Nieng Yan retweeted
Announcing 📣 the 2022 Blavatnik Regional Awards Honorees🏅! Congratulations! 👏👏👏 blavatnikawards.org/news/ite… #NPAW2022 @nationalpostdoc
@danbburg @BrookhavenLab @RosemaryJCater @Columbia @ColumbiaMed @SimonsFdn @xiaohutugs @Princeton @princetonideas @NiengYan @WHUni_Official
Finally, here is the structure of GLUT4! No nanobody, no antibody — Just a 12-TM SLC by Cryo-EM! Thanks to my incredible collaborator Chuangye Yan nature.com/articles/s41467-0…
Truly honored!
Nieng Yan of @PrincetonMolBio conducts groundbreaking research into atomic-resolution molecular choreography, revealing the physiological and cellular processes involving membrane transport.
Watch her induction to the National Academy of Sciences: ow.ly/Cg5c50IVpAA #NAS159
My first in-person meeting since March 2020. So nice to catch up with friends!
The unstoppable @NiengYan delivers a tour de force of ion channel structure after structure after structure…whew! She is amazing. @MembraneMeeting #Banff
First publication in the new year. Here is a free access to the full text of our review article before Feb 26 authors.elsevier.com/a/1eNXw… Congratulations and thanks to my wonderful co-authors!
Finally, we captured a different conformation of a Cav channel -- the N-type Cav2.2 in complex with Ziconotide, a peptide painkiller. Very proud of my brilliant postdocs Shuai and Xia rdcu.be/cnVxR
Congratulations to my former postdoc Jianping Wu on the landmark structure of CatSper (Catspermasome) rdcu.be/cnMyF
Nieng Yan retweeted
Another interesting example of AI structure prediction aiding #cryoem structure solution. Here @NiengYan @PrincetonMolBio and Chuangye Yan @Tsinghua_Uni use it to reveal fascinating insights into in-cell cholesterol sensing with a digitonin-bound SCAP/Insig-2 complex.
Nieng Yan retweeted
This is the source of funding that FBI is charging my MIT colleague, Gang Chen, of going to length to hide. I found the place where he hid it—a place called internet.
The Molecular Biology Dept @PrincetonMolBio at Princeton University invites applications for a tenure-track faculty position at the Assistant Professor level for cryo-EM/ET. Applications are accepted online at princeton.edu/acad-positions…. All materials must be received by 11/1/20.
Nieng Yan retweeted
Our new work is finally out!🍻 Extended from previous results, graphene grids are applied to establish a convenient workflow for cryo-EM analysis of liposome-embedded MPs. So many thanks to Nieng and Xia! More to be explored when everything back to normal
pnas.org/content/early/2020/…
Truly honored! Thank you @BlavatnikAwards
Congratulations to the 2020 Finalists of the Blavatnik National Awards!
bit.nyas.org/30P3Web @ClarkSchool @UofMaryland @Hafezi_Mohammad @MIT @MITnews @JQInews @MaterialsUM #umd #umdcs @yale @yalefaculty @brangwynnelab @NiengYan #WomenInScience #WomeninSTEM #Blavatnik2020
So proud of my amazing team molbio.princeton.edu/news/ma…
The first Nav that I've ever worked on. A 12-year journey. Thanks to my postdoc, Dr. Shuai Gao, a chemist who found out the trick to tame NaChBac -- high pH! Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na+ channels in nanodisc biorxiv.org/content/10.1101/…
EM/ET 🤗💪💪
It all comes down to this!
#JBCMethodsMadness CHAMPIONSHIP VOTE: #TeamMassSpec vs. #TeamCryo – Which method should be crowned champion?
49%Mass Spectrometry
51%Cryo–EM/ET
4,076 votes • Final results Nieng Yan retweeted
Preprint of our cryo-ET work showing the Luminal Ring, a novel structure of the gigantic NPC complex.
Molecular architecture of the luminal ring of the Xenopus laevis nuclear pore complex biorxiv.org/cgi/content/shor… #bioRxiv
Cryo-EM (not ET) structure of NPC!!! Congratulations to Yigong and his remarkable team! disq.us/t/3nanmts
Seeing is believing! A real "ball-and-chain", quite different from the Nav channels. Congrats to Crina and her team! Ball-and-chain inactivation in a calcium-gated potassium channel disq.us/t/3n0eaid