitivity in altered adipocytes as a model for obesity and pain sensitivity. Way to go, Sunny!
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A proud moment for our lab! 👏 Dr. Andrea Nackley delivered the keynote at @UNCDentistry’s 42nd Annual Dental Research Day and was honored with an award recognizing her outstanding contributions. Thank you to Dr. Seth Weinburg for presenting this special recognition!
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Happy holidays! Overjoyed to have lab members and alumni able to gather in celebration!
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Thrilled to share that Dr. Nackley has been selected as a 2026 USASP Fellow! Huge congratulations on this well-earned honor 🎉
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We collected nearly 80 pounds of trash and recycling from Erwin road today in our annual trash pickup with @DurhamBeautiful!
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Dr. Nackley will be presenting in the UT Dallas seminar series this Thursday on the Neuro-adipo-immune axis of chronic primary pain. Looking forward to a great discussion!
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It was so wonderful to attend the St. Louis Translational Pain Research Forum this past weekend!
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