Postdoc in the @Doulatov_lab studying evolution of complex karyotype leukemia using single cell technologies.
Joined August 2022
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J. Philip Creamer retweeted
What a beautiful evening at #LightTheNight 2026! ✨ Thank you @BloodCancerUnited for the recognition, and thanks to everyone who donated and supported my fundraiser, especially my PI and lab members @Doulatov_lab! Let’s keep pushing toward a future without blood cancer! 🧑🔬🧪
J. Philip Creamer retweeted
What a fantastic talk n a unique application from @phd_cream @doulatov_lab last week! Our @10xgenomics users continue to inspire us n educate us every single day! #AML #copynumber #karyotype #CNV #CIN.
J. Philip Creamer retweeted
With record participation from postdoc and ARS union members, an overwhelming 90% voted YES to authorize our bargaining committee to call a strike if necessary to win a fair third contract! ✊🔥
J. Philip Creamer retweeted
THE MYELOID WORKSHOP IS ON! inside of ASH, , we responded to your feedback and will start 1 hour ealier and pack more talks in! for speaking slots contact section leaders or organizers, ASH page will be up soon @SteidlUli
J. Philip Creamer retweeted
Thank you to Columbia Herbert Irving Cancer Center @columbiacancer for highlighting our recent work on AML-CK evolution!! Check it out 👇
New research‼️🩸 from Sergei Doulatov and Philip Creamer introduces the first experimental model of AML-CK, identifying chromosome 5q loss as a key driver of disease progression and a shared genetic signature that could guide new therapies. @ColumbiaMed cancer.columbia.edu/news/new…
J. Philip Creamer retweeted
New research‼️🩸 from Sergei Doulatov and Philip Creamer introduces the first experimental model of AML-CK, identifying chromosome 5q loss as a key driver of disease progression and a shared genetic signature that could guide new therapies. @ColumbiaMed cancer.columbia.edu/news/new…
J. Philip Creamer retweeted
Earlier this week I posted an example of a fake western blot provided by ThermoFisher to demonstrate the validity of a p53 antibody. I considered it an amusing curiosity. In fact ThermoFisher has systematically manipulated antibody validation data. Short Thread... 🧵
J. Philip Creamer retweeted
This work was led by Philip Creamer @PhD_Cream, with @r_Suhita and an amazing group of collaborators @SwisherLab and many others. We are grateful for the support from NIH, #EdwardPEvansFoundation, @BloodCancerUtd. @columbiacancer, @ColumbiaPHY.(5/5)
J. Philip Creamer retweeted
AML-CK respond very poorly to therapy. We modeled venetoclax and show that VEN resistance is driven by outgrowth of erythroid/MEP-like clones that express low BCL2. These MEP-like clones are sensitive to JAK2 inhibitors, nominating VEN + JAK2i as a therapeutic strategy. (4/5)
J. Philip Creamer retweeted
Tracking aneuploid evolution at single cell level, we find complex karyotypes converge on an i-CK program with expression of genome stability and anti-apoptotic genes. i-CK signature is UP in most AML-CK patients. We think this reflects adaptation of HSPC to aneuploidy. (3/5)
J. Philip Creamer retweeted
Aneuploidy is a hallmark of MDS and AML with complex karyotype/CK and TP53 loss. We develop an iPSC-based model in which preleukemic TP53 mutant HSPCs evolve to complex aneuploid states. We first show that TP53 and 5q loss cooperate to drive CK evolution. (2/5)
J. Philip Creamer retweeted
Excited to share our latest work in Blood @BloodPortfolio! We uncover how complex chromosomal changes or aneuploidy arises and evolves in hematopoietic stem cells, driven by 5q loss, leading to aggressive blood cancers. Led by JP Creamer @PhD_Cream. More👇ashpublications.org/blood/ar…
J. Philip Creamer retweeted
I don’t tweet much so I’ll keep this simple
We are looking to recruit 1-2 new postdoctoral fellows, to study human hematopoietic development, from both basic and translational perspectives, using iPSCs.
Please reach out via email for more details if interested!
Tired of paying $300 for centrifuge adapters? Just 3D print one!
printables.com/model/1389317…
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J. Philip Creamer retweeted
#hemsrc Thank you to all of our panelists for the career development session at the FASEB hematologic malignancies meeting! Such great advice!
Powered by gummy bears….
J. Philip Creamer retweeted
Looking forward to welcoming everyone to the FASEB Heme Malignancies meeting on Sunday! As you are packing, we wanted to let you know that there is a gym, basketball court, and pool on site! Also, options for hiking at the brewery social event! 🏊♀️🏀🏋️♀️
Safe travels!
#HEMSRC
J. Philip Creamer retweeted
NCI Interim Funding Policy:
“With these considerations, we expect to fund through the 4th percentile for those established investigator applications.”
“It is expected that funds will be available to reach the 10th percentile for those Early Stage Investigator applications.” 😢