@PetersonLab

Official twitter feed of the Peterson Lab at the University of Massachusetts Medical School

 Worcester, MA
umassmed.edu/petersonlab/
Joined May 2015
  • Tweets276
  • Following329
  • Followers662
56Media
🚨 TENURE-TRACK Faculty Opportunity The Genome Integrity Program @UMassChan umassmed.edu/genomeintegrity… Join us exploring DNA replication/repair with Core services supporting your cutting-edge research. 🔗 Learn more: academicjobsonline.org/ajo/j… #Genomics #FacultyJobs #Research #Science

Genome Integrity

Genome Integrity, UMass Chan Medical School. Genome integrity, DNA, RNA, DNA damage, DNA replication, replication stress, replication gaps (Gaps), single stranded DNA (ssDNA), Double stranded DNA...

umassmed.edu
1
27
2
56
10,391
BioRxiv: Revised Mechanism of Hydroxyurea Induced Cell Cycle Arrest and an Improved Alternative dlvr.it/T3cq4C
1
4
11
2,068
Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch dlvr.it/T375vD
4
30
5,445
We observed how Sirt6 interacts with the nucleosome, by engaging with the DNA, acidic-patch, H3 and H2A C-terminal tail. /3
1
5
805
The dynamic behavior of Sirt6 provides clues for how it can deacetylate both H3K9 and H3K56 /4
2
4
1,192
I’m excited to share a new manuscript on Sirtuin6-nucleosome structure, a result of a great collaboration between @PetersonLab, Song Tan’s, and @valendraica labs. /1 biorxiv.org/content/10.1101/…
10
24
1
93
16,240
Very very sad news.
J. Tushir-Singh, Ph.D.
@TushirSingh_Lab11 Feb 2023
Just sharing another sad news with the scientific community. The Pioneering molecular biologist Dr. Michael Green, M.D. Ph.D., HHMI and NAS member from Umass Med. School, passed away today with a stroke. Dr. Green revolutionized our understanding of transcription factors. RIP
1
5
15
14,831
Peterson Lab retweeted
Joe Loparo@JoeLoparo18 Nov 2022
This feels like posting into the abyss but for any of you that are still following along... our manuscript with @PetersonLab on the mechanism of SWR1C-mediated H2A.Z deposition is now out in Nature Comms. rdcu.be/cZUup
1
18
BREAKING: Vice President Kamala Harris casts the tie-breaking vote as the Senate passes a historic, landmark bill to combat climate change, tax the rich, drastically lower the costs of prescription drugs for struggling seniors. RT IF YOU’RE GLAD THAT KAMALA REPLACED MIKE PENCE!
2,491
16,536
557
61,477
Welcome to our new Molecular Medicine Faculty member: Dr. Jessica Spinelli @JessicaSpinel16 @UMassChanGSBS @RogerJDavis1
3
5
2
85
Peterson Lab retweeted
Liam Holt@LiamHoltLab2 Mar 2022
Finally published in eLife! “SWI/SNF senses carbon starvation with a pH-sensitive low complexity sequence”. We elucidated a new molecular mechanism by which cells detect and respond to pH-changes. Tweetorial (1/5): elifesciences.org/articles/7… With @alexholehouse @PETERSONlab
6
30
4
157
Peterson Lab retweeted
Liam Holt@LiamHoltLab2 Mar 2022
We found that cells that successfully reprogram transcription in response to carbon starvation actually have to acidify and then re-neutralize – transient acidification is key – and we found a molecular sensor on the SWI/SNF chromatin remodeler, remember polyglutamines?… 2/5
1
1
9
SWR1C catalyzes H2A.Z deposition by coupling ATPase activity to the nucleosome acidic patch dlvr.it/SF3KWW
5
19
The Krietenstein lab (soon to start at CPR/Copenhagen) is looking for post doc candidate to study mechanisms of 3D genome organization. Come and join us! Apply here: jobportal.ku.dk/videnskabeli… Please RT.
2
48
3
74
Congratulations to Craig Peterson PhD - recipient of the 2021 GSBS Dean's Award!! tinyurl.com/f2wf8br8 @PetersonLab @RogerJDavis1 @GSBS_UMassMed @UMassMedical
1
6
2
61
Peterson Lab retweeted
Sara Luzzi@luzzi_s9 Mar 2021
#EESGenomeInstability I am a bit biased 'cause I always enjoy INO80 stories even after finishing my PhD, but @PetersonLab gave a really fantastic talk today on how INO80 helps resolve transcription-replication conflicts! Check their paper here: sciencedirect.com/science/ar…
2
13
Peterson Lab retweeted
Liam Holt@LiamHoltLab5 Mar 2021
Excited to announce our latest @bioRxiv preprint! “SWI/SNF senses carbon starvation with a pH-sensitive low complexity sequence”. We elucidated a new molecular mechanism by which cells detect and respond to pH-changes. Tweetorial follows (1/5): tinyurl.com/86s4p9z7
5
22
5
133
Peterson Lab retweeted
Liam Holt@LiamHoltLab5 Mar 2021
2/5 We found that cells that successfully reprogram transcription in response to carbon starvation actually have to acidify and then re-neutralize – transient acidification is key – and we found a molecular sensor on the SWI/SNF chromatin remodeler, remember polyglutamines?…
2
1
8
Peterson Lab retweeted
Liam Holt@LiamHoltLab5 Mar 2021
3/5 Glutamine-rich low-complexity sequences (QLCs) are everywhere! And they are enriched in histidines! SWI/SNF has 5 such QLCs, but the biggest is on SNF5. Genome-wide reprogramming required pH-oscillation, the SNF5 QLC and its histidines. (@BrittinghamGreg analyzed.)
1
1
9
Save the date: @ASBMB Meeting on Transcriptional Regulation: Chromatin and RNA Polymerase II takes place Oct 1-5, 2020 in Snowbird, Utah. asbmb.org/meetings-events/tr…
1
23
2
46
Load more