Patricia Yuste retweeted
Structural & functional analysis revealed that the extracellular #chaperone #clusterin functions through two hydrophobic tails in preventing protein aggregation.
❕Publication: nature.com/articles/s41594-0…
❕Press Release: biochem.mpg.de/structure-of-…
#Alzheimers @NatureSMB @PYusteCheca
Patricia Yuste retweeted
New online! Structural analyses define the molecular basis of clusterin chaperone function bit.ly/47kDZ8k
Patricia Yuste retweeted
Regulated proteolysis induces aberrant phase transition of biomolecular condensates into aggregates; a protective role for the chaperone Clusterin: sciencedirect.com/science/ar…
Very excited to share the structure and functional characterization of Clusterin, a key extracellular chaperone and apolipoprotein (ApoJ) linked to cancer, cardiovascular pathology and neurodegeneration. biorxiv.org/content/10.1101/…
Patricia Yuste retweeted
Scientists from the Hartl Department show that the protein #Urm1 protects other proteins in cellular stress situations by promoting phase separation.
❕Publication: cell.com/cell/fulltext/S0092…
❕Press release: biochem.mpg.de/urm1-protects…
@CellPressNews
Patricia Yuste retweeted
Escucha a José Manuel Moreno (catedrático y miembro @IPCC_CH ) : “Quitar carriles-bici es una ideología de fanáticos y lunáticos que van a causar muertes”. Así, sin pelos en la lengua hoy en el Congreso de los Diputados
Patricia Yuste retweeted
I am delighted to announce that my PhD work has finally been published, in which we uncovered a novel role for GCN1 in mitigating translational readthrough.
#collision #readthrough #GCN1 @MPI_Biochem
sciencedirect.com/science/ar…
A thread. 🧵 1/18
Patricia Yuste retweeted
A team led by Ulrich Hartl found out that the protein GCN1 helps to secure the "accident site" after two #ribosomes collided and calls other complexes to degrade the defective #mRNA @CellCellPress
❕ press release biochem.mpg.de/can-we-promot…
❕ full article cell.com/cell/fulltext/S0092…
Patricia Yuste retweeted
Dr. Paul Janssen, the founder of Janssen pharmaceutica (now J&J), was one of the most prolific drug discovery scientists ever. Between 1953-1991 Janssen and his team discovered >70 new medicines.
I enjoyed this paper about his R&D philosophy: onlinelibrary.wiley.com/doi/…
Patricia Yuste retweeted
At ADPD 2023, scientists showed that biosensor cell lines that detect tau seeds do make tau fibrils. A chaperone tears them apart. Does this happen in the #alzheimersdisease brain? @adpdnet @UTSWNews @MPI_Biochem @MRC_LMB ow.ly/4yyr50NEGeq
Patricia Yuste retweeted
Joint Statement from German Postdoctoral Networks on the Eckpunktepapier from the BMBF
postdocnet.mpg.de/127851/Sta…
with
@MunichPostdoc
@LeibnizPostDocs
@Health_talents
@FMP_MDC_PDA
@PAW_Germany
@SociedadCerfa
@RedeApoena
@awi_postdocteam
and more.
#WissZeitVG
#ichbinhanna
Patricia Yuste retweeted
Join us for a PhD in the Protein Biogenesis lab @TheCrick ! We have a very exciting project aimed at understanding how human cells orchestrate the folding of different proteins at the ribosome. crick.ac.uk/careers-study/va…
Patricia Yuste retweeted
The final version of our manuscript is now online: nature.com/articles/s41467-0…
Thanks so much to @Itikasaha and all our friends and collaborators that were part of this journey
@ruferbus @IrinaDudanova @DavidWSanders2 @PYusteCheca
Check out our latest review about the diverse functions of the extracellular chaperone Clusterin in the pathogenesis of neurodegenerative diseases
doi.org/10.1002/bies.2021002…
Patricia Yuste retweeted
Hoy la precariedad de los postdocs tiene un altavoz en @elpais_espana gracias a @ElisaSilio . @CienciaGob , @UniversidadGob , es necesario actuar YA. @FJIprecarios @CientificoenEsp @postdoc_es elpais.com/educacion/univers…
